Preclinical News and Research

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A new method for imaging the placenta in pregnant patients

A study published in Nature Biomedical Engineering details a novel method for imaging the placenta in pregnant patients as well as the results of a pilot clinical study.

16 Aug 2022

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science, a leader in automated generation of complex 3D cell models, and PhenoVista Biosciences, a top provider of custom imaging-based phenotypic assay services, have entered into a partnership to deliver high-content cell-based assay services for drug discovery.

From Inventia Life Science 16 Aug 2022

Report documents the detection of monkeypox virus in anal samples taken from asymptomatic MSM

A brief research report documents positive monkeypox virus PCR results found in anal samples taken from asymptomatic MSM (men who have sex with men).

16 Aug 2022

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

Researchers evidenced the presence of SARS-CoV-2 in the human brain, infecting astrocytes and impairing neuronal function and viability.

15 Aug 2022

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Scientists evaluate the role of CD8+ T-cells in vaccine protection against SARS-CoV-2 infection in rhesus macaques.

14 Aug 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Powerful injectable gel provides hope for preventing glioblastoma relapse

Like the hardiest weed, glioblastoma almost always springs back - usually within months after a patient's initial brain tumor is surgically removed.

8 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The University of Texas MD Anderson Cancer Center and TransCode Therapeutics, Inc. today announced a strategic alliance to advance TransCode's pipeline of RNA-targeted oncology therapeutic and diagnostic candidates.

2 Aug 2022

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

Researchers assessed the potential of nanosponges against SARS-CoV-2.

1 Aug 2022

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

The Alzheimer’s Association will present seven awards at the Alzheimer’s Association International Conference 2022, recognizing researchers for their varied expertise, noteworthy achievements and innovative contributions to the field of Alzheimer’s and dementia science.

1 Aug 2022

ACROBiosystems was titled 2022 CiteAb Awards protein supplier winner, gaining global scientific approval

Recently, ACROBiosystems won Cite Awards, being titled "the Winner of Protein Supplier to Watch in 2022".

From ACROBiosystems 1 Aug 2022

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Researchers review current developments in preclinical studies associated with recombinant ACE2 decoy receptors against coronaviruses.

31 Jul 2022

Novel algorithm identifies adverse drug events across the seven pediatric development stages

Side effects from pediatric drug treatment are responsible for nearly 10 percent of childhood hospitalizations, with nearly half of those being life-threatening. Despite the need to know more about these drugs and the adverse events they can have on children, little evidence is currently available.

28 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Repurposing an antipsychotic drug to treat various types of cancer

To treat some of the psychosis issues associated with Parkinson's disease, physicians often prescribe pimavanserin, an antipsychotic drug that acts within the brain to prevent hallucinations and delusions.

28 Jul 2022

Preclinical News and Research

A new method for imaging the placenta in pregnant patients

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Report documents the detection of monkeypox virus in anal samples taken from asymptomatic MSM

Study shows astrocytes as breeding grounds of SARS-CoV-2 during brain infection

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Azelastine nasal spray could decrease SARS-CoV-2 load

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Powerful injectable gel provides hope for preventing glioblastoma relapse

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

ACROBiosystems was titled 2022 CiteAb Awards protein supplier winner, gaining global scientific approval

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Novel algorithm identifies adverse drug events across the seven pediatric development stages

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Repurposing an antipsychotic drug to treat various types of cancer

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