Cell Death News and Research

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Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Ciprofloxacin may disrupt normal functions of connective tissue

The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment

26 Jul 2018

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication.

25 Jul 2018

Scientists find abnormal gene copying in fruit fly models of tauopathies

It sounds like science fiction: Nefarious genes clone themselves and settle their rogue copies in distant outposts of the galaxy (namely, our DNA), causing disease.

24 Jul 2018

Restoring mitochondrial function to reverse aging-related skin wrinkles, hair loss in mice

Wrinkled skin and hair loss are hallmarks of aging. What if they could be reversed?

20 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Researchers develop new, less destructive method for whitening teeth

In the age of Instagram and Snapchat, everyone wants to have perfect pearly whites. To get a brighter smile, consumers can opt for over the counter teeth-whitening treatments or a trip to the dentist to have their teeth bleached professionally.

18 Jul 2018

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Numerous studies to date have shown that olfactory receptors are relevant not only for smell perception, but that they also play a significant physiological and pathophysiological role in all organs.

16 Jul 2018

Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

A KAIST research team developed near-infrared fluorophores-based photodynamic therapy that reduced the downside of existing PDTs.

16 Jul 2018

Traumatic brain injury biomarker could help predict patient prognosis

A preclinical study has shown that levels of lysophosphatidic acid (LPA) are significantly increased following traumatic brain injury (TBI).

16 Jul 2018

Molecules formed when the body metabolizes omega-3 fatty acids may inhibit cancer

A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer's growth and spread, University of Illinois researchers report in a new study in mice.

16 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

Study reveals how M. tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens.

10 Jul 2018

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Researchers from the Department of Cell Biology, Physiology and Immunology and the Institute for Biotechnology and Biomedicine of the Universitat Autònoma de Barcelona have unmasked the functioning of a protein involved in DNA repair, ATR, in the meiotic recombination process which takes place during the development of spermatocytes - sperm precursor cells- and how inhibiting this protein causes anomalies which block spermatogenesis.

9 Jul 2018

Established lung fibrosis can be reversed using diabetes drug treatment

Researchers at the University of Alabama at Birmingham have shown - for the first time - that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

2 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018

Researchers scale up fluorescence imaging technique to analyze larger areas

Researchers have scaled up a powerful fluorescence imaging technique used to study biological processes on the cellular level. Previously limited to samples just millimeters in area, the expanded approach can analyze samples with areas up to 4 square centimeters.

27 Jun 2018

Cell Death News and Research

Scientists use new drug discovery system to target Huntington’s Disease

Scientists use new drug discovery system to target Huntington’s Disease

Ciprofloxacin may disrupt normal functions of connective tissue

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

Scientists find abnormal gene copying in fruit fly models of tauopathies

Restoring mitochondrial function to reverse aging-related skin wrinkles, hair loss in mice

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

Researchers develop new, less destructive method for whitening teeth

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

Traumatic brain injury biomarker could help predict patient prognosis

Molecules formed when the body metabolizes omega-3 fatty acids may inhibit cancer

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

Study reveals how M. tuberculosis escapes death in macrophages

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Researchers unmask functioning of protein involved in DNA repair during spermatogenesis

Established lung fibrosis can be reversed using diabetes drug treatment

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

Researchers scale up fluorescence imaging technique to analyze larger areas

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

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Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics