Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation grant, and the results were published in Nature Methods.

28 Sep 2018

TINY cancer detection device shows promise as point-of-care detector of KSHV

Its name is an acronym used to convey its size, but researchers at Cornell Engineering and Weill Cornell Medicine are hoping their hand-held cancer detection device's impact in the developing world is anything but small.

21 Sep 2018

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Applied DNA Sciences Inc. announced today that LineaRx, Inc., its wholly-owned subsidiary focused on next-generation biotherapeutics, has signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L., biotechnology companies focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal markets, respectively.

20 Sep 2018

NUS researchers develop new device for quick and accurate screening of diseases

A multidisciplinary team of researchers at the National University of Singapore has developed a portable, easy-to-use device for quick and accurate screening of diseases.

18 Sep 2018

Researchers develop new DNA-based test to detect trace amounts of peanuts in foods

For people with severe peanut allergies, eating even miniscule amounts of the legume can trigger anaphylaxis --- a life-threatening condition characterized by dizziness, breathing difficulties and, sometimes, loss of consciousness.

5 Sep 2018

Two thyroid medications recalled by FDA

The United States Food and Drug Administration (FDA) have announced the recall of two thyroid medications due to issues with their ingredients.

16 Aug 2018

Nalco Water's molecular-based test for Legionella provides much faster results than current methods

Nalco Water, an Ecolab company, has introduced a molecular-based test for Legionella that provides results 14-times faster than current culture testing methods to help building and cooling tower operators manage public health risks from the waterborne pathogen.

2 Aug 2018

New method tags breast implants with tomato DNA to prevent counterfeiting

For years, a French company sold breast implants made of cheap industrial silicone components. Headline news when it broke in 2010, this scandal is still keeping the courts busy today.

2 Aug 2018

Co-Diagnostics obtains CE mark approval for Logix Smart MTB Test

Co-Diagnostics, Inc., a molecular diagnostics company with a unique, proprietary platform for the development of molecular diagnostic tests, announced today that its Logix Smart™ MTB Test has obtained CE mark approval, the principle regulatory clearance allowing the test to be sold as an in vitro diagnostic for the diagnosis of tuberculosis in European Union states and other markets that accept a CE-IVD mark as valid regulatory approval.

25 Jul 2018

Improved methods to measure enterococci concentrations in recreational water

The concentration of enterococci, bacteria that thrive in feces, has long been the federal standard for determining water quality.

16 Jul 2018

Rethinking current method paves way for new, personalized cancer diagnostics

All diseases have a genetic component. Advances in understanding the genetic mechanisms behind these disease enables the development of early diagnostic tests, new treatments, or interventions to prevent disease onset or minimize disease severity.

28 Jun 2018

Studies provide insight into molecular changes prior to onset of arthritis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions.

18 Jun 2018

Scientists develop method to determine metabolic activity of neural networks

During the last decade, neurobiologists's attention has been focused on the study of the functioning of neural networks rather than single nerve cells.

14 Jun 2018

Scientists develop artificial intelligence platform to diagnose many diseases

A platform that can diagnose several diseases with a high degree of precision using metabolic markers found in patients' blood has been developed by scientists at the University of Campinas in Brazil

13 Jun 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018