Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

A new Brown University study projects that increasing the number of Rhode Islanders treated every year for hepatitis C virus infection (HCV) to about 2,000 by 2020 would reduce cases by 90 percent and prevent more than 70 percent of expected liver-related deaths in the state by 2030.

5 Aug 2016

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults.

5 Aug 2016

New lung scanning platform holds potential to improve treatment for people with lung disease

New lung scanning technology developed at Monash University has the potential to transform treatment for millions of people with lung disease in Australia and around the world.

5 Aug 2016

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Insilico Medicine, Inc in collaboration with scientists from Atlas Regeneration, Inc, Vision Genomics, Inc and Howard University published two research papers on fibrosis in the lung and liver and fibrotic signatures in glaucoma.

30 Jul 2016

Researchers identify new mechanisms capable of suppressing propagation of HCV

Researchers at Osaka University, Japan uncovered the mechanisms that suppress the propagation of the hepatitis C virus (HCV) with the potential of improving pathological liver conditions.

27 Jul 2016

Groundbreaking research opens door for prevention of cardiac fibrosis

Groundbreaking research from the University of Alberta and McGill University has opened the door towards the future prevention of cardiac fibrosis—a condition leading to heart failure for which there is currently no treatment.

27 Jul 2016

New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

Research into Africa's first 'screen-and-treat' programme for hepatitis B suggests the initiative may reduce deadly complications of the virus.

27 Jul 2016

Testing lung health online: an interview with Professor Stephen Holgate

In our latest report – The Battle for Breath – the impact of lung disease in the UK, figures suggest that 1 in 5 (around 12.7 million) have been diagnosed with a lung condition in the UK. If you’re over the age of 70, this rises to 1 in 3.

From Asthma + Lung UK 27 Jul 2016

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme.

26 Jul 2016

Adding DNA sequencing to newborn screenings may increase early diagnosis of cystic fibrosis

A study by researchers at Children's Hospital Los Angeles, Brigham and Women's Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive additional screening in order to better predict the risk of developing CF later in life.

26 Jul 2016

Scientists discover group of genes that can help predict damage in transplanted kidney

A multicenter team of researchers led by Barbara Murphy, MD, of the Icahn School of Medicine at Mount Sinai has identified a panel of genes which can help predict whether a transplanted kidney will later develop fibrosis, an injury which can cause the organ to fail. Their results were published in the July 21 edition of Lancet.

22 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

Researchers discover how Zika virus travels from pregnant mother to fetus

Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UC San Francisco and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus. They also identify a drug that may be able to block it.

19 Jul 2016

Fibrosis News and Research

Further Reading

Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

New lung scanning platform holds potential to improve treatment for people with lung disease

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Researchers identify new mechanisms capable of suppressing propagation of HCV

Groundbreaking research opens door for prevention of cardiac fibrosis

New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

Testing lung health online: an interview with Professor Stephen Holgate

Male hormones can reverse biological drivers of aging, study shows

Adding DNA sequencing to newborn screenings may increase early diagnosis of cystic fibrosis

Scientists discover group of genes that can help predict damage in transplanted kidney

BET inhibitor treatment decreases lung inflammation in mice

Researchers discover how Zika virus travels from pregnant mother to fetus

New report reveals prescription medication costs may increase up to 13% in 2016

Scientists uncover structure of cold virus linked to severe asthma, respiratory infections in children

Sex-related difference could have impact on treatment of metabolic diseases

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Tiny viruses speed-up evolution of bacteria causing infections in cystic fibrosis patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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