Immune System News and Research

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Study finds association between pesticide exposure and stillbirth risk

Living less than about one-third of a mile from pesticide use prior to conception and during early pregnancy could increase the risk of stillbirths, according to new research led by researchers at the Mel and Enid Zuckerman College of Public Health and Southwest Environmental Health Sciences Center.

7 Aug 2024

Nasal microbiome composition influences how well multi-resistant bugs can thrive in the nose

Whether dangerous staphylococci survive in the nose depends on what other bacteria are present - and how they obtain iron.

7 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

7 Aug 2024

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

Immunobiologists Robert Schreiber, PhD, (left) and Hussein Sultan, PhD, of Washington University School of Medicine in St. Louis, found that a subset of immune cells that normally puts the brakes on the immune system to prevent it from attacking the body's healthy cells inadvertently also dampens cancer immunotherapy.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Researchers uncover immune system barrier to cancer treatment

By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.

7 Aug 2024

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

The complex dynamics between liver cancer stem cells (CSCs) and immune cells within the tumor microenvironment (TME) are central to the progression of liver cancer. These interactions are critical in creating an immunosuppressive setting that significantly impacts the response to immunotherapy. Liver CSCs, responsible for tumor initiation, metastasis, therapeutic resistance, and recurrence, exhibit heterogeneity and are characterized by various surface markers that contribute to their stemness and metastatic potential.

7 Aug 2024

Innovative nasal spray and vaccine for respiratory virus protection

A team of researchers, led by the University of Houston, has discovered two new ways of preventing and treating respiratory viruses.

6 Aug 2024

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.

6 Aug 2024

New target identified for melanoma resistant to current therapies

Some proteins, such as programmed cell death protein 1 (PD1), can stop the immune system from attacking cancer cells and, therefore, support the growth of cancer.

6 Aug 2024

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target malignant cells while sparing normal tissues.

6 Aug 2024

Upper respiratory microbiome shows age, sex, and lifestyle impacts, study finds

A Dutch study analyzed the upper respiratory tract microbiome across various age groups, finding significant associations between microbial composition, age, sex, and lifestyle factors like smoking and antibiotic use.

5 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

5 Aug 2024

Immune System News and Research

Study finds association between pesticide exposure and stillbirth risk

Nasal microbiome composition influences how well multi-resistant bugs can thrive in the nose

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

KAUST researchers uncover LINE-1 RNA’s role in triggering bone repair

Discovery of Tr1 cells as a barrier to cancer immunotherapy offers new hope for treatment

METRNL protein identified as key player in cancer progression

Researchers uncover immune system barrier to cancer treatment

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

Innovative nasal spray and vaccine for respiratory virus protection

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

New target identified for melanoma resistant to current therapies

Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes

Upper respiratory microbiome shows age, sex, and lifestyle impacts, study finds

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

Natural compound from skin bacteria shows promise as tyrosinase inhibitor for skincare

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Pioneering study brings leishmaniasis vaccine development closer

Mast cells found to capture and employ neutrophils during allergic reactions

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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