Proliferation News and Research

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Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

Combination of radiotherapy and anti-hormone treatment can prevent recurrence of hormone-driven breast cancer

Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment, according to results from a trial that has followed 869 women for ten years.

26 Apr 2019

Cancer drugs reprogram genes in breast tumors to prevent endocrine resistance, finds study

Treating breast tumors with two cancer drugs simultaneously may prevent endocrine resistance by attacking the disease along two separate gene pathways, scientists at the University of Illinois found in a new study.

24 Apr 2019

Reviving the heart's regenerative capacities using microRNAs

Once the heart is fully formed, the cells that make up heart muscle, known as cardiomyocytes, have very limited ability to reproduce themselves. After a heart attack, cardiomyocytes die off; unable to make new ones, the heart instead forms scar tissue. Over time, this can set people up for heart failure.

23 Apr 2019

Study identifies possible therapeutic effects of curcumin on stomach cancer

Curcumin is widely used to impart color and flavor to food, but scientists have discovered that this yellow powder derived from the roots of the turmeric plant (Curcuma longa) can also help prevent or combat stomach cancer.

22 Apr 2019

Researchers are developing brand-new method to cure brain tumors

Scientists from Far Eastern Federal University in cooperation with colleagues from Blokhin Russian Cancer Research Center, Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors.

22 Apr 2019

Research sheds light on how hepatitis B virus establishes chronic infection

New research sheds light on how a hepatitis B viral protein stimulates the expansion of immune cells that impair antiviral responses, according to a study published April 18 in the open-access journal PLOS Pathogens by Haitao Guo of the Indiana University School of Medicine, Bin Wang and Jiming Zhang of Fudan University, and colleagues.

19 Apr 2019

Phasefocus to launch new cell imaging system with smart incubation technology

Phasefocus has secured additional investment as it prepares to launch the newest version of its flagship live cell imaging and analysis system, Livecyte™.

From Phase Focus Limited 19 Apr 2019

Molecular target UNC45A is essential for cancer cell proliferation and tumor growth

Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. It is especially promising when this protein is dispensable for the growth of normal cells.

19 Apr 2019

Scientists use NIR light and injected DNA nanodevice to guide stem cells to injury

What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process?

18 Apr 2019

Rutgers researchers identify new factor essential for maintaining stem cells in the brain and gut

The organs in our bodies house stem cells that are necessary to regenerate cells when they become damaged, diseased or too old to function.

17 Apr 2019

Outpatient healthcare providers inappropriately prescribe antibiotics to 40% of patients

Outpatient healthcare providers inappropriately prescribed antibiotics to 40 percent of patients in a major Veterans Affairs healthcare system, a higher figure than in previous studies examining outpatient antibiotic use, according to a new study appearing in the American Journal of Infection Control, the journal of the Association for Professionals in Infection Control and Epidemiology published by Elsevier.

17 Apr 2019

Japanese researchers explain how inflammation causes gastric tumors

In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly-identified pathogen.

16 Apr 2019

Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence.

15 Apr 2019

Potential new therapeutic approach identified for neuroblastoma tumors

Research led by Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease.

12 Apr 2019

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

Scientists discover central role of cell 'skeleton'

All cells possess a cytoskeleton which allows them to move and maintain their shape. However, scientists recently showed that a part of this cytoskeleton called branched actin is also essential to cell proliferation: this actin transmits information to cells about the space around them, environmental chemical messages and therefore on whether they should proliferate.

10 Apr 2019

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.

4 Apr 2019