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Immunotherapy before and after surgery benefits NSCLC patients

People with operable non-small cell lung cancers may fare better over the next few years by receiving immunotherapy treatments before and after surgery instead of only before surgery, according to a new analysis by Johns Hopkins Kimmel Cancer Center investigators.

9 Sep 2024

Major funding boost aims to advance research on bone metastasis in breast and prostate cancers

Breast Cancer Now and Prostate Cancer Research have joined forces to fund up to £600,000 of new research to tackle the spread of both cancers to the bones, known as bone metastasis.

6 Sep 2024

Tiny magnetic nanorobots show promise for treating brain aneurysms

Researchers have created nanoscale robots which could be used to manage bleeds in the brain caused by aneurysms.

6 Sep 2024

Researchers make breakthrough in predicting the prognosis of triple-negative breast cancer

Scientists at Huntsman Cancer Institute at the University of Utah (the U), the National Cancer Institute-designated cancer center for the Mountain West, have made a significant breakthrough in predicting the prognosis of triple-negative breast cancer (TNBC), a particularly aggressive disease.

5 Sep 2024

Researchers seek to revolutionize neurological disease treatment through intelligent biocomputing

With newly awarded funding from the National Science Foundation, researchers at the University of California, Irvine and the Keck School of Medicine of USC will seek to revolutionize the treatment of neurological diseases through intelligent biocomputing.

5 Sep 2024

Weight-loss surgery offers better control of high blood pressure compared to medications

People with obesity who underwent weight-loss surgery were more likely to control their high blood pressure over a 1-to-5 year follow-period compared to those who managed their high blood pressure with medications and lifestyle management, according to preliminary research to be presented at the American Heart Association's Hypertension Scientific Sessions 2024.

5 Sep 2024

Study finds early pancreatic cancer staging often inaccurate

Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new Cedars-Sinai Cancer study published in the peer-reviewed journal JAMA.

5 Sep 2024

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Semaglutide significantly reduces all-cause mortality in non-diabetic obese patients, particularly by lowering infection-related deaths during the COVID-19 pandemic. However, the study's findings should be interpreted with caution due to potential competing risks and unique pandemic circumstances.

5 Sep 2024

Long-term exposure to air pollution and noise associated with infertility risks

Long term exposure to fine particulate matter (PM2.5) air pollution is linked to a higher risk of infertility in men, whereas road traffic noise is linked to a higher risk of infertility in women over 35, finds a Danish study published by The BMJ today.

4 Sep 2024

Study uncovers key enzyme link between obesity and atrial fibrillation

A cellular link between obesity and atrial fibrillation - a heart condition that afflicts over 33 million people worldwide - presents a promising target for new therapies, researchers from the University of Illinois Chicago report.

4 Sep 2024

Breast cancer rises among Asian American and Pacific Islander women

Christina Kashiwada was traveling for work during the summer of 2018 when she noticed a small, itchy lump in her left breast.

4 Sep 2024

Lifestyle interventions in patients after colorectal cancer treatment

A recent RCT reveals the HEAL ABC intervention is feasible for 87% of colorectal cancer survivors, supporting healthy lifestyle changes and improved well-being.

4 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

An invasive strategy vs. optimal medical therapy alone after a non-ST-elevation myocardial infarction (NSTEMI) in older adults did not affect the combined risk of cardiovascular death or MI, although non-fatal MIs and subsequent revascularisation procedures were reduced, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

The SGLT2 inhibitor empagliflozin confers kidney-protective benefits and can therefore be given safely and effectively to patients when they are hospitalized for acute myocardial infarction (MI), a Mount Sinai-led global team of researchers has shown.

1 Sep 2024

Study links blood markers to long-term cardiovascular risk in women

Research supported by the National Institutes of Health has found that measuring two types of fat in the bloodstream along with C-reactive protein (CRP), a marker of inflammation, can predict a woman's risk for cardiovascular disease decades later.

1 Sep 2024

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to severe functional mitral regurgitation (FMR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

There was no difference in efficacy between transcatheter edge-to-edge repair (TEER) and surgery in patients with secondary mitral regurgitation (MR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Surgery News and Research

Immunotherapy before and after surgery benefits NSCLC patients

Major funding boost aims to advance research on bone metastasis in breast and prostate cancers

Tiny magnetic nanorobots show promise for treating brain aneurysms

Researchers make breakthrough in predicting the prognosis of triple-negative breast cancer

Researchers seek to revolutionize neurological disease treatment through intelligent biocomputing

Weight-loss surgery offers better control of high blood pressure compared to medications

Study finds early pancreatic cancer staging often inaccurate

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Long-term exposure to air pollution and noise associated with infertility risks

Study uncovers key enzyme link between obesity and atrial fibrillation

Breast cancer rises among Asian American and Pacific Islander women

Lifestyle interventions in patients after colorectal cancer treatment

A novel therapeutic option for HER2-positive extramammary Paget disease

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

Study reveals key genetic markers for early onset bicuspid aortic valve complications

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

Study links blood markers to long-term cardiovascular risk in women

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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