Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Rare mutations in salt handling genes protect against hypertension

Howard Hughes Medical Institute (HHMI) researchers have found that rare mutations in three genes contribute to blood pressure variation in the general population.

7 Apr 2008

Baxter International, Inc. wins patent infringement case

Baxter International, Inc. has won a long-running battle in a patent infringement suit ( Fresenius USA, Inc. et al v. Baxter International Inc. et al. ) against Fresenius Medical Care involving Fresenius ' Number One - selling hemodialysis machine in the United States.

From Baxter International Inc. 7 Apr 2008

Proteolix's Carfilzomib granted orphan drug designation

Proteolix, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to carfilzomib, a selective blocker of proteasome activity for the treatment of multiple myeloma.

3 Apr 2008

Genetic mutations tied to immune comeback during therapy for HIV-1

Researchers with the Infectious Disease Clinical Research Program (IDCRP) at the Uniformed Services University of the Health Sciences (USU) here and the University of Texas Health Science Center at San Antonio have published a patient outcome study in the March 30 online edition of Nature Medicine that may signal a need for a change of thought in the management of HIV.

3 Apr 2008

Potential new treatments for polycystic kidney disease

A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.

3 Apr 2008

Free vascular health checks for the over 40's promises to save 2,000 lives each year

A scheme whereby everyone between the age of 40 to 74 will be given free health screening for vascular diseases is to be introduced in Britain next year.

3 Apr 2008

Angioplasty and stenting for renal artery lesions

The largest-ever randomized study to evaluate the effectiveness of catheter-based interventions in patients with narrowing of the renal artery has shown that angioplasty and stenting offer no benefit over medical therapy.

2 Apr 2008

Gene mutations tied to immune comeback during therapy for HIV-1

A new study by U.S. scientists provides compelling evidence that two genes are linchpins in defining the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy.

31 Mar 2008

University of Kentucky physician revolutionizes gene research

A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes.

28 Mar 2008

Study links chronic illness to coal-mining pollution

Pollution from coal mining may have a negative impact on public health in mining communities, according to data analyzed in a West Virginia University research study.

26 Mar 2008

Uric acid in the blood may be an early sign of diabetic kidney disease

For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

19 Mar 2008

Compound present naturally in grape skin fights the complications of diabetes

Research carried out by scientists at the Peninsula Medical School in the South West of England has found that resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes, according to a paper published in the science journal "Diabetes, Obesity and Metabolism" this week.

19 Mar 2008

Uric acid may provide early clues to diabetic kidney disease

For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease - appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

18 Mar 2008