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Millennium submits VELCADE sNDA to FDA to add OS data for previously untreated multiple myeloma

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced the submission of a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration for VELCADE® (bortezomib) for injection to add overall survival data after a five-year follow up to the product label.

20 Jul 2011

Obesity in kids reaches extreme levels

According to a Victoria's top childhood obesity experts, toddlers are becoming so obese they need hospital treatment and 10-year-olds so overweight they risk heart disease. This comes from Dr Matt Sabin, co-head of the Royal Children's Hospital weight management clinic who labeled Victoria's obesity epidemic as extreme. He said he often saw three-year-olds weighing 35kg - more than double their healthy weight - and 15-year-olds tipping the scales at up to 200kg.

18 Jul 2011

Scientists analyze structural changes in calcium channels caused by Timothy-mutation

The human genome encodes 243 voltage-gated ion channels. Mutations in calcium channels can cause severe inherited diseases such as migraine, night blindness, autism spectrum disorders and Timothy syndrome, which leads to severe cardiovascular disorders.

15 Jul 2011

Study: Overall awareness about eye health lower among ethnic Americans

The results of recent, comprehensive research supported by Transitions Optical revealed that the majority of Americans are not taking the proper steps to care for the health of their eyes, and that awareness of both short- and long-term effects of UV exposure on vision is remarkably low.

15 Jul 2011

IQWiG finds no differences between two treatment strategies for type 2 diabetes

Whether patients with type 2 diabetes mellitus benefit from attempts to lower their blood glucose levels to near-normal levels through treatment remains an unanswered question. The studies currently available provide indications of a benefit but also of potential harm.

15 Jul 2011

Novel bionic eyes for the blind in the making

British scientists have developed the first pair of bionic glasses that could help thousands of legally blind people. These glasses using tiny cameras and software technology from video games, alert the wearer to objects in their surroundings using flashing lights.

14 Jul 2011

Study demonstrates how unconscious brain continues to process information

Brain damage can cause significant changes in behaviour, such as loss of cognitive skills, but also reveals much about how the nervous system deals with consciousness. New findings reported in the July 2011 issue of Elsevier's Cortex demonstrate how the unconscious brain continues to process information even when the conscious brain is incapacitated.

14 Jul 2011

Patient-centered medical home boosts diabetes outcomes, health

A health-care delivery model called patient-centered medical home (PCMH) increased the percentage of diabetes patients who achieved goals that reduced their sickness and death rates, according to health researchers.

14 Jul 2011

African-Americans with glaucoma have higher oxygen levels than Caucasians

Measuring oxygen during eye surgery, investigators at Washington University School of Medicine in St. Louis have discovered a reason that may explain why African-Americans have a higher risk of glaucoma than Caucasians.

12 Jul 2011

Maternal smoking during pregnancy causes serious birth defects

To dispel any uncertainty about the serious harm caused by smoking to babies and pregnant women, the first-ever comprehensive systematic review of all studies over the past 50 years has established clearly that maternal smoking causes a range of serious birth defects including heart defects, missing/deformed limbs, clubfoot, gastrointestinal disorders, and facial disorders.

12 Jul 2011

Drug resistant gonorrhea discovered

Japanese scientists have found a superbug strain of gonorrhea that’s resistant to all available antibiotics. This can pose a threat to public health worldwide, infectious disease experts say.

11 Jul 2011

Ivermectin cream demonstrates activity against head lice eggs

In a study sponsored by Topaz Pharmaceuticals Inc., a privately held specialty pharmaceutical company, scientists from the University of Massachusetts, Amherst presented data showing that a 0.5% ivermectin (IVM) cream formulation was active against lice eggs from permethrin resistant head lice.

11 Jul 2011

Researchers identify new antibiotic-resistant gonorrhea strain

An international research team has discovered a strain of gonorrhea resistant to all currently available antibiotics. This new strain is likely to transform a common and once easily treatable infection into a global threat to public health.

11 Jul 2011

MSU professor focuses on new formulation for old drug to treat parasitic diseases

With the help of another $2 million in funding from the Bill & Melinda Gates Foundation, researchers are moving closer to setting up human clinical trials for a reformulated drug that could be the linchpin of treatment efforts against two debilitating tropical diseases.

11 Jul 2011

Researchers discover how genetic mutations cause rare human diseases

Researchers at the University of California, San Francisco and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.

11 Jul 2011

Pregnant women face higher risk of stroke

High blood pressure during pregnancy is a leading cause of maternal and fetal mortality worldwide.

8 Jul 2011

Mass administration of common anti-parasitic is possible new tool in fight against malaria

Ivermectin - an inexpensive, common medication already being used in Africa to treat roundworms that cause river blindness and parasites that cause elephantitis - could also be used to kill mosquitoes carrying malaria parasites, potentially "provid[ing] another useful weapon in the armory against a disease that kills around 800,000 a year, most of them small children and pregnant women," the Guardian's "Global Health Blog" reports (Boseley, 7/6).

8 Jul 2011

AHAF awards 22 new grants to scientists worldwide for innovative vision research

The American Health Assistance Foundation (AHAF), a nonprofit organization with a history of funding cutting-edge research on age-related diseases, announced today that it has awarded 22 new grants totaling nearly $2.2 million to scientists worldwide who are studying glaucoma and macular degeneration. The two conditions are the leading causes of irreversible vision loss and blindness in the U.S.

8 Jul 2011

Heartworm medication Ivermectin prevents malaria transmission in Africa

A cheap, common heartworm medication that is already being used to fight other parasites in Africa could also dramatically interrupt transmission of malaria, potentially providing an inexpensive tool to fight a disease that kills almost 800,000 people each year, according to a new study published in the July edition of the American Journal of Tropical Medicine and Hygiene.

7 Jul 2011

Study provides information about trends in obesity, public health implications

Researchers out of Arizona State University recently published an article in the American Journal of Public Health titled "Shared Norms and Their Explanation for the Social Clustering of Obesity". It looked at why obesity seems to be common in some families and groups of friends.

7 Jul 2011