Clinical Trial News and Research

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Precision medicine doubles progression-free survival in young cancer patients

Cancer is the leading cause of disease-related death in children in most developed countries, and at least a quarter of these patients are diagnosed with aggressive high-risk or relapsed cancers, with an expected five-year survival rate of less than 30%.

31 May 2024

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress were more likely than their study peers to experience worse invasive disease-free survival (iDFS) and worse overall survival (OS).

31 May 2024

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

The novel anti-CD19 autologous chimeric antigen receptor (CAR) T cell therapy obecabtagene autoleucel (obe-cel) achieved durable remissions in 40% of patients with relapsed or refractory B-ALL without a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX clinical trial presented today by Elias Jabbour, M.D., professor of Leukemia.

31 May 2024

Eye-tracking technology offers earlier, more accurate autism diagnosis

Nearly 3% of all children in the United States are diagnosed with autism, according to the Centers for Disease Control and Prevention.

31 May 2024

Radiomics imaging analysis can effectively forecast hearing status of vestibular schwannoma patients

A recent study demonstrates that radiomics imaging analysis can effectively forecast the hearing status of patients with vestibular schwannoma patients.

31 May 2024

New mobile app shows dramatic success in smoking cessation

A new mobile application, developed under the leadership of researchers from the University of Oulu, Finland, has proven to be an effective aid for long-term smokers attempting to quit.

31 May 2024

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Researchers at Wake Forest University of School of Medicine have received a five-year, $1.5 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, to study bone microarchitecture in patients following bariatric surgery.

30 May 2024

Study examines the cost-effectiveness of a targeted immunotherapy for lung cancer

Many countries with national healthcare systems or payers such as insurance companies use cost-effectiveness analyses to decide whether to cover new medicines, balancing treatment costs with potential health benefits.

30 May 2024

Snap, track, eat: Taking photos of food could be key to better diets

New Curtin University research reveals taking pictures of food isn't just content for our social media feeds, but could be the key to improving people's diets.

30 May 2024

BRCA1 testing during prenatal care could prevent cancer, save lives

Harmful variants in the BRCA1 gene greatly increase a person's lifetime risk of developing breast, ovarian and pancreatic cancers, but most people are unaware they are carriers.

30 May 2024

Early peanut consumption slashes allergy risk by 71%, landmark study finds

A recent study published in NEJM Evidence found that feeding children peanut products regularly from infancy to age five reduced the rate of peanut allergy in adolescence by 71%, providing long-term prevention through early allergen consumption

29 May 2024

New type of immunotherapy shows promising preclinical results against osteosarcoma

A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Vaccination remains crucial for preventing avian influenza spread, says study

Vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains.

29 May 2024

Study finds kidney complications following heart failure hospitalization

In a study of Medicare beneficiaries, researchers from Brigham and Women's Hospital found that one year after hospitalization for heart failure, 6 percent of patients had progressed to dialysis.

29 May 2024

Psychoactive drugs are having a moment. The FDA will soon weigh in.

Lori Tipton is among the growing number of people who say that MDMA, also known as ecstasy, saved their lives.

29 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Automated text reminders boost mental health for health care workers

Health care workers have reported spikes in feeling burnt out in the time since the COVID-19 pandemic began, with nearly half saying it took a toll in 2022 compared to 32 percent in 2018.

28 May 2024

Clinical Trial News and Research

Precision medicine doubles progression-free survival in young cancer patients

Stress and pain linked to worse outcomes in HER2-positive breast cancer patients

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

Eye-tracking technology offers earlier, more accurate autism diagnosis

Radiomics imaging analysis can effectively forecast hearing status of vestibular schwannoma patients

New mobile app shows dramatic success in smoking cessation

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Study examines the cost-effectiveness of a targeted immunotherapy for lung cancer

Snap, track, eat: Taking photos of food could be key to better diets

BRCA1 testing during prenatal care could prevent cancer, save lives

Early peanut consumption slashes allergy risk by 71%, landmark study finds

New type of immunotherapy shows promising preclinical results against osteosarcoma

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Vaccination remains crucial for preventing avian influenza spread, says study

Study finds kidney complications following heart failure hospitalization

Psychoactive drugs are having a moment. The FDA will soon weigh in.

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

Study highlights a dietary strategy for health improvement and weight management

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Automated text reminders boost mental health for health care workers

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