Efficacy News and Research

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A new age-related macular degeneration discovery

Scientists have won a major battle in the fight against age-related macular degeneration, or AMD, a blinding eye disease that affects millions of people.

21 Feb 2008

Doctors in the United States say yes to marijuana

Doctors in the United States have given their endorsement for marijuana to be used for medical purposes.

17 Feb 2008

New non-invasive imaging method for diagnosing osteoarthritis

Researchers at New York University and Tel Aviv University have developed a non-invasive imaging method that can be used to diagnose and monitor a number of diseases, including osteoarthritis and inter-vertebral disc degeneration, in their early stages.

12 Feb 2008

Alpha-linolenic acid good for dry eye syndrome

Research conducted by Massachusetts Eye and Ear Infirmary (MEEI) Cornea Service Director and Harvard Medical School Professor Reza Dana, M.D., M. Sc., MPH, and colleagues at the Schepens Eye Research Institute have found for the first time that topical drop application of alpha-linolenic acid (ALA) led to a significant decrease in clinical signs of dry eye syndrome (DES) in animal models.

12 Feb 2008

Benefit of removal of the ovaries differs between women with BRCA1 and BRCA2 mutations

The surgical removal of the ovaries has been widely adopted as a cancer-risk-reducing strategy for women with either BRCA1 or BRCA2 mutations.

12 Feb 2008

$1-year results of bronchial thermoplasty in refractory asthma$

1-year results of bronchial thermoplasty in refractory asthma

Asthmatx, Inc. has announced the publication of data from the Research in Severe Asthma (RISA) Trial of bronchial thermoplasty in the American Journal of Respiratory and Critical Care Medicine (AJRCCM, 2007; 176:1185-1191).

12 Feb 2008

Amantadine and rimantadine for influenza A in children and the elderly

The antiviral drug amantadine can prevent some cases of influenza in children, and the related medication rimantadine can reduce fever in youngsters who have the flu, according to a new review of evidence.

8 Feb 2008

Novel drug shows promise in limiting heart attack damage

A novel drug designed to lessen muscle damage from a heart attack has passed initial safety tests at the Duke Clinical Research Institute.

8 Feb 2008

Review of psychosocial quit-smoking interventions for patients with coronary heart disease

Psychosocial interventions like counseling, telephone support and self-help materials can assist heart disease patients who are trying to give up cigarettes, but the most successful cessation treatments last a month or more, according to a new review of studies.

8 Feb 2008

Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells

Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells.

7 Feb 2008

Half of patients undergoing cerebrovascular stent placement do not respond well to clopidogrel

A study by researchers at Rush University Medical Center, published in the February issue of the American Journal of Neuroradiology, finds that half of patients undergoing cerebrovascular stent placement did not respond well to clopidogrel.

7 Feb 2008

U.S. FDA approval of generic Fosamax

The U.S. Food and Drug Administration today approved the first generic versions of Fosamax (alendronate sodium tablets), used to treat osteoporosis, a condition that causes thinning and weakening of a person's bones.

6 Feb 2008

Australian gene test opens door to personalised care

Australian researchers have led a study published in the New England Journal of Medicine that shows a simple blood test can allow doctors to predict which HIV patients will have a side effect, known as a hypersensitivity reaction, to a particular medication before it is prescribed.

6 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

New vaccine for malaria under trial

Trials are underway, funded by the Wellcome Trust, for a new vaccine to combat the most deadly form of malaria.

5 Feb 2008

The obesity epidemic - does the evidence stack up?

Last week, the UK health secretary declared that we are in a grip of an obesity epidemic, but does the evidence stack up? Researchers in this week's BMJ debate the issue.

5 Feb 2008

New FDA advisory on Chantix (varenicline)

The U.S. Food and Drug Administration (FDA) has issued a Public Health Advisory to alert health care providers, patients, and caregivers to new safety warnings concerning Chantix (varenicline), a prescription medication used to help patients stop smoking.

5 Feb 2008

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder that can cause uncontrolled bleeding.

5 Feb 2008

Study suggests Risperidone long-acting injection combined with standard treatment helped delay time to relapse in patients with bipolar disorder

Patients with frequently relapsing bipolar disorder had a significant delay in the time to an initial relapse when risperidone long-acting injection (RLAI) was combined with standard treatment, according to a new study. The study compared patients who received RLAI and standard treatment to those who received standard treatment combined with placebo.

4 Feb 2008

FDA approves only once-daily inhaled corticosteroid for children

Schering-Plough Corporation has announced that the U.S. Food and Drug Administration (FDA) has approved ASMANEX TWISTHALER 110 mcg (mometasone furoate inhalation powder) for the maintenance treatment of asthma as a preventive therapy in patients 4 to 11 years of age.

4 Feb 2008