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Study can help spur beneficial lifestyle changes in patients to reduce Alzheimer's risk

Armed with new knowledge about how neurodegenerative diseases alter brain structures, increasing numbers of neurologists, psychiatrists and other clinicians are adopting quantitative brain imaging as a tool to measure and help manage cognitive declines in patients. These imaging findings can help spur beneficial lifestyle changes in patients to reduce risk for Alzheimer's disease.

5 Jun 2015

Scientists identify new agent to combat tuberculosis

According to figures of the World Health Organization, some 8.7 million people contracted tuberculosis in 2012 and this disease is fatal for approximately 1.3 million people throughout the world each year. One of the main problems is that the tuberculosis pathogens have become resistant to the antibiotics used to fight them.

5 Jun 2015

Finding could help researchers develop new methods to prevent cognitive decline in Alzheimer's disease

The process that allows our brains to learn and generate new memories also leads to degeneration as we age, according to a new study by researchers at MIT.

5 Jun 2015

Delay of gratification linked to white matter connectivity in the dorsal prefrontal cortex

The ability to delay gratification in chimpanzees is linked to how specific structures of the brain are connected and communicate with each other, according to researchers at Georgia State University and Kennesaw State University.

5 Jun 2015

Ibrutinib (IMBRUVICA) improves survival in treatment-naïve patients with chronic lymphocytic leukemia

Today, Pharmacyclics LLC, an AbbVie company, announced that ibrutinib (IMBRUVICA) improved progression-free survival (PFS; primary endpoint) and multiple secondary endpoints including overall survival (OS) and overall response rate (ORR) in treatment-naïve patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL, respectively) in the final analysis of the Phase III RESONATE™-2 (PCYC-1115) trial.

5 Jun 2015

WuXi AppTec, Fudan University partner for genomics database system

WuXi AppTec today announced a partnership with Fudan University to bring WuXi NextCODE's world-leading population human genomics database system and integrated research and clinical solutions to the Fudan-led Collaborative Innovation Center of Genetics and Development as an enterprise partner.

4 Jun 2015

Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

Rhythm announced today the initiation of two Phase 2 clinical trials focused on evaluating the safety and effectiveness of setmelanotide (RM-493), the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of Prader-Willi Syndrome (PWS) and POMC-null obesity.

4 Jun 2015

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that dosing has begun in a first-in-human Phase I clinical study of RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of microRNA-21 ("miR-21").

4 Jun 2015

University of Chicago scientists develop new technique to accurately measure epigenetic changes

One of the most widely used tools in epigenetics research - the study of how DNA packaging affects gene expression - is chromatin immunoprecipitation (ChIP), a technique that allows researchers to examine interactions between specific proteins and genomic regions. However, ChIP is a relative measurement, and has significant limitations that can lead to errors, poor reproducibility and an inability to be compared between experiments.

4 Jun 2015

Penn Medicine researchers explore primary player involved in T cell exhaustion

Sometimes even cells get tired. When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop 'T cell exhaustion,' becoming less effective and losing their ability to attack and destroy the invaders of the body.

4 Jun 2015

Novel strategy shows aptamer-based modular delivery of microRNA in endothelial, breast cancer cells

Researchers have shown that a novel delivery strategy can efficiently introduce a functional microRNA that has anti-cancer and angiogenic activities into two different types of cells--breast cancer cells to inhibit tumor growth and metastasis, and cells that line blood vessels to protect against atherosclerosis.

4 Jun 2015

Scientists make breakthrough in schizophrenia research

An international team of scientists led by Cardiff University researchers has provided the strongest evidence yet of what causes schizophrenia - a condition that affects around 1% of the global population.

4 Jun 2015

Scientists uncover why some people more prone to major depression

Scientists are beginning to unwrap the biology behind why some people are more prone to major depression and other psychiatric disorders than others when experiencing stressful life events. The researchers found that cellular activity in response to stress hormone receptor activation differs from individual to individual.

4 Jun 2015

U of T researchers uncover new insights on genetic causes of ALS

Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), which is also known as Lou Gehrig's disease. These findings could uncover a new way to detect a genetic predisposition to ALS before the disease strikes.

4 Jun 2015

Scientists produce strongest evidence yet of schizophrenia’s causes

3 Jun 2015

Manchester, UCL researchers discover new technique for treating polycystic kidney disease

A new technique for treating polycystic kidney disease has been identified by researchers at The University of Manchester and UCL.

3 Jun 2015

Majority of breast cancer patients unaware of the effect of double mastectomy

A survey of women with breast cancer found that nearly half considered having a double mastectomy. But of those who considered it, only 37 percent knew that the more aggressive procedure does not improve survival for women with breast cancer.

3 Jun 2015

UAB study finds how genetic variation in IIS/TOR molecular network may regulate variation in metabolism

New research from the University of Alabama at Birmingham finds genetic variants that occur in nature and lay the groundwork for future studies of diseases and treatments in humans.

3 Jun 2015

University of Adelaide research shows genetics play vital role in the cause of cerebral palsy

University of Adelaide researchers have discovered cerebral palsy has an even stronger genetic cause than previously thought, leading them to call for an end to unnecessary caesareans and arbitrary litigation against obstetric staff.

3 Jun 2015

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow out of control, eventually becoming cancerous.

3 Jun 2015

Genetic News and Research

Study can help spur beneficial lifestyle changes in patients to reduce Alzheimer's risk

Scientists identify new agent to combat tuberculosis

Finding could help researchers develop new methods to prevent cognitive decline in Alzheimer's disease

Delay of gratification linked to white matter connectivity in the dorsal prefrontal cortex

Ibrutinib (IMBRUVICA) improves survival in treatment-naïve patients with chronic lymphocytic leukemia

WuXi AppTec, Fudan University partner for genomics database system

Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

Regulus Therapeutics begins RG-012 Phase I clinical study for treatment of Alport syndrome

University of Chicago scientists develop new technique to accurately measure epigenetic changes

Penn Medicine researchers explore primary player involved in T cell exhaustion

Novel strategy shows aptamer-based modular delivery of microRNA in endothelial, breast cancer cells

Scientists make breakthrough in schizophrenia research

Scientists uncover why some people more prone to major depression

U of T researchers uncover new insights on genetic causes of ALS

Scientists produce strongest evidence yet of schizophrenia’s causes

Manchester, UCL researchers discover new technique for treating polycystic kidney disease

Majority of breast cancer patients unaware of the effect of double mastectomy

UAB study finds how genetic variation in IIS/TOR molecular network may regulate variation in metabolism

University of Adelaide research shows genetics play vital role in the cause of cerebral palsy

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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