Antigen News and Research

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In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

A new study aimed to analyze SARS-CoV-2 specific T-cells in unexposed individuals.

2 Dec 2021

Men with inherited gene mutation have high risk of aggressive prostate cancer

Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found.

2 Dec 2021

NEI researchers identify unique population of B cells that tamps down the immune system

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation.

2 Dec 2021

Systematic survey of human SARS-CoV-2 monoclonal antibodies

Scientists have mined information from several research publications and patents to create a dataset of approximately 8000 human antibodies to the SARS-CoV-2 spike from more than 200 donors.

2 Dec 2021

Preventing SARS-CoV-2 transmission at large indoor events

A new trial showed that indoor live events are not associated with an increased risk of SARS-CoV-2 infection, provided preventive interventions are in place.

2 Dec 2021

Novel set of immune cells may have the opposite effect in multiple sclerosis, other brain conditions

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Comparison of peptides from human cardiac proteins and SARS-CoV-2 proteins

A new study investigated whether linear peptides contained in proteins (primarily expressed in the heart) also occur in the SARS-CoV-2 proteome.

1 Dec 2021

Study compares NAbs from natural SARS-CoV-2 infection vs. vaccine induced against symptomatic infection

Scientists have recently compared the levels of antibody concentrations in unvaccinated, SARS-CoV-2 convalescent individuals and COVID-19 specific antibodies in vaccinated individuals.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Study shows that nucleic acid amplification tests more accurate in detecting SARS-CoV-2 than rapid antigen

Researchers use reference preparations from pooled swab samples to compare the analytical sensitivity of different SARS-CoV-2 assays

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021