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New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

UCLA researchers have for the first time identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improved treatments for the deadliest type of skin cancer.

13 Jul 2016

Regular drug use may hamper moral decision making

Regular cocaine and methamphetamine users can have difficulty choosing between right and wrong, perhaps because the specific parts of their brains used for moral processing and evaluating emotions are damaged by their prolonged drug habits.

13 Jul 2016

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure.

13 Jul 2016

Sugar-binding protein galectin-9 could be new weapon to fight HIV

The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped.

13 Jul 2016

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems.

13 Jul 2016

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers have identified a new biological pathway involved in Alzheimer's disease. In experiments using fruit flies, blocking the pathway reduced the death of brain cells, suggesting that interfering with the pathway could represent a promising new strategy to treat the disease in human patients.

13 Jul 2016

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That's why a recent discovery made by Rudy Valentine and a team of researchers holds so much promise.

13 Jul 2016

New ultra-fast approach to modeling protein interactions may pave way for drug development

Protein-protein interactions (PPIs) are the basis of cellular functions, and when these processes are compromised diseases such as cancer emerge. For years scientists have tried with mixed success to map out PPIs to understand cellular processes.

13 Jul 2016

New streamlined approach to genetic testing benefits women with ovarian cancer

A new streamlined approach to genetic testing for women with ovarian cancer provides testing rapidly and affordably, allowing many more patients to benefit from personalised cancer management and their relatives to benefit from cancer prevention strategies.

13 Jul 2016

Scientists discover new biological defense system against pathogenic microorganisms

For the first time in the world, a group of researchers discovered a human immune receptor, which detects the invasion of pathogenic microorganisms.

13 Jul 2016

WHO and partners launch new strategies to reduce violence against children

WHO and partners today launch 7 interlinked strategies to reduce violence against children.

13 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Study shows how increase in BMI contributes to multiple myeloma growth and progression

In a new study published in Cancer Letters, American University researchers show how, as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma, which accounts for about 10 percent of all blood cancers in patients.

12 Jul 2016

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.

12 Jul 2016

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Northwestern Medicine scientists have shown how manipulating a novel target in the brain using gene therapy could lead to new treatments for depression.

12 Jul 2016

Neuroscience studies provide evidence of positive impact of social interaction

Animals prefer contact with other animals rather than drug consumption. – This has been shown by neuroscience studies providing first-time evidence of the positive impact of social interaction and opening up new therapeutic avenues.

12 Jul 2016

Increasing access to MRI scanning: an interview with Jane Kilkenny

MRI scanners use strong magnetic fields, radio waves and field gradients to produce cross sectional images throughout the human body.

12 Jul 2016

Chromatrap reports benefits of ChIP technology in ground breaking research

Chromatrap reports on 3 further customer papers published in different prestigious peer reviewed journals, which cite how its proprietary solid state Chromatin Immunoprecipitation (ChIP) technology has enabled ground breaking research.

From Chromatrap® - Porvair Sciences Ltd 12 Jul 2016

Beagle Freedom Project to award $250,000 in grants to replace animals in experiments

Beagle Freedom Project, a national nonprofit based in Los Angeles, is continuing its mission to further reduce and replace animals in cruel experiences, because it believes that medical research can no longer rely on the use of these animals in controversial experiments.

12 Jul 2016

Drugs News and Research

New treatment approach may benefit relapsed post-transplant blood cancer patients

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

Regular drug use may hamper moral decision making

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

Sugar-binding protein galectin-9 could be new weapon to fight HIV

Changes in cavefish metabolism could lead to new insights into diabetes

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers identify PKD1 protein as potential cause for impaired insulin signaling in diabetics

New ultra-fast approach to modeling protein interactions may pave way for drug development

New streamlined approach to genetic testing benefits women with ovarian cancer

Scientists discover new biological defense system against pathogenic microorganisms

WHO and partners launch new strategies to reduce violence against children

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Study shows how increase in BMI contributes to multiple myeloma growth and progression

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Neuroscience studies provide evidence of positive impact of social interaction

Increasing access to MRI scanning: an interview with Jane Kilkenny

Chromatrap reports benefits of ChIP technology in ground breaking research

Beagle Freedom Project to award $250,000 in grants to replace animals in experiments

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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