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Scientists present data on denufosol tetrasodium for CF at ATS 2010 International Conference

Inspire Pharmaceuticals, Inc. announced today that Inspire scientists and collaborators will present data on denufosol tetrasodium, an investigational therapy for cystic fibrosis, during an oral presentation at the American Thoracic Society 2010 International Conference May 14 - 19, 2010 in New Orleans, LA.

20 May 2010

Positive data from Geron's TAT153 small molecule telomerase activator in animal model of IPF

Geron Corporation today announced positive data on its orally available small molecule telomerase activator, TAT153, in an animal model of idiopathic pulmonary fibrosis (IPF). The data show that administration of TAT153 increased telomerase activity in the lung tissue, reduced inflammation, preserved functional lung tissue, slowed disease progression and attenuated loss of pulmonary function.

19 May 2010

Study results may help researchers determine genetic abnormalities that cause lung disease to develop

Patients who encounter serious lung diseases in middle age, despite an absence of family history or other predisposing factors, may still have their genes to blame, according to a new study conducted by researchers at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

19 May 2010

Vaccinations recommended for adults

Yearly vaccinations aren't just for kids any more. You probably heard a lot about a seasonal or H1N1 flu shot last fall, but you should know that a battery of other adult vaccinations might also become part of your health care routine. Pneumonia and shingles vaccines are preventive-care essentials for older adults, and meningitis and tetanus shots are now college rites of passage. Even the vaccines of childhood—measles, mumps and rubella, and whooping cough—are recommended for adults who missed out in their younger years.

19 May 2010

NAC therapy shows promise for patients with mild IPF

A new therapy shows promise for patients with mild idiopathic pulmonary fibrosis. According to researchers in Japan, inhaled N-acetylcysteine monotherapy preserves more lung function in some idiopathic pulmonary fibrosis patients than no therapy.

19 May 2010

High school student studies effects of repeated x-rays in HMV children admitted for pneumonia

You expect to find leading experts in the fields of pulmonary, critical care and sleep medicine presenting their research at the annual ATS International Conference-physicians and professors, basic scientists, fellows and post-docs, certainly. High school students? Not so much.

18 May 2010

Study confirms genetic overlap for susceptibility to COPD and lung cancer

New research shows genes that make smokers more likely to develop chronic obstructive pulmonary disease (COPD), or emphysema, are also closely linked to an increased likelihood of developing lung cancer, according to studies presented today at the American Thoracic Society's annual meeting.

18 May 2010

Apnex HGNS System shows promising results in people suffering from OSA

Apnex Medical announced today that preliminary data from a first-in-man clinical study showed significant improvements in sleep for people suffering from obstructive sleep apnea. The Apnex HGNS™ System, developed by the St. Paul-based company, is a device designed to treat OSA, which is a serious life-threatening illness characterized by fragmented sleep and excessive day-time sleepiness.

18 May 2010

FibroGen's FG-3019 human monoclonal antibody against CTGF reverses progression of lung fibrosis

FibroGen, Inc. today announced that administration of investigational therapy FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), reversed the process of fibrosis in a preclinical model of radiation-induced lung fibrosis, a finding that has implications for treating multiple types of fibrotic disease.

18 May 2010

Treatment with MP-376 reduces P. aeruginosa in CF patients: Research

A new possible treatment to treat P. aeruginosa in cystic fibrosis patients appears to be promising, according to research to be presented at the ATS 2010 International Conference in New Orleans.

17 May 2010

Long-term, regular use of vitamin E in women may help decrease risk of COPD: Study

Long-term, regular use of vitamin E in women 45 years of age and older may help decrease the risk of chronic obstructive pulmonary disease by about 10 percent in both smokers and non-smokers, according to a study conducted by researchers at Cornell University and Brigham and Women's Hospital.

17 May 2010

Study describes association between childhood asthma and risk of developing adult COPD

Children with severe asthma have more than 30 times the risk of developing adult chronic obstructive lung disease as adults compared to children without asthma, according to a prospective longitudinal cohort study from the Royal Children's Hospital in Melbourne.

17 May 2010

Phase 2a study results of Aerosurf for prevention of RDS in premature infants published

Discovery Laboratories, Inc., announces the publication of results from its previously-conducted Phase 2a feasibility study of Aerosurf, the Company's aerosolized KL4 surfactant, for the prevention of respiratory distress syndrome in premature infants, in the May 2010 issue of the Journal of Aerosol Medicine and Pulmonary Drug Delivery in the study titled "An Open Label, Pilot Study of Aerosurf Combined with nCPAP to Prevent RDS in Preterm Neonates".

