Polymerase News and Research

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Synthetic SARS-CoV-2 vs. SARS-CoV-2

Though vaccination efforts are underway in most countries, there are still limited options for treating COVID-19. Now, researchers at Penn State designed a new COVID-19 therapy that uses a defective synthetic version of the SARS-CoV-2 virus to interfere with the actual virus's replication.

23 Aug 2021

SARS-CoV-2 alpha variant exhibits enhanced household transmission

In a recent study, the transmission rate of wildtype and the Alpha variant of SARS-CoV-2 through households is tracked.

23 Aug 2021

The emergence and spread of the SARS-CoV-2 Lambda (B.1.621) variant

A new study details the genomic characteristics and descent of a SARS-CoV-2 variant of interest.

23 Aug 2021

New study identifies novel compound as promising pan-coronavirus drug candidate

A recent study describes a novel compound with frameshifting capability against MERS-CoV, inhibiting viral propagation within infected cells.

23 Aug 2021

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Aug 2021

Scientists propose innovative method to test the effectiveness of coronavirus medicines

South Ural State University scientists have proposed an innovative method for testing the effectiveness of medicines for coronavirus. According to the researchers, it is necessary to focus on the maximum coincidence of the ligand and the receptor. The results of the work have been published in the highly-rated journal "Molecules"(Q1).

18 Aug 2021

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

A new study suggests a new coronavirus test developed by scientists from the University of Washington and the Brotman Baty Institute for Precision Medicine produces faster and more sensitive results than conventional PCR tests to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA.

18 Aug 2021

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

The safety, immunogenicity, and efficacy of the vaccines in adolescents are largely unknown. Now, a new study published in the New England Journal of Medicine evaluates the safety and efficacy of the mRNA-1273 vaccine in adolescents (12-17 years of age).

16 Aug 2021

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

A recent study discusses how New Zealand rapidly employed real-time genomics to contain new COVID-19 cases.

16 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

A team of Massachusetts General Hospital researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.

12 Aug 2021

Ten-fold reduced risk of workplace SARS-CoV-2 infection in seropositive essential workers

A reassuring new study supports the opening of workplaces to seropositive workers in view of the extremely low risk of reinfection observed in this cohort.

11 Aug 2021

UC San Diego’s wastewater surveillance system enables early detection of most COVID-19 cases

People infected with SARS-CoV-2, the virus that causes COVID-19, are known to shed it in their stool, even if they aren't experiencing any symptoms.

11 Aug 2021

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

The coronavirus disease 2019 (COVID-19) has been thought to spread primarily when an infected person coughs or sneezes, but little is known about its transmissibility through activities such as breathing, talking, and singing.

11 Aug 2021

Emerging biosensing technologies could revolutionize the diagnosis of neonatal sepsis

Sepsis in newborn infants can be fatal. Early diagnosis is thus key to effectively manage the infection. Conventional diagnostic methods are, however, time-consuming.

11 Aug 2021

Researchers employ artificial intelligence models for image-based detection of COVID-19

Medical imaging has long been a vital tool for the diagnosis and prognostic assessments of many diseases. In recent years, the use of artificial intelligence models has been used in conjunction with this imaging to augment their diagnostic capabilities.

11 Aug 2021

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

A new study finds that heavy alcohol drinking is associated with an increase in the number of COVID-19 cases among American college students.

10 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

A new study describes the structure of a crucial enzyme present in SARS-CoV-2.

8 Aug 2021

Researchers develop a novel process for producing pure RNA

Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA.

6 Aug 2021

Polymerase News and Research

Synthetic SARS-CoV-2 vs. SARS-CoV-2

SARS-CoV-2 alpha variant exhibits enhanced household transmission

The emergence and spread of the SARS-CoV-2 Lambda (B.1.621) variant

New study identifies novel compound as promising pan-coronavirus drug candidate

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Scientists propose innovative method to test the effectiveness of coronavirus medicines

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

Real-time genomics to track SARS-CoV-2 help contain transmission in New Zealand

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

Ten-fold reduced risk of workplace SARS-CoV-2 infection in seropositive essential workers

UC San Diego’s wastewater surveillance system enables early detection of most COVID-19 cases

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

Emerging biosensing technologies could revolutionize the diagnosis of neonatal sepsis

Researchers employ artificial intelligence models for image-based detection of COVID-19

High alcohol consumption increases risk of SARS-CoV-2 infection, finds US student study

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

Researchers develop a novel process for producing pure RNA

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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