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Strong placebo response key to adolescent migraine trial failures

A strong response to placebo is the main reason drug trials in the treatment of adolescent migraine have so far failed, say researchers.

31 Jan 2013

Selenium supplements do not reduce risk of developing heart disease according to current evidence

A systematic review published today in The Cochrane Library finds that in well-nourished adults current evidence does not support selenium for preventing heart disease.

31 Jan 2013

Finding medical applications for unused inventions: an interview with Gabriel Mecklenburg, Co-Founder of Marblar

Marblar is gamifying the process of technology transfer. We post technology on our platform in the form of a challenge, and the Marblar community then competes to uncover new problems these technologies could solve – thereby discovering new market applications for these technologies.

31 Jan 2013

Kemwell Biopharma’s Oral Solids manufacturing facility completes USFDA inspection

Kemwell Biopharma Pvt. Ltd., a global pharmaceutical contract development and manufacturing company, announced today that its Oral Solids manufacturing facility located in Bangalore, India has successfully completed a U.S. Food and Drug Administration (USFDA) inspection.

31 Jan 2013

Overview on dioxins

Dioxins are a group of relatively stable lipophilic organic substances. They are formed in small amounts during the combustion of organic materials and also in the manufacture of certain chemicals. They may be present in foods and feeds at low but measurable values and in highly variable amounts, and they have been associated with a number of possible negative biological effects.

31 Jan 2013

Pipeline embolization device safe and effective tool for patients with brain aneurysms

A multi-center study supports the effectiveness of the newest technology available for the treatment of difficult, life-threatening brain aneurysms. The technology, the Pipeline embolization device, is a flow diverter that redirects blood flow away from wide-necked or giant aneurysms that cannot be treated in more conventional ways.

31 Jan 2013

Study shows how gut microbes conspire with poor diets to trigger childhood malnutrition

A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition.

31 Jan 2013

Genentech announces positive results from GA101 plus chlorambucil Phase III study on CLL

Genentech, a member of the Roche Group, today announced positive results from Stage 1 of CLL11, a Phase III randomized study to investigate the efficacy and safety profile of the investigational medicine obinutuzumab (GA101) plus chlorambucil chemotherapy compared with chlorambucil alone in people with previously untreated chronic lymphocytic leukemia (CLL).

31 Jan 2013

Enzymes may have new role as intelligent micro and nanomotors

Enzymes, workhorse molecules of life that underpin almost every biological process, may have a new role as "intelligent" micro- and nanomotors with applications in medicine, engineering and other fields.

31 Jan 2013

Mayo Clinic cardiologists offer simple tips to reduce risk of heart disease

February is American Heart Month, a perfect time to remind people that small steps can reduce their risk of heart disease, the No. 1 killer of men and women. Mayo Clinic cardiologists offer several simple tips to reduce the risk.

31 Jan 2013

IL-13 protein could be the key to development of fibrosis in Crohn's disease

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease.

30 Jan 2013

Inflammation could hinder energy intake in advanced cancer

Energy intake, particularly energy density, is positively associated with energy balance in patients with advanced cancer, report Swedish researchers.

30 Jan 2013

Timing of meals predicts weight-loss effectiveness

Most weight-loss plans center around a balance between caloric intake and energy expenditure. However, new research has shed light on a new factor that is necessary to shed pounds: timing. Researchers from Brigham and Women's Hospital (BWH), in collaboration with the University of Murcia and Tufts University, have found that it's not simply what you eat, but also when you eat, that may help with weight-loss regulation.

30 Jan 2013

Clarient adopts QIAGEN’s therascreen KRAS test to diagnose colorectal cancer

QIAGEN N.V. today announced that Clarient - a GE Healthcare Company and leading provider of cancer laboratory testing services in the United States - has adopted the use of the therascreen KRAS RGQ PCR Kit (therascreen KRAS test) as a companion diagnostic to guide the use of Erbitux (cetuximab) as a treatment in patients with metastatic colorectal cancer.

From QIAGEN Manchester Limited 30 Jan 2013

Considerably smaller snack portions satisfy delayed hunger and craving

How much chocolate would you need to eat to be satisfied? Less than half as much as you think, according to this recently published Cornell University snacking study. Using chocolate chips, apple pie, and potato chips, researchers Ellen van Kleef, Mitsuru Shimizu, and Brian Wansink designed a study to determine if people who were given smaller portions of snack foods would feel hungrier or satisfied fifteen minutes after eating.

30 Jan 2013

Molecular genetics expert wins Wolf Prize for his contribution to humanity

Joachim Messing, among the world's top experts in molecular genetics, became famous for developing a genetic engineering technique used in laboratories to create plants that have produced disease-resistant crops considered vital to feeding the world's population.

30 Jan 2013

Dilaforette receives approval to initiate sevuparin Phase II malaria study in India

Dilaforette, a Karolinska Development portfolio company, today announces that the company has approval from the regulatory authority in India to start a Phase II study with sevuparin in patients with moderate to severe malaria.

30 Jan 2013

U.N. calls for additional funding for humanitarian response in Syria

"As fighting continues in Syria's civil war, the United Nations has said that it will be forced to cut already reduced food rations to hundreds of thousands of refugees unless a huge cash injection is found," Al Jazeera reports.

30 Jan 2013

Hydrogen sulfide may play a wide-ranging role in staving off aging

Hydrogen sulfide (H2S) may play a wide-ranging role in staving off aging, according to a paper published online ahead of print in the journal Molecular and Cellular Biology.

30 Jan 2013

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins - known as Src - leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature Communications that beta blocker drugs mitigate this effect and reduce cancer deaths by an average of 17 percent.

30 Jan 2013