Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Specific protein can be used as a brain marker to indicate whether emotional memories can be changed

Researchers have discovered that a particular protein can be used as a brain marker to indicate whether emotional memories can be changed or forgotten.

3 Oct 2021

Early accumulation of tau proteins in the brain more effective at predicting memory impairment

Researchers at Karolinska Institutet in Sweden have compared how well different Alzheimer's biomarkers predict the progression of the disease and its effect on memory.

1 Oct 2021

Scientists find new possibilities for treatment of lung cancers in 'never smokers'

Despite smoking's well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called "never-smokers," a study led by scientists at Washington University School of Medicine in St. Louis demonstrates new possibilities for treating these baffling tumors.

1 Oct 2021

Research points the way to identifying new precision treatments for cancer

Researchers at University of California San Diego and University of California San Francisco have mapped out how hundreds of mutations involved in two types of cancer affect the activity of discrete groups of proteins that are the ultimate actors behind the disease.

30 Sep 2021

Scientists offers new hope for future treatment of sepsis

Sepsis, the body's life-threatening response to infection affecting about 1.7 million adults in the United States each year, can lead to multisystem organ failure with a high mortality rate.

29 Sep 2021

Alzheimer’s drug targets people with mild cognitive impairment. What does that mean?

The approval of a controversial new drug for Alzheimer's disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging.

29 Sep 2021

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

The University of Texas MD Anderson Cancer Center and BostonGene Corporation today announced a strategic alliance to advance the development and clinical integration of multiplatform biomarker signatures.

28 Sep 2021

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Kristina Simonyan, MD, PhD, Dr med, director of laryngology research at Mass Eye and Ear, has been awarded an $11.9 million P50 Clinical Research Center Grant from the National Institute on Deafness and Other Communicable Disorders of the National Institute of Health to form a new multidisciplinary center across four academic medical institutions that will be committed to conducting research on laryngeal dystonia and voice tremor, two debilitating neurological voice disorders.

28 Sep 2021

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with SARS-CoV-2 infection.

28 Sep 2021

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

National task force advocates removal of race from the kidney function algorithm

A national task force announced Thursday that it is recommending the immediate implementation of a new diagnostic equation for measuring kidney function, which advocates say will promote health equity and increase access to transplantation for Black patients.

24 Sep 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

Researchers identify two subtypes of metastatic prostate cancer

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease.

24 Sep 2021

Salk professor selected as HHMI investigator

Salk Professor Kay Tye has been selected as a Howard Hughes Medical Institute (HHMI) investigator, joining a prestigious group of more than 250 HHMI investigators across the United States who are tackling important scientific questions.

23 Sep 2021

Adhesive protein facilitates cluster formation in circulating tumor cells

Circulating tumor cells (CTCs) with stem cell features use the adhesive protein ICAM1 to facilitate formation of CTC clusters, which can travel from primary tumors to other organs in the body, according to a Northwestern Medicine study published in Nature Communications.

22 Sep 2021

New study links history of migraines and hot flashes as well as an increased risk of heart disease

Migraines affect more women than men. Hormones appear to be a key reason why. Fluctuating hormone levels can also cause hot flashes.

22 Sep 2021

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Penn Medicine and The Wistar Institute have been awarded a prestigious $11.7 million Specialized Programs of Research Excellence, or SPORE, grant from the National Cancer Institute.

22 Sep 2021

Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Cancer causing high-risk human papillomaviruses (HR-HPV) are responsible for the rising incidence of HR-HPV–driven head and neck cancers (HNC), particularly oropharyngeal cancers (OPC, or throat cancers). Investigators have determined that HR-HPV DNA can be detected in saliva in most patients with HPV-driven OPC at the time of diagnosis. This work highlights a potentially life-saving screening program based on salivary HR-HPV DNA testing for early cancer detection and patient monitoring. Their findings appear in The Journal of Molecular Diagnostics, published by Elsevier.

22 Sep 2021

Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Beckman Coulter announced the results of a prospective study carried out across two European hospitals, which found that Monocyte Distribution Width, in combination with White Blood Cell Count with Differential, has the diagnostic accuracy to detect the risk of sepsis and severe infection upon patient presentation in A&E, particularly when assessed in patients with a lower likelihood of sepsis.

22 Sep 2021

Biomarker News and Research

Further Reading

Specific protein can be used as a brain marker to indicate whether emotional memories can be changed

Early accumulation of tau proteins in the brain more effective at predicting memory impairment

Scientists find new possibilities for treatment of lung cancers in 'never smokers'

Research points the way to identifying new precision treatments for cancer

Scientists offers new hope for future treatment of sepsis

Alzheimer’s drug targets people with mild cognitive impairment. What does that mean?

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

National task force advocates removal of race from the kidney function algorithm

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Researchers identify two subtypes of metastatic prostate cancer

Salk professor selected as HHMI investigator

Adhesive protein facilitates cluster formation in circulating tumor cells

New study links history of migraines and hot flashes as well as an increased risk of heart disease

Penn Medicine and Wistar secure $11.7 million SPORE grant for three melanoma research projects

Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Researchers seek to identify the role of hypoxia on red blood cell aging

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

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