Angiotensin Converting Enzyme 2 News and Research

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Biomarkers help tailor diuretic treatment for acute heart failure patients

Adrenomedullin activity predicts which acute heart failure patients are at the greatest risk of death without diuretic treatment post-discharge, according to late breaking research presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology.

26 May 2019

New device approved by FDA for treating patients with moderate-to-severe heart failure

The U.S. Food and Drug Administration today approved the Optimizer Smart system for treating patients with chronic, moderate-to-severe heart failure who are not suited for treatment with other heart failure devices such as cardiac resynchronization therapy to restore a normal timing pattern of the heartbeat.

22 Mar 2019

New guidelines on clinical use of life-saving antibiotics

An international panel of the foremost researchers on infectious disease and antimicrobials has formed new guidelines on the use of polymyxins, a class of antibiotics employed as a last resort to treat deadly, drug-resistant bacteria.

11 Mar 2019

Study sheds new light on left ventricular dysfunction in ischemic heart disease

Ischemic heart disease is a growing cause of heart failure owing to the increasing prevalence of diabetes, hypertension, and obesity.

17 Feb 2019

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor.

7 Feb 2019

Review highlights calcium handling mechanisms involved in reperfusion injury

Stroke and myocardial infarction (MI) are a significant cause of death and disability worldwide. However, over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion (percutaneous coronary intervention and cardiopulmonary bypass), the mortality of MI has declined dramatically.

20 Dec 2018

Heart failure patients with stronger hearts have more depressive symptoms, lower quality of life

Heart failure patients fall into two general categories: those with weaker hearts, and those with stronger, but stiffer hearts that continue to eject the normal volume of blood with every beat.

20 Nov 2018

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.

14 Sep 2018

Blood pressure lowering therapy and statins continue to improve survival in patients with hypertension

Blood pressure and cholesterol lowering drugs continue to improve survival in patients with hypertension after more than a decade, according to late breaking results from the ASCOT Legacy study presented at ESC Congress 2018 and published in The Lancet.

28 Aug 2018

Blood pressure medication slows enlargement of the aorta in patients with Marfan syndrome

Treatment with a drug to lower blood pressure slows enlargement (dilatation) of the aorta in children and young adults with Marfan syndrome, according to late breaking results from the AIMS trial presented today in a Hot Line Session at ESC Congress 2018.

28 Aug 2018

Taking vacations could prolong life, suggests new study

Taking vacations could prolong life. That's the finding of a 40-year study presented today at ESC Congress and accepted for publication in The Journal of Nutrition, Health & Aging.

28 Aug 2018

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

The antithrombin drug rivaroxaban does not reduce the risk of a composite endpoint of survival, myocardial infarction and stroke after an episode of worsening heart failure in patients with heart failure, sinus rhythm, and coronary artery disease, according to late breaking results from the COMMANDER HF trial presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in NEJM.

27 Aug 2018

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

A drug currently in clinical trials for treating symptoms of Parkinson's disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.

20 Jul 2018

Study suggests proteinuria lowering as important target in managing pediatric CKD

In a study of children with chronic kidney disease, blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression.

22 Jun 2018

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Clinical trial enrolment favors men, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. The study found that fewer women meet eligibility criteria for trials of heart failure medication.

28 May 2018

Weekend admissions linked to excess mortality risk among young heart attack patients

Young heart attack patients are twice as likely to die if they are admitted to hospital during the weekend compared to a weekday, according to an Italian study in more than 80,000 patients presented today at Acute Cardiovascular Care 2018.

5 Mar 2018

Study finds Ramadan fasting to be safe for heart failure patients

Ramadan fasting can be safe for patients with heart failure, according to research presented today at the 29th Annual Conference of the Saudi Heart Association, held 1 to 3 March in Riyadh, Saudi Arabia.

1 Mar 2018

Recommendations to prevent heart failure hospitalizations

Heart failure (HF) affects approximately 5.7 million adults in the United States according to the Centers for Disease Control and Prevention. If not properly managed, HF can lead to frequent hospitalizations.

10 Nov 2017

Study shows Healthy Days as valid method to evaluate overall population health

Humana Inc. today announced results from a study that found a relationship between patient-reported, health-related quality of life and multiple objective measures of health in elderly Medicare Advantage patients with chronic conditions.

28 Oct 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Angiotensin Converting Enzyme 2 News and Research

Biomarkers help tailor diuretic treatment for acute heart failure patients

New device approved by FDA for treating patients with moderate-to-severe heart failure

New guidelines on clinical use of life-saving antibiotics

Study sheds new light on left ventricular dysfunction in ischemic heart disease

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Review highlights calcium handling mechanisms involved in reperfusion injury

Heart failure patients with stronger hearts have more depressive symptoms, lower quality of life

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Blood pressure lowering therapy and statins continue to improve survival in patients with hypertension

Blood pressure medication slows enlargement of the aorta in patients with Marfan syndrome

Taking vacations could prolong life, suggests new study

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

Drug in clinical trials for Parkinson's disease offers hope for treating heart failure

Study suggests proteinuria lowering as important target in managing pediatric CKD

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Weekend admissions linked to excess mortality risk among young heart attack patients

Study finds Ramadan fasting to be safe for heart failure patients

Recommendations to prevent heart failure hospitalizations

Study shows Healthy Days as valid method to evaluate overall population health

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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