14 May 2010

Pacific Island region on track to meet TB MDG, drug-resistance remains a threat

Experts at the Fifth Pacific Stop Tuberculosis Meeting in Nadi, Fiji, concluded that the Pacific Islands region is on track to meet the Millennium Development Goal of halving TB prevalence by 2015, All Headline News reports in an article about the meeting, which recently concluded.

13 May 2010

Amira Pharmaceuticals' LPA1 receptor antagonist program data published in British Journal of Pharmacology

Amira Pharmaceuticals, Inc. announced today that preclinical data from its LPA1 receptor antagonist program has been published in the British Journal of Pharmacology.

7 May 2010

New data on Surfaxin LS presented at 2010 PAS Annual Meeting

Discovery Laboratories, Inc., announced that new data regarding Surfaxin LS (its novel, lyophilized KL4 surfactant dosage form) were presented at the 2010 Pediatric Academic Societies Annual Meeting. The two studies presented demonstrate that Surfaxin LS improves lung function and oxygenation while attenuating lung inflammation in the preterm lamb model of respiratory distress syndrome.

5 May 2010

FDA's call for further review of pirfenidone disappointing for Pulmonary Fibrosis patients, says CPF

The Coalition for Pulmonary Fibrosis (CPF), representing tens of thousands of patients, is responding to the news that the FDA chose to ask for further study of Pirfenidone, which will delay potential approval of the first drug in the treatment of Pulmonary Fibrosis (PF), a lethal lung disease that is irreversible, progressive and deadly in an average of three years. On March 9, 2010, an FDA Advisory Committee recommended approval of the drug by the FDA.

5 May 2010

Americans and their babies are gaining more body fat: Study

A new study has found for the first time that as Americans are gaining more body fat, so are their babies. The research, which reviewed data from more than 74,000 births, found that a key measure of body fat composition in newborns increased significantly over a 15-year period, mirroring similar increases among pregnant mothers. The findings were presented Sunday by researchers from Children's Mercy Hospitals and Clinics at the Pediatric Academic Societies annual meeting.

5 May 2010

Johns Hopkins researchers identify a key protein that triggers sarcoidosis

Lung researchers at Johns Hopkins have identified a possible protein trigger responsible for sarcoidosis, a potentially fatal inflammatory disease marked by tiny clumps of inflammatory cells that each year leave deep, grainy scars on the lungs, lymph nodes, skin and almost all major organs in hundreds of thousands of Americans.

4 May 2010

Rush Center for Urban Health Equity to focus on disparities in heart and lung disease

Rush University Medical Center has been awarded a $10 million grant from the National Institutes of Health to establish the Rush Center for Urban Health Equity. The aim of the Center is to find ways to promote changes to eliminate the disparities in heart and lung disease affecting inner city residents, in particular those who are low-income persons of color.

4 May 2010

Lung Disease News and Research

Scientists present data on denufosol tetrasodium for CF at ATS 2010 International Conference

Positive data from Geron's TAT153 small molecule telomerase activator in animal model of IPF

Study results may help researchers determine genetic abnormalities that cause lung disease to develop

Vaccinations recommended for adults

NAC therapy shows promise for patients with mild IPF

High school student studies effects of repeated x-rays in HMV children admitted for pneumonia

Study confirms genetic overlap for susceptibility to COPD and lung cancer

Apnex HGNS System shows promising results in people suffering from OSA

FibroGen's FG-3019 human monoclonal antibody against CTGF reverses progression of lung fibrosis

Treatment with MP-376 reduces P. aeruginosa in CF patients: Research

Long-term, regular use of vitamin E in women may help decrease risk of COPD: Study

Study describes association between childhood asthma and risk of developing adult COPD

Phase 2a study results of Aerosurf for prevention of RDS in premature infants published

Pacific Island region on track to meet TB MDG, drug-resistance remains a threat

Amira Pharmaceuticals' LPA1 receptor antagonist program data published in British Journal of Pharmacology

New data on Surfaxin LS presented at 2010 PAS Annual Meeting

FDA's call for further review of pirfenidone disappointing for Pulmonary Fibrosis patients, says CPF

Americans and their babies are gaining more body fat: Study

Johns Hopkins researchers identify a key protein that triggers sarcoidosis

Rush Center for Urban Health Equity to focus on disparities in heart and lung disease

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