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CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

Human cells can change their original function to battle against diabetes

For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for diabetes patients.

14 Feb 2019

Use of liver grafts from older donors decreased despite better outcomes in recipients

More than 10 percent of patients waiting for a liver transplant die each year. This observational study looked at trends in the transplantation of livers from older donors and outcomes in recipients of these older livers from 2003 to 2016.

14 Feb 2019

Severe facial trauma victims can improve speech by face transplant surgery

A new case study out of New York University's Steinhardt School of Culture, Education, and Human Development finds that face transplant surgery in patients who have experienced severe facial trauma can improve speech production

13 Feb 2019

New bioengineered device enhances the production of T-cells

Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion of blood stem cells from a matched donor into the patient to 'reset' the blood and immune system.

12 Feb 2019

Antibody-based treatment could improve cure rate for blood and immune disorders

An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.

12 Feb 2019

Researchers to investigate light therapy as relief from painful side effect of cancer treatment

University at Buffalo researchers have received part of a $1.5 million grant to investigate light therapy as a replacement for prescription opioids in treating oral mucositis, painful ulcers and swelling in the mouth that result from chemotherapy and radiation treatment for cancer.

12 Feb 2019

Scientists uncover mechanism that makes aspergillus infection fatal

Researchers at the University of Jena in Germany have discovered how Aspergillus fumigatus suppresses immune defences to enable the infection to become fatal.

11 Feb 2019

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes.

11 Feb 2019

Blood cells could hold the key to aging

Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine.

8 Feb 2019

New blood drop emoji due to hit smartphone keyboards in the spring

Blood donors can soon use their time in the donation chair to let people know they are saving lives – using a new blood drop emoji.

8 Feb 2019

Leviticus Cardio and Jarvik Heart reveal novel wireless heart pump system

A groundbreaking piece of medical technology was revealed to the public today at the National Research Center for Cardiac Surgery in Astana, Kazakhstan. At a press conference held at the Center, top heart failure experts from around the world announced the successful implantation of FIVAD into a human.

7 Feb 2019

Powerful immune molecule silences barrel to protect transplanted organs from rejection

A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.

5 Feb 2019

Study uncovers new clues to lung transplant rejection

A lung transplant often remains the only option for many patients with end-stage lung disease, a condition that can be brought on by emphysema, pulmonary fibrosis, cystic fibrosis and other lung disorders.

4 Feb 2019

New clinical practice guideline on home oxygen therapy for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society's American Journal of Respiratory and Critical Care Medicine.

4 Feb 2019

A new approach towards future treatment of diabetes

It is said that the eyes are the window to the soul, but they may also open the door for discovering new ways to achieve immune tolerance to transplanted islets in type 1 diabetes, according to research from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine.

3 Feb 2019

Short anti-rejection therapy improves survival of transplanted pancreatic islets in diabetic animals

Transplanted pancreatic islets in diabetic animals can survive for a long period of time if the animals are treated with short anti-rejection therapy around the time of the transplant.

1 Feb 2019

Transplant News and Research

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

Newly developed stem cell technologies show promise for treating PD patients

Large-scale clinical trial begins to study liver transplantation between people with HIV

Human cells can change their original function to battle against diabetes

Use of liver grafts from older donors decreased despite better outcomes in recipients

Severe facial trauma victims can improve speech by face transplant surgery

New bioengineered device enhances the production of T-cells

Antibody-based treatment could improve cure rate for blood and immune disorders

Researchers to investigate light therapy as relief from painful side effect of cancer treatment

Scientists uncover mechanism that makes aspergillus infection fatal

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

Blood cells could hold the key to aging

New blood drop emoji due to hit smartphone keyboards in the spring

Leviticus Cardio and Jarvik Heart reveal novel wireless heart pump system

Powerful immune molecule silences barrel to protect transplanted organs from rejection

Study uncovers new clues to lung transplant rejection

New clinical practice guideline on home oxygen therapy for children

A new approach towards future treatment of diabetes

Short anti-rejection therapy improves survival of transplanted pancreatic islets in diabetic animals

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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