Clinical Trial News and Research

RSS

Does reducing leisure-time screen media use improve mental health among children and adolescents?

Researchers investigated whether reducing the use of screen media for leisure improves mental health in adolescents and children.

17 Jul 2024

Nighttime resistance exercise 'activity breaks' may boost sleep duration, study finds

Resistance exercise 'activity breaks' at night may improve sleep length, suggest the findings of a small comparative study published in the open access journal BMJ Open Sport & Exercise Medicine.

17 Jul 2024

UCLA investigators receive $800,000 grant to treat and prevent aggressive kidney cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have received an $800,000 grant from the V Foundation to find new ways to treat and prevent a severe form of kidney cancer associated with a hereditary syndrome caused by mutations in the fumarate hydratase (FH) gene.

16 Jul 2024

UIC researchers explore digital tools to personalize depression treatment

New research at the University of Illinois Chicago is testing whether digital tools can help predict which patients with depression will benefit from specific treatments and help deliver those treatments to them on demand.

16 Jul 2024

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

An article published in the journal Cell describes a study that enabled a group of researchers to discover how SARS-CoV-2 evades the cytotoxic immune response by identifying a protein called ORF6 that is a key factor in this mechanism.

16 Jul 2024

Daily supplement may help preserve vision in people with late-stage dry AMD

In a new analysis of data, researchers at the National Institutes of Health (NIH) have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people with late-stage disease preserve their central vision.

16 Jul 2024

Early detection of specific microRNAs may help predict preeclampsia in pregnant women

Preeclampsia (PE) is a significant contributor to the increase in maternal morbidity and mortality worldwide, with particularly alarming numbers in the United States, where it affects about 2–8% of pregnancies, resulting in premature birth with associated morbidities for their infants as well.

16 Jul 2024

UChicago expands microbiome research capabilities with new manufacturing facility

The Duchossois Family Institute (DFI) at the University of Chicago can manufacture clinical-grade encapsulated bacteria – catalyzing opportunities to better understand the microbiome and its myriad of roles in human health.

16 Jul 2024

Triad of immune cells key to successful cancer immunotherapy, study finds

There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully - completely eliminating or greatly reducing cancer in particular patients - other times they don't work at all. It's a mystery.

15 Jul 2024

Cannabigerol shows promise in reducing anxiety and enhancing memory without side effects

Researchers at Washington State University found that cannabigerol (CBG) reduces anxiety and improves verbal memory without causing intoxication or impairments in healthy adults.

15 Jul 2024

Enhancing family-based treatment for anorexia nervosa: The role of intensive parental coaching

A study opens in new tab/window in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP)opens in new tab/window, published by Elsevier, investigated adaptive treatment for Anorexia Nervosa (AN), a serious psychiatric disorder with high morbidity and mortality.

15 Jul 2024

Consumer wearable devices provide clinical information similar to hospital assessment of heart disease

Monitoring of heart rate and physical activity using consumer wearable devices was found to have clinical value for comparing the response to two treatments for atrial fibrillation and heart failure.

15 Jul 2024

Long-term, 30-year CVD risk may help inform therapy for stage 1 hypertension

A comparison of two risk prediction tools used to calculate an individual's risk of developing cardiovascular disease (CVD) suggests that the long-term, 30-year risk should be considered in addition to the short-term, 10-year risk to help inform when to begin medication therapy for stage 1 hypertension, or high blood pressure, according to new research published today in Hypertension, an American Heart Association journal.

15 Jul 2024

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

15 Jul 2024

Testing the effectiveness of youth activism as a mental health intervention

Three hundred Black and Latinx teens in Chicago will be recruited to participate in the first clinical trial to measure the potential health benefits of youth-driven racial justice activism. The five-year study, funded by a $3.8 million grant from the National Institute on Minority Health and Health Disparities, will assess whether activism can lower depression symptoms in minoritized teens, as well as alter physiological factors known to be increased with exposure to racism, such as blood pressure and markers of stress and inflammation in the blood.

13 Jul 2024

New option emerges for managing stress urinary incontinence

An investigational medication designated TAS-303 shows efficacy and safety in treatment of women with stress urinary incontinence (SUI), reports a placebo-controlled clinical trial in the August issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

12 Jul 2024

Cellular immunotherapy offers hope for solid tumors

Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health (NIH) genetically engineered normal white blood cells, known as lymphocytes, from each patient to produce receptors that recognize and attack their specific cancer cells.

12 Jul 2024

Clinical Trial News and Research

Does reducing leisure-time screen media use improve mental health among children and adolescents?

Nighttime resistance exercise 'activity breaks' may boost sleep duration, study finds

UCLA investigators receive $800,000 grant to treat and prevent aggressive kidney cancer

UIC researchers explore digital tools to personalize depression treatment

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

Daily supplement may help preserve vision in people with late-stage dry AMD

Early detection of specific microRNAs may help predict preeclampsia in pregnant women

UChicago expands microbiome research capabilities with new manufacturing facility

Triad of immune cells key to successful cancer immunotherapy, study finds

Cannabigerol shows promise in reducing anxiety and enhancing memory without side effects

Enhancing family-based treatment for anorexia nervosa: The role of intensive parental coaching

Consumer wearable devices provide clinical information similar to hospital assessment of heart disease

Long-term, 30-year CVD risk may help inform therapy for stage 1 hypertension

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Testing the effectiveness of youth activism as a mental health intervention

New option emerges for managing stress urinary incontinence

Cellular immunotherapy offers hope for solid tumors

New tech shows promise for mental wellbeing

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Life Science Microscopy (2nd Edition)

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology