Metabolites News and Research

RSS

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

There is an increasing interest in Parkinson's disease (PD) treatment by increasing dopamine content and reducing dopaminergic metabolites in the brain.

17 Jul 2014

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemoprevention is to arrest or reverse the progression of premalignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells.

16 Jul 2014

Scientists develop RNA that binds cGMP

The transmission of signals within cells is dependent on cyclic guanosine monophosphate (cGMP) as an important secondary messenger. German scientists have now developed an RNA that binds cGMP. As reported in the journal Angewandte Chemie, it is possible to suppress the cGMP signal cascade in genetically modified cells that produce this RNA.

10 Jul 2014

Samples from Chobani yogurt contain most virulent form of fungus

Samples isolated from Chobani yogurt that was voluntarily recalled in September 2013 have been found to contain the most virulent form of a fungus called Mucor circinelloides, which is associated with infections in immune-compromised people.

8 Jul 2014

Fungus responsible for outbreak of Greek yogurt can threaten health systems

The fungus responsible for an outbreak of contaminated Greek yogurt last year is not harmless after all but a strain with the ability to cause disease, according to research published in mBio-, the online open-access journal of the American Society for Microbiology.

8 Jul 2014

Use of NMR in diagnostic research: an interview with Elaine Holmes, Imperial College

The Phenome Center developed out of the Olympic drug testing facility, and we've adapted it so that we use NMR spectrometry, which we have three spectrometers, and mass spectrometry, to take blood and urine from hundreds and thousands of people and profile them to get a biochemical fingerprint of every person.

From Bruker BioSpin Group 1 Jul 2014

Cocoa-extract may reduce damage to nerve pathways in Alzheimer's patients' brains

A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer's disease patients' brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer's Disease (JAD).

24 Jun 2014

Single dose restores normal cellular signaling in mouse model of autism

In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old.

18 Jun 2014

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ:CELG), today announced results of additional analyses from the phase III clinical trials of OTEZLA, the Company's oral, selective inhibitor of phosphodiesterase 4 (PDE4).

11 Jun 2014

Injured patients who have alcohol in blood have reduced risk for developing complications

Injured patients who have alcohol in their blood have a reduced risk for developing cardiac and renal complications, according to a study from the University of Illinois at Chicago School of Public Health.

6 Jun 2014

Chinese FDA approves Waters ACQUITY UPLC TQD system as a medical device

Waters Corporation today announced that the Chinese Food and Drug Administration (CFDA) approved the registration of the ACQUITY UPLC TQD system for legal promotion and sale in China as a medical device for routine diagnostic applications and neonatal metabolites diseases screening.

5 Jun 2014

New study provides evidence that bacteria in gut may be linked to children with autism

Children with autism spectrum disorders (ASD) have significantly different concentrations of certain bacterial-produced chemicals, called metabolites, in their feces compared to children without ASD.

20 May 2014

Study reveals surprising relationships between diet and release of hormones that suppress eating

By comparing how gut microbes from human vegetarians and grass-grazing baboons digest different diets, researchers have shown that ancestral human diets, so called "paleo" diets, did not necessarily result in better appetite suppression.

20 May 2014

Specific Technologies unveils SpecID blood culture system at General Meeting of the American Society for Microbiology

Specific Technologies, developer of the SpecID™ system to rapidly detect and identify bacterial species and strain via a metabolomic fingerprint, today announced that for the first time it will showcase its transformative SpecID blood culture system at the 114th General Meeting of the American Society for Microbiology, May 17-20, 2014 in Boston, Massachusetts at the Boston Convention and Exhibition Center.

16 May 2014

People who consume diet rich in resveratrol are likely to develop cardiovascular disease

A study of Italians who consume a diet rich in resveratrol — the compound found in red wine, dark chocolate and berries — finds they live no longer than and are just as likely to develop cardiovascular disease or cancer as those who eat or drink smaller amounts of the antioxidant.

13 May 2014

Metabolites News and Research

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Scientists develop RNA that binds cGMP

Samples from Chobani yogurt contain most virulent form of fungus

Fungus responsible for outbreak of Greek yogurt can threaten health systems

Use of NMR in diagnostic research: an interview with Elaine Holmes, Imperial College

Cocoa-extract may reduce damage to nerve pathways in Alzheimer's patients' brains

Single dose restores normal cellular signaling in mouse model of autism

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

Injured patients who have alcohol in blood have reduced risk for developing complications

Chinese FDA approves Waters ACQUITY UPLC TQD system as a medical device

New study provides evidence that bacteria in gut may be linked to children with autism

Study reveals surprising relationships between diet and release of hormones that suppress eating

Specific Technologies unveils SpecID blood culture system at General Meeting of the American Society for Microbiology

People who consume diet rich in resveratrol are likely to develop cardiovascular disease

Urine test separates nonadherent from treatment-resistant hypertensive patients

Scientists examine Gpr109a receptor to find potential treatment for diabetic retinopathy

Targeting enzyme responsible for glucose metabolism halts tumor growth, say researchers

Metabolon announces launch of fourth-generation metabolomics platform

AB Sciex launches immunosuppressants kit to improve health care

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News