Opioids News and Research

RSS

An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects and the side effects of opioids.

Study may help personalize pain medication management for sickle cell disease patients

A study that may help personalize pain medication management for sickle cell disease patients is underway at Georgia Health Sciences University.

9 Dec 2011

Medical websites provide harmful information about postherpetic neuralgia treatments

Health information is plentiful on the Internet and many Web surfers consider medical advice they find online to be a cheaper alternative to visiting a doctor, according to some studies. However, the risk of obtaining useless or even harmful medical information from some websites is high for patients with postherpetic neuralgia, a common complication of shingles, according to new research reported in The Journal of Pain, published by the American Pain Society.

1 Dec 2011

Dramatic nationwide rise in opioid use for chronic abdominal pain

Across U.S. outpatient clinics between 1997 and 2008, opioid prescriptions for chronic abdominal pain more than doubled, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association.

30 Nov 2011

Combination of other opioids with methadone therapy can lead to overdose or fatal consequences

A new study has shown harmful prescription patterns of powerful painkillers among a substantial number of Ontario patients who received methadone therapy to treat their opioid addiction.

29 Nov 2011

Naltrexone for problem gamblers

According to new practice guidelines Australian doctors treating gambling addicts now can consider prescribing an anti-heroin drug, naltrexone, to help problem gamblers control their impulses. Australia has one of the world’s highest rates of problem gamblers, with about 2.1 per cent of Australians experiencing some form of gambling problem.

22 Nov 2011

Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines, today announces that the multiple ascending dose Phase I study of the novel, first in class calcium channel blocker CNV2197944, for the treatment of chronic pain has been initiated.

21 Nov 2011

Viewpoints: Questions of partisanship and timing could complicate Supreme Court's decision on health law

The Supreme Court's decision to review the constitutionality of health care reform means it will be issuing a ruling in the middle of the 2012 presidential campaign. This can be a highly politicized court, and, for the public good and its own credibility, it must resist that impulse.

16 Nov 2011

Researchers explore how design of chronic and acute pain trials might be improved

For chronic pain sufferers, a day can feel like a year and a year can feel like an eternity. With very few truly new therapies approved by the U.S. Food and Drug Administration for this condition since 2005, the outlook is far from bright.

15 Nov 2011

Opioid-dependent patients have worse outcomes before knee replacement surgery

Patients who are dependent on opioids (narcotic pain relievers) for pain management before knee replacement surgery have much more difficulty recovering, a study recently published in the Journal of Bone and Joint Surgery (JBJS) has found.

13 Nov 2011

Positive results from Alkermes VIVITROL addiction study

Alkermes plc today presented positive results from a long-term study of VIVITROL (naltrexone for extended-release injectable suspension) at the 24th Annual U.S. Psychiatric and Mental Health Congress in Las Vegas, NV.

10 Nov 2011

APS supports CDC's call for multifaceted approach to address prescription drug misuse

As reported by the U.S Centers for Disease Control, some 15,000 deaths occurred in the U.S. in 2008 from overdoses of prescription pain medications, and demand for treatment of prescription opioid addiction increased almost six fold between 1999 and 2009.

10 Nov 2011

NIH announces results from first large scale study on treatment of prescription opioid addiction

People addicted to prescription painkillers reduce their opioid abuse when given sustained treatment with the medication buprenorphine plus naloxone (Suboxone), according to research published in yesterday's Archives of General Psychiatry and conducted by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

9 Nov 2011

QRxPharma receives FDA written acceptance for review of MoxDuo IR NDA

QRxPharma Limited announced today it received written acceptance from the United States Food and Drug Administration (FDA) for review of the MoxDuo IR New Drug Application (NDA) filed earlier this year.

9 Nov 2011

Racial/ethnic disparities among adolescents with substance-related disorders

Substance use is widespread among adolescents in the United States, particularly among those of Native American, white, Hispanic and multiple race/ethnicity, and these groups are also disproportionally affected by substance-related disorders, according to a report in the November issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

8 Nov 2011

QRxPharma receives date for US pain drug launch, pending approval

Australian pain-relief drug developer QRxPharma (QRX) has announced today that they have received from the US Food & Drug Adminstration.

8 Nov 2011

Link between heavy methamphetamine use and schizophrenia

In the first worldwide study of its kind, scientists from Toronto's Centre for Addiction and Mental Health (CAMH) found evidence that heavy methamphetamine users might have a higher risk of developing schizophrenia.

8 Nov 2011

First large-scale study to address treatment of prescription opioid addiction

Individuals addicted to prescription painkillers are more likely to succeed in treatment with the aid of the medication buprenorphine-naloxone (Suboxone), report McLean Hospital and Harvard Medical School researchers in today's online edition of the Archives of General Psychiatry.

8 Nov 2011

Americans overdosing on prescription pain killers

According to figures released by the Centers for Disease Control and Prevention (CDC) 40 Americans die from prescription painkiller abuse each day. Overdoses of opioid prescription drugs now kill more people in the U.S. than do overdoses from heroin and cocaine combined the report says. Twelve million Americans say they abused prescription drugs in the last year.

2 Nov 2011

J&JPRD submits NUCYNTA ER sNDA to FDA for DPN associated neuropathic pain

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced today that it has submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for NUCYNTA ER (tapentadol) extended-release tablets, an oral analgesic, for the management of neuropathic pain associated with diabetic peripheral neuropathy in adults.

31 Oct 2011

FDA approves Pacira's EXPAREL for postsurgical pain management

Pacira Pharmaceuticals, Inc. announces that the U.S. Food and Drug Administration (FDA) has approved EXPAREL 1.3% for administration into the surgical site to produce postsurgical analgesia.

31 Oct 2011

Opioids News and Research

Further Reading

Study may help personalize pain medication management for sickle cell disease patients

Medical websites provide harmful information about postherpetic neuralgia treatments

Dramatic nationwide rise in opioid use for chronic abdominal pain

Combination of other opioids with methadone therapy can lead to overdose or fatal consequences

Naltrexone for problem gamblers

Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

Viewpoints: Questions of partisanship and timing could complicate Supreme Court's decision on health law

Researchers explore how design of chronic and acute pain trials might be improved

Opioid-dependent patients have worse outcomes before knee replacement surgery

Positive results from Alkermes VIVITROL addiction study

APS supports CDC's call for multifaceted approach to address prescription drug misuse

NIH announces results from first large scale study on treatment of prescription opioid addiction

QRxPharma receives FDA written acceptance for review of MoxDuo IR NDA

Racial/ethnic disparities among adolescents with substance-related disorders

QRxPharma receives date for US pain drug launch, pending approval

Link between heavy methamphetamine use and schizophrenia

First large-scale study to address treatment of prescription opioid addiction

Americans overdosing on prescription pain killers

J&JPRD submits NUCYNTA ER sNDA to FDA for DPN associated neuropathic pain

FDA approves Pacira's EXPAREL for postsurgical pain management

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

Latest News