Polymerase News and Research

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SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

The study found that the delta and epsilon variants exhibited significantly higher infectivity than alpha, with delta containing approximately six times as much infectious virus for the same amount of RNA.

22 Sep 2021

Three US COVID-19 vaccines provide substantial protection against hospitalization

A new study reports that a head-to-head comparison of the efficacy of the three vaccines used in the USA indicates substantial protection against hospitalization with COVID-19 following vaccination with any of these vaccines.

21 Sep 2021

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Guinea recently experienced its second outbreak of the Ebola virus disease within the last decade.

19 Sep 2021

Combining antibody markers to improve serosurveillance for SARS-CoV-2

The current study found that combining N antibodies with nucleocapsid-specific IgG facilitates a better classification of SARS-CoV-2 infection.

19 Sep 2021

A variant analysis approach for SARS-CoV-2 in wastewater samples

A recent study proposes a simple and specific method for the enhanced detection of the SARS-CoV-2 VOCs in wastewater samples.

19 Sep 2021

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

In a recent study, Swiss researchers use improved techniques to understand the biological significance behind the Delta variant.

19 Sep 2021

R37 MERIT Award supports innovative ovarian cancer research

One of the most impactful advancements during the past decade in treating ovarian cancer is the use of PARP inhibitors (short for poly adenosine diphosphate-ribose polymerase). PARP inhibitors are a type of cancer drug that blocks the PARP enzyme from helping to repair DNA damage in cancer cells.

18 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Beckman Coulter Life Sciences debuts the future of simplified PCR cleanup and plasmid prep with the EMnetik system

Creating the industry’s first powerful workflow innovation in more than 30 years for plasmid prep and polymerase chain reaction cleanup, Beckman Coulter Life Sciences launches the EMnetik System to semi-automate workflows while drastically reducing the amount of time required to achieve a PCR cleanup.

From Beckman Coulter Life Sciences - Flow Cytometry 16 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

A new study focused on in vitro antiviral activity in various cell models and in vivo therapeutic efficacy of oral GS-621763 in a mouse model of SARS-CoV-2 pathogenesis.

15 Sep 2021

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

A recent study aimed to use their own classification of different SARS-CoV-2 lineages that would help monitor their genetic features and geographical origins.

14 Sep 2021

Prior symptomatic COVID-19 enhances mRNA vaccine response

A new paper describes the antibody responses in people who have already been infected with SARS-CoV-2 and are vaccinated as compared to the naïve.

14 Sep 2021

SARS-CoV-2 infections surged in England this summer, despite high vaccine uptake

Researchers in the UK have warned that England experienced a rapid exponential increase this summer in the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – despite high rates of vaccination uptake.

14 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Polymerase News and Research

SARS-CoV-2 delta variant has higher viral RNA levels and increased infectivity, suggests study

Three US COVID-19 vaccines provide substantial protection against hospitalization

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Combining antibody markers to improve serosurveillance for SARS-CoV-2

A variant analysis approach for SARS-CoV-2 in wastewater samples

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

R37 MERIT Award supports innovative ovarian cancer research

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Beckman Coulter Life Sciences debuts the future of simplified PCR cleanup and plasmid prep with the EMnetik system

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

Prior symptomatic COVID-19 enhances mRNA vaccine response

SARS-CoV-2 infections surged in England this summer, despite high vaccine uptake

GIST researchers unravel coordination mechanism of base excision repair

Dynamics of healthcare-associated SARS-CoV-2 infections revealed with whole genome sequencing

Guidelines: Summer camp returns to normal during COVID-19

New SARS-CoV-2 mechanism of host gene suppression

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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