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PKCζ protein plays a critical role in regulating tumor metabolism

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar called glucose. Unfortunately, this treatment approach not only fails to work, it backfires-glucose-starved tumors actually get more aggressive.

2 Feb 2013

Alleviation of global hunger an urgent agenda for world leaders in 2013

"The fact that an inexpensive and readily treatable condition that affects 868 million people, kills 2.3 million children per year, and was targeted as a Millennium Development Goal, should remain uncontrolled year after year is as shocking as it is shameful," a Lancet editorial writes about global hunger.

2 Feb 2013

Modafinil may help some people to reduce drinking by improving their impulse control

Poor impulse control contributes to one's inability to control the consumption of rewarding substances, like food, alcohol, and other drugs. This can lead to the development of addiction. FDA-approved medications for alcoholism, like naltrexone (Revia) and disulfiram (Antabuse), are thought to reduce alcohol consumption by curbing cravings and creating unpleasant reactions to alcohol, effects which reduce the desire to drink alcohol.

2 Feb 2013

Research roundup: Concerns about ambulance diversions; The health law's impact on nursing homes; Mental health parity

Hospitals across the United States routinely turn away ambulances to relieve overcrowding, but the practice remains controversial. Researchers in this study aimed to identify the impact of Massachusetts' 2009 ambulance diversion ban.

2 Feb 2013

FDA announces federal judge approval of Ben Venue consent decree

The U.S. Food and Drug Administration announced today that a federal judge has approved a consent decree of permanent injunction against Ben Venue Laboratories, Inc., and three of its corporate officers for failing to comply with current good manufacturing practice requirements as required by federal law.

2 Feb 2013

Dairy intake may increase risk of bone mineral density in the hip

A study by researchers at the Institute for Aging Research (IFAR) at Hebrew SeniorLife, an affiliate of Harvard Medical School (HMS), has found that dairy intake -specifically milk and yogurt -is associated with higher bone mineral density (BMD) in the hip, but not the spine.

1 Feb 2013

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

The U.S. Food and Drug Administration today approved Ravicti (glycerol phenylbutyrate) for the chronic management of some urea cycle disorders (UCDs) in patients ages 2 years and older.

1 Feb 2013

New CT system reduces radiation exposure in patients undergoing CCTA

Researchers using a newly approved advanced computed tomography (CT) system were able to significantly reduce radiation exposure in patients undergoing coronary CT angiography (CCTA), according to a new study published online in the journal Radiology.

1 Feb 2013

Possible link between outdoor food ads and a tendency to pack on pounds

Past studies have suggested a relationship between neighborhood characteristics and obesity, as well as a connection between obesity and advertisements on television and in magazines.

1 Feb 2013

Gates Foundation, German government, private sector to pool $108M to reduce malnutrition globally

"The German Federal Ministry for Economic Cooperation and Development, or BMZ, and the Bill & Melinda Gates Foundation, together with German and European businesses, are pooling investments worth €80 million ($108 million) to reduce malnutrition around the world," Devex reports.

1 Feb 2013

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Merck, known as MSD outside the United States and Canada, today announced financial results for the fourth quarter and full year of 2012.

1 Feb 2013

Galectin submits GR-MD-02 IND application with FDA for treatment of liver fibrosis

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, announced today that it submitted an Investigational New Drug (IND) application to the US Food and Drug Administration (FDA) on January 30, 2013.

1 Feb 2013

Mental health in young people: an interview with Professor Colum Dunne

Ireland, and many other countries, is witnessing increases in problematic and complex youth mental health challenges. In Ireland, specifically, there has been a rash of high profile cases where young people have unfortunately not been able to deal with stress, bullying and other issues.

1 Feb 2013

ArQule, Daiichi Sankyo initiate enrollment in tivantinib Phase 3 trial for hepatocellular carcinoma

Daiichi Sankyo Company, Limited and ArQule, Inc. today announced that the first patient has been enrolled in the pivotal Phase 3 METIV-HCC (MET-high patients with tivantinib in HCC) trial of tivantinib (ARQ 197).

31 Jan 2013

Celsion's ThermoDox does not meet primary endpoint in Phase III HCC study

Celsion Corporation, a leading oncology drug development company, today announced that ThermoDox in combination with radiofrequency ablation (RFA) did not meet the primary endpoint of the Phase III HEAT Study in patients with hepatocellular carcinoma (HCC), also known as primary liver cancer.

31 Jan 2013

FDA approves Biotest's BIVIGAM to treat Primary Humoral Immunodeficiency

Biotest Pharmaceuticals Corporation (BPC), a wholly owned U.S. subsidiary of Biotest AG, recently announced the U.S. Food and Drug Administration's (FDA) approval of BIVIGAM, its new intravenous immune globulin, for the treatment of patients with Primary Humoral Immunodeficiency (PI).

31 Jan 2013

Top-line results from Vanda's tasimelteon Phase IIb/III study on major depressive disorder

Vanda Pharmaceuticals Inc. today announced top-line results of the Phase IIb/III clinical study (MAGELLAN) in Major Depressive Disorder (MDD), investigating the efficacy and safety of tasimelteon as a monotherapy in the treatment of patients with MDD.

31 Jan 2013

FDA allows Arteriocyte to commence Magellan System Phase I trial in thermal burn wounds

Arteriocyte, a leading biotechnology company with offices in Cleveland, Ohio and Hopkinton, Massachusetts announced today approval from the Food and Drug Administration (FDA) to initiate a Phase I clinical trial using its Magellan System technology in the treatment of thermal burn wounds.

31 Jan 2013

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

The U.S. Food and Drug Administration recently announced the authorization of FerriScan R2-MRI to be marketed as an imaging companion diagnostic device for the safe and effective use of Exjade in patients with non-transfusion-dependent thalassemia.

31 Jan 2013

Adults should consume less than 5 g of salt and at least 3,510 mg of potassium per day: WHO

Adults should consume less than 2,000 mg of sodium, or 5 grams of salt, and at least 3,510 mg of potassium per day, according to new guidelines issued by the WHO. A person with either elevated sodium levels and low potassium levels could be at risk of raised blood pressure which increases the risk of heart disease and stroke.

31 Jan 2013

Food News and Research

PKCζ protein plays a critical role in regulating tumor metabolism

Alleviation of global hunger an urgent agenda for world leaders in 2013

Modafinil may help some people to reduce drinking by improving their impulse control

Research roundup: Concerns about ambulance diversions; The health law's impact on nursing homes; Mental health parity

FDA announces federal judge approval of Ben Venue consent decree

Dairy intake may increase risk of bone mineral density in the hip

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

New CT system reduces radiation exposure in patients undergoing CCTA

Possible link between outdoor food ads and a tendency to pack on pounds

Gates Foundation, German government, private sector to pool $108M to reduce malnutrition globally

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Galectin submits GR-MD-02 IND application with FDA for treatment of liver fibrosis

Mental health in young people: an interview with Professor Colum Dunne

ArQule, Daiichi Sankyo initiate enrollment in tivantinib Phase 3 trial for hepatocellular carcinoma

Celsion's ThermoDox does not meet primary endpoint in Phase III HCC study

FDA approves Biotest's BIVIGAM to treat Primary Humoral Immunodeficiency

Top-line results from Vanda's tasimelteon Phase IIb/III study on major depressive disorder

FDA allows Arteriocyte to commence Magellan System Phase I trial in thermal burn wounds

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

Adults should consume less than 5 g of salt and at least 3,510 mg of potassium per day: WHO

Understanding cultivated meat and its global potential eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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