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Gene therapy shows promise as treatment for diseased lower limbs at risk for amputation

New research suggests that gene therapy is a safe treatment method to explore in patients whose lower limbs are at risk for amputation because of poor circulation caused by blocked blood vessels.

27 Feb 2007

Stimuvax investigational lung cancer vaccine phase III study starts

Merck KGaA today announced that the first patient has been enrolled in its global Phase III clinical study, START (Stimulating Targeted Antigenic Responses To NSCLC), assessing the efficacy and safety of Stimuvax (BLP25 liposome vaccine) as a potential treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC).

26 Feb 2007

New bird flu vaccine not such a sure bet

According to the Food and Drug Administration (FDA) in the U.S., in clinical trials the nation's first bird flu vaccine is not as effective as was initially expected.

26 Feb 2007

Statements on peanut butter Salmonella

Statement from FDA - Product testing by several states has now confirmed that Peter Pan peanut butter and certain Great Value brand peanut butter are the sources of the foodborne illness outbreak of Salmonella Tennessee that began in August 2006. To date 329 individuals have become ill from consuming the contaminated peanut butter, and 51 of those persons were hospitalized.

25 Feb 2007

Gambian President claims to cure HIV/AIDS

Gambian President Yahya Jammeh since January has claimed that he can cure HIV/AIDS with an herbal remedy, prompting concern among some public health workers in Africa who already are "struggling against faith healers dispensing herbal remedies," the AP/Monterey County Herald reports.

25 Feb 2007

FDA confirms peanut butter the source of salmonella outbreak affecting over 300

The Food and Drug Administration (FDA) in the United States has confirmed that an outbreak of salmonella food poisoning was caused by contaminated peanut butter.

25 Feb 2007

microRNA directly regulates a gene implicated in human cancers

MicroRNAs are tiny snippets of RNA that can repress activity of a gene by targeting the gene's messenger RNA (which copies DNA information and starts the process of protein production).

22 Feb 2007

Scientists identify specific enzymes that make meningitis hard to fight

Two enzymes in meningitis bacteria which prevent the body from successfully fighting off the disease, and make the infection extremely virulent, have been identified in new research published today.

22 Feb 2007

Pregnancy hormone prolactin gives hope to MS victims

Canadian scientists believe they may be some way to solving the mystery of why women suffering from multiple sclerosis (MS) go into remission while they are pregnant.

21 Feb 2007

Experimental vector vaccine reduces stillbirths from cytomegalovirus

Researchers funded by the National Institutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV) - a common virus that can also cause mental retardation and hearing loss in newborn children who were infected in early fetal life.

21 Feb 2007

Imaging of disease dynamics during meningococcal sepsis

Each year 170,000 people around the world die of this type of meningitis, according to the World Health Organization, (WHO).

21 Feb 2007

Gardasil reaction report released

The National Vaccine Information Center (NVIC) today released a new analysis of the federal Vaccine Adverse Event Reporting System (VAERS) reports of serious health problems following HPV vaccination (Merck's Gardasil) during the last six months of 2006.

21 Feb 2007

New test identifies suitable lymphoma patients likely to respond to new therapy

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered a genetic signature identifying cases of lymphoma that are uniquely susceptible to a newly developed molecular targeted therapy. As a result, physicians organizing clinical trials of the new therapy will be able to enroll patients who'll be most likely to benefit from it.

20 Feb 2007

Hormone prolactin key to repairing nerve cell damage

The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that a pregnancy-related hormone is responsible for rebuilding the protective coating around nerve cells.

20 Feb 2007

Chemotherapy drug bortezomib packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.

20 Feb 2007

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein.

20 Feb 2007

How T cells attack tumors

Our immune system struggles to eliminate tumors effectively. By unraveling its strategies, we can enhance its effects on tumor cells and so improve the clinical prospects of cancer immunotherapy.

20 Feb 2007

Scientists label cells with magnetic nanoparticles

Investigators at the German Cancer Research Center have developed silica-coated iron oxide nanoparticles that allow for cell tracking in a live animal using magnetic resonance imaging (MRI).

20 Feb 2007

Food scare number 4 this week - chicken breast meat

In yet another food scare in the United States a nationwide recall of 52,650 pounds of Oscar Mayer ready to eat chicken breast strips is suspected to be contaminated.

19 Feb 2007

RNAi shows promise in gene therapy

Three years ago Mark Kay, MD, PhD, published the first results showing that a biological phenomenon called RNA interference could be an effective gene therapy technique. Since then he has used RNAi gene therapy to effectively shut down the viruses that cause hepatitis and HIV in mice.

19 Feb 2007