Bone News and Research

RSS

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Study reveals new approach for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds.

29 Apr 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

Novel plug-and-play multi-organ chip can be customized to the patient

Engineered tissues have become a critical component for modeling diseases and testing the efficacy and safety of drugs in a human context.

27 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Suboptimal treatment of hypothyroidism linked to worse hospital outcomes

Undertreatment with thyroid hormone replacement can put patients with hypothyroidism at risk for worse hospital outcomes, including longer length of stay and higher rates of readmission, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

26 Apr 2022

Calcium supplements may increase risk of death in older people with aortic valve stenosis

Calcium supplements, frequently given to older people to lessen the risk of brittle bones (osteoporosis) and fractures, are linked to a heightened risk of death among those with aortic valve stenosis, a progressive and potentially fatal condition, finds research published online in the journal Heart.

26 Apr 2022

Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats.

21 Apr 2022

UNIGE biologists discover a factor that explains breast cancer metastases to the bones

A team of biologists led by UNIGE has discovered, for breast cancer, a factor that explains the spread of metastases to the bones.

21 Apr 2022

Study examines vitamin D and COVID-19 media coverage in the U.K.

A new study investigates the relationship between COVID-19 and vitamin D that has been presented in traditional media sources like U.K. newspapers.

20 Apr 2022

Advancements in HIV science

As far as viruses go, human immunodeficiency virus (HIV) is quite simple. About 100,000 times smaller than a red blood cell, the virus expresses just a dozen proteins, yet it can establish a lifelong infection that, if left untreated, causes acquired immunodeficiency syndrome (AIDS) and death.

20 Apr 2022

Autonomous robot performs laparoscopic soft tissue surgery with minimal assistance from a surgeon

What if your next surgery was planned and performed by a robot? A team at Johns Hopkins University is working to turn this idea into reality.

20 Apr 2022

Most infants enrolled in WIC may not be getting the suggested daily amount of vitamin D, finds study

Most infants enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children, also known as WIC, are likely not getting the recommended daily amount of vitamin D, according to new research from the University of Georgia.

20 Apr 2022

Researchers reveal possible way to treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

19 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Racial disparities after hip and knee replacement reduced by a "bundled care" Medicare program

A "bundled care" Medicare program to improve care for patients undergoing hip or knee replacement surgery has led to reductions in some outcome disparities for Black compared with White patients, suggests a study in The Journal of Bone & Joint Surgery.

18 Apr 2022

When symptoms linger for weeks, is it long covid?

Many Americans are discovering that recovering from covid-19 may take weeks or even months longer than expected, leaving them with lingering symptoms like intense fatigue or a racing pulse. But does that mean they have what's known as long covid?

13 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

Bone News and Research

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Study reveals new approach for engineering stable articular cartilage

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Novel plug-and-play multi-organ chip can be customized to the patient

Penn scientists discover how one inflammatory disorder increases susceptibility to another

Suboptimal treatment of hypothyroidism linked to worse hospital outcomes

Calcium supplements may increase risk of death in older people with aortic valve stenosis

Dual release microparticle system promotes cranial bone defect healing

UNIGE biologists discover a factor that explains breast cancer metastases to the bones

Study examines vitamin D and COVID-19 media coverage in the U.K.

Advancements in HIV science

Autonomous robot performs laparoscopic soft tissue surgery with minimal assistance from a surgeon

Most infants enrolled in WIC may not be getting the suggested daily amount of vitamin D, finds study

Researchers reveal possible way to treat newborns with rare genetic lung condition

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

Racial disparities after hip and knee replacement reduced by a "bundled care" Medicare program

When symptoms linger for weeks, is it long covid?

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News