Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Inherited gene after black plague may help treat HIV patients co-infected with hepatitis C

The Black Death swept Europe in the 14th century eliminating up to half of the population but it left genetic clues that now may aid a University of Cincinnati researcher in treating HIV patients co-infected with hepatitis C using an anti-retroviral drug therapy.

7 Mar 2016

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

A protein modified to increase the amount of time it circulates in the bloodstream appears to reverse liver fibrosis and cirrhosis in rats, according to results of a study led by Johns Hopkins researchers.

3 Mar 2016

New international survey provides insights into emotional truths of living with IPF

An international survey of over 500 people living with idiopathic pulmonary fibrosis (IPF) in more than 20 countries worldwide reveals the real-life emotions faced by those with the devastating disease.

1 Mar 2016

Rare Disease Day 2016: Boehringer Ingelheim launches new initiatives to raise awareness of IPF

Boehringer Ingelheim, working with pharmaphorum media, has brought together patients, patient groups and globally renowned clinicians to launch a report into IPF entitled Inspiration - a new initiative dedicated to raising awareness of IPF,1 a rare disease that is relatively unheard of, frequently misdiagnosed and little understood.

1 Mar 2016

Over-expression of heme oxygenase-1 enzyme protects the heart from doxorubicin damage

Life-threatening heart damage is an adverse side effect of the cancer drug doxorubicin, damage that also limits the use of newer chemotherapeutic agents such as trastuzumab and imatinib. The ability to protect the heart from these side effects would benefit patients, including cancer survivors who are at risk of developing heart damage years later, and it also could allow safer use of these drugs at higher doses.

26 Feb 2016

High-salt diet may contribute to liver damage

A sprinkle of salt can bring out the flavor of just about any dish. However, it's well known that too much can lead to high blood pressure, a potentially dangerous condition if left untreated.

24 Feb 2016

New computer program and electronic stethoscope developed to diagnose lung problems

The classic stethoscope has entered the digital age. Medical researchers have created a computer program that connects to an electronic stethoscope to classify lung sounds into five common diagnostic categories.

24 Feb 2016

UAB researchers use Malvern’s NanoSight NS300 system to figure out role of exosomes in disease transmission

Data measured using the NanoSight NS300 from Malvern Instruments is providing new insights into the role of exosomes in diseases such as cancer, arthritis, Alzheimer’s disease and cystic fibrosis, in pioneering research at the University of Alabama - Birmingham (UAB).

23 Feb 2016

UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

Heidi M. Mansour, PhD, assistant professor in the University of Arizona College of Pharmacy, is working to develop advanced dry powder inhalers to treat and prevent pulmonary diseases.

23 Feb 2016

Regulus reports net loss of $7.2 million for fourth quarter 2015

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today reported financial results for the fourth quarter and full-year ended December 31, 2015 and provided a summary of recent corporate highlights.

23 Feb 2016

Researchers take major step towards developing a cystic fibrosis drug

Researchers from Eindhoven University of Technology and McGill University in Montreal (Canada) have taken an important step towards developing a drug against cystic fibrosis.

18 Feb 2016

Apellis Pharmaceuticals completes $47.1M Series D preferred stock financing

Apellis Pharmaceuticals, Inc., today announced that it has completed a $47.1 million Series D preferred stock financing, co-led by new investors Cormorant Asset Management, Hillhouse Capital Group and venBio Global Strategic Fund, joining existing investors Morningside Venture Investments, AJU IB Investment, and Epidarex Capital.

12 Feb 2016

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle.

11 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science.

8 Feb 2016

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes.

7 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

29 Jan 2016

Insights into exosomes role in disease transmission gained using NanoSight from Malvern

Data measured using the NanoSight NS300 from Malvern Panalytical is providing new insights into the role of exosomes in diseases such as cancer, arthritis, Alzheimer’s disease and cystic fibrosis, in pioneering research at the University of Alabama - Birmingham (UAB).

From Malvern Panalytical 28 Jan 2016

Fibrosis News and Research

Further Reading

Inherited gene after black plague may help treat HIV patients co-infected with hepatitis C

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

New international survey provides insights into emotional truths of living with IPF

Rare Disease Day 2016: Boehringer Ingelheim launches new initiatives to raise awareness of IPF

Over-expression of heme oxygenase-1 enzyme protects the heart from doxorubicin damage

High-salt diet may contribute to liver damage

New computer program and electronic stethoscope developed to diagnose lung problems

UAB researchers use Malvern’s NanoSight NS300 system to figure out role of exosomes in disease transmission

UA College of Pharmacy assistant professor developing dry powder inhalers to treat pulmonary diseases

Regulus reports net loss of $7.2 million for fourth quarter 2015

Researchers take major step towards developing a cystic fibrosis drug

Apellis Pharmaceuticals completes $47.1M Series D preferred stock financing

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

UC San Diego School of Medicine launches new NAFLD Research Center

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Three Case Western faculty members receive funding to develop new diagnostic technologies

Insights into exosomes role in disease transmission gained using NanoSight from Malvern

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News