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Researchers find way to make pediatric brain cancers respond better to therapies

Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.

28 Aug 2020

SARS discovery boots search for COVID-19 drugs

An extensive search and testing of current drugs and drug-like compounds has revealed compounds previously developed to fight SARS might also work against COVID-19.

27 Aug 2020

New approach to combination drug design could be applied to disease therapies beyond diabetes

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered.

27 Aug 2020

Study offers hope for treatment of Krabbe disease

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the condition die before they turn 2.

26 Aug 2020

Inhaled steroid ciclesonide suppresses SARS-CoV-2 replication in vitro

A new paper by researchers at Japan’s National Institute of Infectious Diseases and published on the preprint server bioRxiv in August 2020 reports the in vitro suppression of coronavirus (CoV) replication by an inhaled corticosteroid (ICS) ciclesonide.

26 Aug 2020

Artificial intelligence method can rapidly and remotely detect fentanyl and derivatives

To help keep first responders safe, University of Central Florida researchers have developed an artificial intelligence method that not only rapidly and remotely detects the powerful drug fentanyl, but also teaches itself to detect any previously unknown derivatives made in clandestine batches.

25 Aug 2020

Researchers identify potential drug target for curtailing cancer metastasis

Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis.

24 Aug 2020

RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

Study identifies livestock husbandry practices associated with increased risk of infection

The risk of transmitting the livestock virus PPRV, which threatens 80 percent of the world's sheep and goats, increases with certain husbandry practices but not herd size.

24 Aug 2020

Research suggests seaweed extract and xylitol may help protect against COVID-19

Researchers in the United States have demonstrated the antiviral effect of three candidate nasal spray formulations against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

24 Aug 2020

Accidental discovery of new antibiotic proven effective after several experiments

It all happened by chance. It was a hot summer day nine years ago. Inside the laboratory, the team was working on cancer research. On the lab bench, various medications were being tested on cancer cells.

24 Aug 2020

Study reveals a promising method for treating multiple sclerosis

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in degenerative diseases.

24 Aug 2020

Developing more precise, targeted therapy for a highly aggressive breast cancer

Taking advantage of a cancer cell's altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.

21 Aug 2020

CARE consortium launches to accelerate drug discovery and development for COVID-19

CARE a new consortium supported by the Innovative Medicines Initiative public-private partnership announced its launch today to accelerate the discovery and development of urgently needed medicines to treat SARS-CoV-2, the virus that causes COVID-19.

19 Aug 2020

Researchers identify new therapeutic target for Alzheimer's disease

Scientists at St. Jude Children's Research Hospital are advancing understanding of a potential Alzheimer's disease treatment.

18 Aug 2020

Cashew shell compound may help repair damaged nerves

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

17 Aug 2020

New treatment approach strengthens motor function and muscle of aged mice

In an aging society, one of the most important and urgent tasks of scientific research is to counteract the decline in motor function and muscle weakness that accompanies the aging process.

17 Aug 2020

Preexisting drug shows promise as a weapon against SARS-CoV-2 virus

First appearing in late 2019 in Wuhan City, China, the SARS-CoV-2 virus continues to cause sickness and death across the globe.

14 Aug 2020

Chemists create complex, oxygen-containing molecules that are normally made by plants

Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.

14 Aug 2020

Study: Lipoic acid supplements promote weight loss in certain obese adults

A compound given as a dietary supplement to overweight but otherwise healthy people in a clinical trial caused many of the patients to slim down, research by Oregon State University and Oregon Health & Science University showed.

12 Aug 2020