Central Nervous System News and Research

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Study shows parvalbumin-interneurons in the amygdala influence fear memory encoding

Fear memory encoding, the process responsible for persistent reactions to trauma-associated cues, is influenced by a sparse but potent population of inhibitory cells called parvalbumin-interneurons (PV-INs) in the amygdala, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online July 14 in the journal Neuron.

14 Jul 2016

Researchers identify new drug target for treating children with CNS-PNET

Primitive neuroectodermal tumors (PNETs) are the largest group of malignant brain tumors in children. They can arise from the brain's cerebellum or, more rarely, from tissue located throughout the central nervous system (CNS).

14 Jul 2016

Combination approach could be more effective to treat fibromyalgia pain

Queen's University researcher Ian Gilron has uncovered a more effective way of treating fibromyalgia, a medical condition characterized by chronic widespread pain typically accompanied by fatigue, as well as sleep, mood and memory problems.

14 Jul 2016

Scientists create new eye technology for detecting Alzheimer's before onset of symptoms

Scientists may have overcome a major roadblock in the development of Alzheimer's therapies by creating a new technology to observe - in the back of the eye - progression of the disease before the onset of symptoms.

11 Jul 2016

Scientists succeed in restoring multiple key aspects of vision in mice

Experiments conducted under the leadership of a Stanford University School of Medicine investigator have succeeded, for the first time, in restoring multiple key aspects of vision in mammals.

11 Jul 2016

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

A deadly bacteria that can be picked up by a simple sniff can travel to the brain and spinal cord in just 24 hours, a new Griffith University and Bond University study has found.

11 Jul 2016

New research shows how cholesterol medicine has beneficial effect on immune defence system

The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defence system with regard to diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

7 Jul 2016

Sub-sensory vibratory noise leads to greater postural control, improved mobility in older adults

Researchers from the Harvard affiliated Hebrew SeniorLife Institute for Aging Research, have published a recent article in the Journal of NeuroEngineering and Rehabilitation which gives evidence that sub-sensory vibrations delivered to the foot sole of older adults significantly augmented the physiologic complexity of postural control and led to improvement in a given mobility assessment.

7 Jul 2016

Daclizumab drug offers new treatment option for people living with relapsing forms of MS in the UK

A new, first-in-class treatment which is believed to use a double-action approach to fight MS by rebalancing the immune system, has today been authorised in the UK for people living with relapsing forms (the most common type) of the disease.

7 Jul 2016

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Minoryx Therapeutics, a drug development company specialized in the discovery and development of new drugs for orphan diseases, today announces the initiation of its first-in-man Phase 1 clinical trial for its lead compound MIN-102.

7 Jul 2016

Study finds no substantial link between gadolinium exposure and parkinsonism

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

6 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

Researchers discover surprising mismatch on either side of dopaminergic synapses

Neurons are cells that transmit nerve impulses. Dopamine neurons are the main source of the chemical dopamine in the central nervous system and are few in number compared to other types of neurons in the brain.

1 Jul 2016

Researchers examine effect of GluD2 receptor on parallel fibre regeneration

Nerves in the central nervous system of adult mammals do not usually regenerate when injured. The granule cell, a nerve cell located in the cerebellum, is different.

30 Jun 2016

The future of simulated teaching methods

In healthcare, we have physicians, nurses and paramedics who know the textbook by heart and know exactly what they need to do, but have never experienced the procedure first-hand, or they have no experience responding to adverse events that may occur.

24 Jun 2016

Two simple measures can help decrease incidence of POCD in older patients

Post-operative cognitive dysfunction (POCD), a condition mostly observed in older patients following surgery under general anesthesia, is characterized by impaired memory and concentration. The impairment may be temporary or permanent and incapacitating.

23 Jun 2016

New optogenetic manipulation technique could possibly reduce migraine headaches

Despite decades of research, migraines are often not well controlled with medication. For those prone to this type of debilitating headache, it sometimes seems nothing can stop the pain and the sensitivity to light. But what if light itself was key to their relief?

23 Jun 2016

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity.

22 Jun 2016

NYU Tandon students use smartphones to improve stroke rehabilitation

A team of students from the NYU Tandon School of Engineering is using smartphones to improve the arduous and repetitive process patients must typically undergo to relearn the basic skills they lose after suffering a stroke.

21 Jun 2016

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

In a small study looking at pain assessments in adults with sickle cell disease, researchers at Johns Hopkins says overall, those treated long-term with opioids often fared worse in measures of pain, fatigue and curtailed daily activities than those not on long-term opioids.

21 Jun 2016

Central Nervous System News and Research

Study shows parvalbumin-interneurons in the amygdala influence fear memory encoding

Researchers identify new drug target for treating children with CNS-PNET

Combination approach could be more effective to treat fibromyalgia pain

Scientists create new eye technology for detecting Alzheimer's before onset of symptoms

Scientists succeed in restoring multiple key aspects of vision in mice

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

New research shows how cholesterol medicine has beneficial effect on immune defence system

Sub-sensory vibratory noise leads to greater postural control, improved mobility in older adults

Daclizumab drug offers new treatment option for people living with relapsing forms of MS in the UK

Minoryx Therapeutics initiates phase 1 clinical trial of MIN-102

Study finds no substantial link between gadolinium exposure and parkinsonism

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Researchers discover surprising mismatch on either side of dopaminergic synapses

Researchers examine effect of GluD2 receptor on parallel fibre regeneration

The future of simulated teaching methods

Two simple measures can help decrease incidence of POCD in older patients

New optogenetic manipulation technique could possibly reduce migraine headaches

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

NYU Tandon students use smartphones to improve stroke rehabilitation

Long-term opioid therapy may not be effective to manage pain in sickle cell disease patients

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