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Experts use next-generation genetic sequencing to diagnose suspected brain infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

21 Jun 2016

Shorter course of prostate cancer radiotherapy could save NHS millions of pounds

A shorter course of prostate cancer radiotherapy, involving fewer hospital visits and higher individual doses of radiotherapy, is as effective as the current standard treatment for both survival and quality of life, a major new study reports.

21 Jun 2016

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Mayo Clinic is highlighting the potential merits of using precision medicine in prescribing antidepressants. Details appear in the current issue of Mayo Clinic Proceedings.

21 Jun 2016

Highly efficient bacterial agent could improve treatment of Wilson disease

In the 'Journal of Clinical Investigation', scientists at the Helmholtz Zentrum München describe a small peptide that very efficiently binds excess copper from liver cells. This molecule comes from a bacterium's bag of tricks and could be suitable for treating Wilson disease.

21 Jun 2016

Single, short duration exposure of general anesthesia appears to cause no cognitive harm in healthy, young children

A recent study concluded that very young, healthy children undergoing short surgical procedures requiring a single exposure to general anesthesia did not exhibit any effect on the cognitive outcomes tested, according to SmartTots, a public-private partnership of the International Anesthesia Research Society and the U.S. Food and Drug Administration.

21 Jun 2016

Telephone counseling can help make cancer genetic services more accessible to rural women

Ever since Angelina Jolie used cancer genetic counseling and testing to learn about her risk for hereditary breast and ovarian cancer, many other women have chosen to do the same.

21 Jun 2016

Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

Up to 30 percent of people who receive organ transplants will develop diabetes, but researchers are unsure why. Although doctors typically blame immunosuppressive drugs that transplant recipients take to prevent organ rejection, it's unclear why some people develop the lifelong disorder, while others do not.

21 Jun 2016

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer.

21 Jun 2016

Researchers identify 38 independent genomic regions linked to migraine

The results of the largest genetic study on migraine thus far were published online in the journal Nature Genetics today, June 20. The study was based on DNA samples of 375,000 European, American and Australian participants. Almost 60,000 of them suffer from migraine.

21 Jun 2016

Cytoreductive nephrectomy can extend survival of metastatic kidney cancer patients

Surgery to remove a cancerous kidney can often lengthen the lives of patients receiving targeted therapy for metastatic kidney cancer, but only about three in ten such patients undergo the procedure, according to a new study by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital.

21 Jun 2016

New study sheds light on sexual health of gay and bisexual men

More gay and bisexual men than ever are getting tested for HIV, according to new data from the National Gay Men's Sex Survey. The survey is the largest of its kind in the UK and sheds light on the sexual health of men who have sex with men.

21 Jun 2016

Researchers aim to improve medical treatment for people with insect venom allergy

A team of researchers has elucidated individual profiles of allergy reactivity in patients that are not protected after treatment with immunotherapy. The aim is to improve medical treatment of people who are allergic to insect stings.

21 Jun 2016

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Researchers at University of California San Diego School of Medicine and University of California, San Francisco School of Medicine report that more than 1 in 3 atrial fibrillation (AF) patients at intermediate to high risk for stroke are treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners.

21 Jun 2016

Apixaban effective in polypharmacy setting

The superiority of apixaban over warfarin in patients with atrial fibrillation is maintained in those taking multiple medications, shows further analysis of the ARISTOTLE trial.

21 Jun 2016

Rice University researchers synthesize new anti-cancer agent

Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand.

20 Jun 2016

New method helps analyse how cold viruses penetrate into cells

Cold viruses cause us irritation by penetrating into our cells and transporting their RNA into the cytoplasma of the infected cells. This is the only way they can multiply. The details of how the transfer of the RNA from within the virus occurs are difficult to study.

20 Jun 2016

New blood test could help predict severity of pulmonary arterial hypertension

Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs.

20 Jun 2016

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Firstly, a sample must be transported from the clinic to the laboratory. Simple tests may be undertaken in a small lab within the hospital or clinic, whilst complex testing such as drug susceptibility testing is often done in a large centralized laboratory many miles from the clinic

20 Jun 2016

Study emphasizes need for Ryan White HIV/AIDS Program to receive basic HIV care

A Johns Hopkins University School of Medicine study of insurance coverage of more than 28,000 people with HIV concludes that a decades-old program that offers free medical care remains a critical necessity despite the availability of coverage under the Affordable Care Act (ACA).

20 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Drugs News and Research

Experts use next-generation genetic sequencing to diagnose suspected brain infections

Shorter course of prostate cancer radiotherapy could save NHS millions of pounds

Mayo Clinic highlights potential merits of individualizing treatment for patients taking antidepressants

Highly efficient bacterial agent could improve treatment of Wilson disease

Single, short duration exposure of general anesthesia appears to cause no cognitive harm in healthy, young children

Telephone counseling can help make cancer genetic services more accessible to rural women

Kidney transplant recipients with inflammation prior to surgery more likely to develop diabetes

Potential therapeutic approaches to combat chronic myeloid leukemia

Researchers identify 38 independent genomic regions linked to migraine

Cytoreductive nephrectomy can extend survival of metastatic kidney cancer patients

New study sheds light on sexual health of gay and bisexual men

Researchers aim to improve medical treatment for people with insect venom allergy

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Apixaban effective in polypharmacy setting

Rice University researchers synthesize new anti-cancer agent

New method helps analyse how cold viruses penetrate into cells

New blood test could help predict severity of pulmonary arterial hypertension

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Study emphasizes need for Ryan White HIV/AIDS Program to receive basic HIV care

TUM researchers uncover molecular mechanism of thalidomide

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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