Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Vaccinating mothers during pregnancy may be an effective strategy to boost COVID antibodies in infants

Women with COVID in pregnancy who are subsequently vaccinated after recovery, but prior to delivery, are more likely to pass antibodies on to the child than similarly infected but unvaccinated mothers are.

27 Sep 2022

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

Researchers investigated the differences in vaccination- and previous infection-induced immunities against the Omicron BA.2 and BA.4/5 subvariants of SARS-CoV-2.

27 Sep 2022

The antibody response against SARS-CoV-2 in patients pre- and post-infusion with commercial intravenous immunoglobulin products

Researchers comparatively evaluated antibody responses against SARS-CoV-2 among immunodeficient individuals pre- and post-intravenous immunoglobulin product infusions.

27 Sep 2022

First data on Pfizer-BioNTech's Omicron BA.4/5 combination vaccine

In a recent study posted to the bioRxiv* preprint server, researchers from Germany and the United States analyzed the association between exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 spike glycoprotein and pan-Omicron neutralization.

27 Sep 2022

Review says dose of approved COVID-19 vaccines based on weak evidence

A recent study posted to the medRxiv* preprint server reviewed early-phase dose-finding trials to examine the study design, safety, and early antibody response data on approved coronavirus disease 2019 (COVID-19) vaccines and gain insights on design improvements for future candidate COVID-19 vaccine clinical trials.

26 Sep 2022

Study looks at boosting with variant-derived COVID vaccine

In a recent study posted to bioRxiv*, researchers at Washington University School of Medicine, St. Louis, demonstrated that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine booster elicits robust germinal center (GC) B cell responses.

26 Sep 2022

Study characterizes immunological signature of SARS-CoV-2 infection in children

A recent study has demonstrated that the clinical severity of COVID-19 in children depends on the dynamics of immune response induced by SARS-CoV-2 infection.

26 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Why do some people become seriously ill with Covid-19, while others have no symptoms at all? The answer may lie in the proteins our immune system has previously been exposed to.

23 Sep 2022

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

22 Sep 2022

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Vaccine boosters and breakthrough infections following vaccination both provide a substantial and potentially pandemic-breaking immunity against COVID-19, according to new laboratory research from Oregon Health & Science University.

22 Sep 2022

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Is SARS-CoV-2 hiding in your fat cells? A study by Stanford Medicine investigators shows that SARS-CoV-2 can infect human fat tissue.

22 Sep 2022

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

In a new study, researchers designed a liquid biomarker panel consisting of macrophage and monocyte-related soluble factors and circulating spike proteins to understand profiles of immune dysregulation in patients with post-acute sequelae of COVID-19.

22 Sep 2022

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Researchers investigated the SARS-CoV-2 VOC Omicron's immune escape mechanisms.

22 Sep 2022

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

Antibody News and Research

Further Reading

Vaccinating mothers during pregnancy may be an effective strategy to boost COVID antibodies in infants

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

The antibody response against SARS-CoV-2 in patients pre- and post-infusion with commercial intravenous immunoglobulin products

First data on Pfizer-BioNTech's Omicron BA.4/5 combination vaccine

Review says dose of approved COVID-19 vaccines based on weak evidence

Study looks at boosting with variant-derived COVID vaccine

Study characterizes immunological signature of SARS-CoV-2 infection in children

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

Common germline variants of APOE contribute to differential COVID-19 outcomes

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Study paves the way for new therapies, vaccines that lead to stronger immunity against Covid-19

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Vaccine boosters and breakthrough infections provide substantial immunity against COVID-19

Stanford Medicine study shows SARS-CoV-2 can infect human fat tissue

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

Does BA.2 breakthrough infection shift cross-neutralization activity towards the BA.4 and BA.5 Omicron sublineages?

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

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