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Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

21 Mar 2016

Study: Conservative care could be a reasonable choice for selected kidney failure patients

A new study found no significant survival advantage among elderly kidney failure patients who chose dialysis over conservative management. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology, indicate that conservative care may be a reasonable choice for selected older patients.

18 Mar 2016

Sodium MRI could provide more detailed picture of tissue health and disease

MRI experts at The University of Nottingham win £1m grant to adapt scanning techniques to pick up sodium in the body. The research could lead to much more detailed MRI scans in the future with significant improvements to the diagnosis and treatment of many diseases.

18 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

On World Kidney Day, leading experts from the European ADPKD Forum today issue a collaborative letter to over 350 European decision makers (European Parliament, European Commission, Council representatives) celebrating the year one progress of the Brussels Declaration on ADPKD, while calling for urgent backing from policy makers to reduce the widespread inequalities and variations in care that remain.

10 Mar 2016

World Kidney Day 2016 focuses on children

On Thursday March 10th we are celebrating the 11th edition of World Kidney Day (WKD), a joint initiative organized by the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF).

10 Mar 2016

Pioneering progress on ADPKD: an interview with Tess Harris

ADPKD is a chronic, progressive and inherited kidney disease characterized by fluid-filled cysts that develop in the kidneys and other organs. It is the most common inherited kidney disease, and affects millions worldwide.

10 Mar 2016

Renal risk factors for NA-treated HBV patients identified

A South Korean research team has identified several clinical and medical factors associated with renal function decline in patients with chronic hepatitis B virus infection treated with oral nucleos(t)ide analogues.

10 Mar 2016

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).

10 Mar 2016

Physicians miss opportunities for detection and management of people with prediabetes

Less than one-quarter of patients who met the criteria for prediabetes received drug or lifestyle modification treatment from their primary care physician, according to University of Florida researchers, who say the findings indicate physicians are missing opportunities for diabetes prevention.

9 Mar 2016

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Cells collected noninvasively from the urine of preterm infants may lead to breakthroughs in regenerative kidney repair for patients with kidney disease and injury, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

4 Mar 2016

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults (Medicare beneficiaries) who are not on dialysis.

27 Feb 2016

Scientists reveal underlying mechanism for formation and growth of epithelial tubes

A team of scientists from Singapore and France has revealed the underlying mechanism for the formation and growth of a fundamental type of tissue - epithelial tubes. Defects in the architecture of epithelial tubes lead to diseases such as cholestasis, atherosclerosis and polycystic kidney disease.

25 Feb 2016

Study reveals role of 'Kurly' protein found in cilia

A new study of a protein found in cilia - the hair-like projections on the cell surface - may help explain how genetic defects in cilia play a role in developmental abnormalities, kidney disease and a number of other disorders.

24 Feb 2016

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

The Mount Desert Island Biological Laboratory has announced that assistant professor Sandra Rieger, Ph.D., has identified two drugs that could potentially be used to reverse peripheral nerve damage, or peripheral neuropathy, resulting from chemotherapy treatment for ovarian, breast, lung, pancreas and other cancers. The drugs also have potential applications for the treatment of peripheral nerve damage caused by diabetes, traumatic injuries and other conditions.

23 Feb 2016

Regulus reports net loss of $7.2 million for fourth quarter 2015

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today reported financial results for the fourth quarter and full-year ended December 31, 2015 and provided a summary of recent corporate highlights.

23 Feb 2016

Masked hypertension linked with increased risks of kidney, heart and vascular damage

Many patients with chronic kidney disease (CKD) have hypertension that is not detected in the clinic, and such 'masked' hypertension is linked with increased risks of kidney, heart, and vascular damage.

22 Feb 2016

NJIT students building low-cost water filter for people suffering from kidney disease in rural Sri Lanka

Backed by a grant from the U.S. Environmental Protection Agency, an interdisciplinary, student-led team from New Jersey Institute of Technology is building a low-cost water filter for villagers in the north central farming region of Sri Lanka who are suffering from high rates of chronic kidney disease.

19 Feb 2016

Patients with chronic kidney disease and periodontitis have higher mortality rate

New findings from the University of Birmingham show that patients with chronic kidney disease patients and periodontitis (severe gum disease) have a higher mortality rate than those with chronic kidney disease alone.

18 Feb 2016

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Quality measures announced today by the Core Quality Measures Collaborative represent a step forward in reducing paperwork and confusion while also allowing providers to focus on measures that impact patient outcomes, the American College of Cardiology (ACC) and the American Heart Association (AHA) said in support of implementation of the proposed cardiovascular measures. But the groups expressed reservations about blood pressure targets included in the measures.

17 Feb 2016

Kidney Disease News and Research

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Study: Conservative care could be a reasonable choice for selected kidney failure patients

Sodium MRI could provide more detailed picture of tissue health and disease

Study could lead to potential new therapeutic target with fewer side effects for hypertension

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

World Kidney Day 2016 focuses on children

Pioneering progress on ADPKD: an interview with Tess Harris

Renal risk factors for NA-treated HBV patients identified

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

Physicians miss opportunities for detection and management of people with prediabetes

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

Scientists reveal underlying mechanism for formation and growth of epithelial tubes

Study reveals role of 'Kurly' protein found in cilia

MDI Biological Laboratory scientist identifies potential drug therapy to reverse peripheral nerve damage

Regulus reports net loss of $7.2 million for fourth quarter 2015

Masked hypertension linked with increased risks of kidney, heart and vascular damage

NJIT students building low-cost water filter for people suffering from kidney disease in rural Sri Lanka

Patients with chronic kidney disease and periodontitis have higher mortality rate

ACC, AHA support implementation of proposed cardiovascular measures, with reservations

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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