Mass Spectrometry News and Research

RSS

Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

FDA purchases Waters ACQUITY UPLC Systems for protecting the U.S. food supply

Waters Corporation announced today that the U.S. Food and Drug Administration's Center for Food Safety and Applied Nutrition (CFSAN), College Park, MD recently purchased nine Waters® ACQUITY UltraPerformance LC® (UPLC®) Systems to support its priority to protect the U.S. food supply by monitoring domestically-produced and imported food sold in interstate commerce.

21 Oct 2009

Researchers develop new technique to study the mechanisms behind diseases in more detail

Researchers have previously been able to analyse which sugar structures are to be found on certain proteins, but not exactly where on the protein they are positioned. This is now possible thanks to a new technique developed at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

20 Oct 2009

PharmaNet Development to display innovative solutions at 2009 AAPS Annual Meeting and Exposition

PharmaNet Development Group, Inc., a leading provider of clinical development services to innovative pharmaceutical, biotechnology, generic drug and medical device companies, today announced that the Company and its subsidiaries Anapharm and Taylor Technology will be showcasing a range of innovative solutions at the 2009 AAPS Annual Meeting and Exposition.

13 Oct 2009

Wake Forest University School of Medicine honours researchers

Wake Forest University School of Medicine honored eight of its researchers with awards for excellence at the 13th Annual Research Awards Day Oct. 1.

12 Oct 2009

Dominion Diagnostics enhances laboratory testing procedure for chronic opioid pharmacotherapy

Only a short time after introducing its newly developed and validated tapentadol assay, Dominion Diagnostics (Dominion) is pleased to announce an important enhancement to another clinical laboratory test.

8 Oct 2009

New study to assess the risk of heart disease in diabetics

In a new international partnership, Dr. Randy Nelson, a researcher at Arizona State University's Biodesign Institute, and Dr. Tai E-Shyong , associate professor at Singapore's National University Hospital, National University Health System (NUHS), have teamed up to assess the risk of heart disease in diabetics with greater accuracy.

8 Oct 2009

PNNL scientist Dick Smith awarded Human Proteome Organization's Discovery Award

Laboratory and Battelle Fellow Dick Smith of the Department of Energy's Pacific Northwest National Laboratory has been recognized for his many accomplishments in pioneering the development of proteomics tools. Scientists use these instruments to study the array of proteins and related molecules that make up much of human blood and tissues.

3 Oct 2009

Increase in omega-3 fatty acid levels can prevent strokes, according to research

Research led by Hernan A. Bazan, MD, Assistant Professor of Surgery, Section of Vascular Surgery, at LSU Health Sciences Center New Orleans School of Medicine, has found that unstable carotid artery plaques - those in danger of rupturing and leading to a stroke - contain more inflammation and significantly less omega-3 fatty acids than asymptomatic plaques.

3 Oct 2009

Epigentek Group releases SuperSense Methylated DNA Quantification kit

Epigentek Group Inc. today announced that it released the SuperSense(TM) Methylated DNA Quantification Kit to complete its line of methylated DNA quantification products. The SuperSense(TM) kit fluorometrically measures global DNA methylation shifts.

1 Oct 2009

Coupling electrosurgery with mass spectrometry for real-time identification of tumor tissues

Instead of the classic scalpel, surgeons can also operate with an electroscalpel. A significant advantage to this technique is that while a cut is being made, blood vessels are closed off and hemorrhaging eliminated. Now another advantage may be added as well: a German-Hungarian research team has developed a mass-spectrometry-based technique by which tissues can be analyzed during a surgical procedure.

30 Sep 2009

Lab-on-a-chip performs 1,000 chemical reactions at once

Flasks, beakers, and hot plates may soon be a thing of the past in medicinal chemistry labs. Instead of handling a few experiments on a benchtop, scientists may simply pop a microchip into a computer and instantly run thousands of chemical reactions, with results literally shrinking the lab down to the size of a thumbnail.

From Siemens Healthineers 23 Sep 2009

Bioscreen Instruments to be Labcyte's partner in India

Labcyte, the developer of acoustic liquid transfer, with systems in all top 10 pharmaceutical companies, today announced the selection of Bioscreen Instruments Pvt. Ltd. as its exclusive distributor in India.

23 Sep 2009

Novel cleavage sites for enzyme caspase-3 identified

Investigators at Burnham Institute for Medical Research (Burnham) have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called N-terminomics, Guy Salvesen, Ph.D., professor and director of the Apoptosis and Cell Death Research program of Burnham's NCI-designated Cancer Center, and colleagues determined the cleavage sites on target proteins and found, contrary to previous understanding, that caspase-3 targets α-helices as well as unstructured loops.

22 Sep 2009

Three German laboratories utilize Bruker’s molecular identification solution

At the 61st Annual Meeting of the German Society for Hygiene and Microbiology on September 20-23, 2009 in Goettingen, Bruker Daltonics announces that three major German private clinical microbiology laboratories have extended their accreditation according to DIN EN ISO 15189 to include the use of Bruker’s MALDI Biotyper molecular identification solution.

21 Sep 2009

Research program to study personalized medicine

A new collaborative research program that will use the power of metabolomic profiling to help advance the concept of personalized medicine was announced September 17, 2009 by the Burnham Institute for Medical Research and the Sarah W. Stedman Nutrition and Metabolism Center at Duke University Medical Center.

18 Sep 2009

New tool developed to provide precise and cost-effective data collection for drug discovery efforts

Cancer and cell biology experts at the University of Cincinnati (UC) have developed a new mass spectrometry-based tool they say provides more precise, cost-effective data collection for drug discovery efforts.

18 Sep 2009

Dominion develops and validates clinical quantitative assays for tapentadol

Dominion Diagnostics (Dominion) has recently developed and validated one of the first clinical quantitative assays for the drug tapentadol (Nucynta(TM)) performed by liquid chromatography/tandem mass spectrometry (LC/MS/MS). Tapentadol, recently approved for use by the FDA, is a centrally-active analgesic that has demonstrated efficacy in pain relief with improved gastrointestinal tolerability compared to other opioids for pain management.

15 Sep 2009

Elderberry extract prevents H1N1 infection in vitro

A recent research study has given new scientific evidence to the long-held empirical belief that elderberries possess antiviral activities. The research involved a specific, reproducible elderberry extract developed by HerbalScience Group LLC, and succeeded in identifying key chemical components of the extract that inhibited in vitro infection and were shown to bind directly to Human Influenza A (H1N1) virus particles. The binding blocked the ability of the viruses to enter host cells, and thereby effectively preventing H1N1 infection in vitro.

11 Sep 2009

Thermo Fisher Scientific receives Ringier Technology Innovation Award

Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, today announced that it has received a Ringier Technology Innovation Award for its role in helping Chinese laboratories quickly develop melamine detection capabilities following the discovery of melamine-tainted milk and infant formula in China. The award was presented by Ringier Trade Publishing, which publishes China's leading food industry magazine, Food Manufacturing Journal.

From Thermo Fisher Scientific Inc. 9 Sep 2009

Optimized turmeric extracts may prevent memory loss

scientists with HerbalScience Group LLC, working with researchers from other organizations and medical institutions, conducted an in-depth study of optimized turmeric extracts, demonstrating that key bioactives in the botanical extracts inhibit aggregation and release of amyloid, a protein fragment considered a prime causal suspect in Alzheimer's disease.

3 Sep 2009