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Gene mutation discovery leads to novel treatment for patient with severe lymphatic condition

Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge to develop a novel treatment that dramatically improved the problem.

2 Jul 2019

New target identified for treatment of idiopathic pulmonary fibrosis

An article published in Experimental Biology and Medicine (Volume 244, Issue 9, June 2019) (https://journals.sagepub.com/doi/pdf/10.1177/1535370219843827) identifies a new target for the treatment of idiopathic pulmonary fibrosis.

29 Jun 2019

Space station mold may be tougher to kill than previously expected

A new study shows that mold spores are present inside the station and may also survive on the outside walls of the International Space Station (ISS)

28 Jun 2019

Study shows how gastric stem cells fight colonizing bacteria

Stem cells are not only key players in tissue regeneration, they are also capable of taking direct action against bacteria.

25 Jun 2019

Researchers identify missing link between amyloid plaques and tau tangles in Alzheimer's

Years before symptoms of Alzheimer's disease appear, two kinds of damaging proteins silently collect in the brain: amyloid beta and tau. Clumps of amyloid accumulate first, but tau is particularly noxious.

25 Jun 2019

Switch that decides fate of cells from neural stem cells discovered

Neurons and astrocytes are prominent cell types in the cerebral cortex. Neurons are the primary information processing cells in the brain, whereas astrocytes support and modulate their functions.

24 Jun 2019

Introduction of very small RNA molecule promotes heart cell regeneration, study shows

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function.

23 Jun 2019

Most preferred drug for HIV may not be as safe as suggested

A study lead by researchers at the Institute of HIV Research, Medical Faculty of UDE and University Hospital Essen, stumbled over a potential toxicity of integrase inhibitors.

21 Jun 2019

High levels of acid in processed foods could affect fetus' developing brain

With the number of children diagnosed with autism on the rise, the need to find what causes the disorder becomes more urgent every day. UCF researchers are now a step closer to showing the link between the food pregnant women consume and the effects on a fetus' developing brain.

20 Jun 2019

Dangerous brain parasite invades host cell, maintains steady nutrient supply

A team of researchers has found that a dangerous type of parasite that affects the brain, maintains a stable supply of essential nutrients as it replicates in the host cell. In an unexpected turn of events, the body itself delivers food to the harmful predator.

20 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

Researchers find possible counterpunch to drug resistance of melanoma

Researchers at Oregon State University and Oregon Health & Science University have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer.

19 Jun 2019

Researchers develop DNA nanorobots that target breast cancer cells

According to the Mayo Clinic, about 20% of breast cancers make abnormally high levels of a protein called human epidermal growth factor receptor 2 (HER2).

17 Jun 2019

Urinary DKK3 can improve prediction of AKI

A new renal biomarker was presented at the ERA-EDTA Congress last year: that shows that urinary DKK3 might help to identify patients who are at risk of progressive chronic kidney disease.

17 Jun 2019

Mount Sinai researchers win a contract from DARPA to develop technology that measures threat exposures

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a contract from the Defense Advanced Research Projects Agency, a research agency within the U.S. Department of Defense, to find molecular signatures in blood that identify previous exposures and time of exposure to materials that could be associated with weapons of mass destruction (including infectious agents, chemicals, and radiation).

13 Jun 2019

Polycomb protein EED plays a complex role in brain development

The dentate gyrus (DG) is the input region of the hippocampus and plays an important role in learning and memory.

13 Jun 2019

Heart failure drug could be effective in treating leukemia

Canadian researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. Those efforts have borne fruit, as demonstrated by their work published in the Journal of Experimental and Clinical Cancer Research.

13 Jun 2019

Ultra-fast new technology to detect bacteria

A new detection method which can identify the presence of bacteria within a minute, while distinguishing healthy from non-viable bacteria, could save many lives and a lot of money. Scientists at the University of Warwick reported this technology, based on alterations in electrical signaling in bacteria in response to external electrical stimulation.

13 Jun 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Biomarker correlates with prostate cancer aggressiveness and predicts metastasis to bone

Mortality due to prostate cancer is usually related to its likelihood to metastasize, especially to bone. Prognostic biomarkers are urgently needed to predict disease aggression so that appropriate treatment can be selected.

12 Jun 2019