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Combination of two compounds found in red grapes, oranges could treat diseases

A combination of two compounds found in red grapes and oranges could be used to improve the health of people with diabetes, and reduce cases of obesity and heart disease.

12 May 2016

New UHPLC columns and solvents provide advanced separation power, speed of analysis

Researchers working with complex samples can now benefit from new UHPLC columns and solvents that are designed to provide advanced separation power, speed of analysis and throughput.

From Thermo Fisher Scientific Inc. 12 May 2016

Scientists identify new hots pots of antibiotic resistance

Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of antibiotic resistance.

12 May 2016

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

12 May 2016

Scientists find tau protein as better marker of Alzheimer's disease

A buildup of plaque and dysfunctional proteins in the brain are hallmarks of Alzheimer's disease. While much Alzheimer's research has focused on accumulation of the protein amyloid beta, researchers have begun to pay closer attention to another protein, tau, long associated with this disease but not studied as thoroughly, in part, because scientists only recently have developed effective ways to image tau.

12 May 2016

Researchers discover true Diels-Alder enzyme on the Pacific seabed

Scientists at the Universities of Bristol and Newcastle have uncovered the secret of the 'Mona Lisa of chemical reactions' - in a bacterium that lives at the bottom of the Pacific Ocean.

12 May 2016

Study explores neurological mechanisms in action during ketamine anesthesia

It's a topic that has long captivated doctors, scientists and the public — what exactly happens in your brain when you're oblivious on the operating table?

12 May 2016

Comprehensive genomic characterizations of ACC provide potentially better treatment options

An international team of scientists, including those at the Translational Genomic Research Institute (TGen), have discovered new avenues of potential treatments for a rare and deadly cancer known as Adrenocortical Carcinoma, or ACC.

11 May 2016

Fast, new way to rule out potentially dangerous drugs using optogenetics

A team of researchers at the George Washington University has developed a faster method to predict whether potential new drugs will cause heart arrhythmias using optogenetics, a technique that uses light to control cells.

11 May 2016

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes.

11 May 2016

Human gut model HuMiX represents actual conditions, processes that occur within intestines

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria.

11 May 2016

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Repeat intravenous treatment with low doses of the anesthetic drug ketamine quickly reduced suicidal thoughts in a small group of patients with treatment-resistant depression.

11 May 2016

Graphene flakes can modulate synapses

The laboratory of SISSA's Laura Ballerini in collaboration with the University of Trieste, the University of Manchester and the University of Castilla -la Mancha, has discovered a new approach to modulating synapses.

11 May 2016

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons.

11 May 2016

MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

Scientists at the Montreal Neurological Institute and Hospital have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this debilitating disease.

11 May 2016

Scientists make breakthrough in understanding senses of touch and movement

Scientists investigating the little-understood senses of touch and movement have made a breakthrough that could eventually benefit people with movement disorders, spinal injuries, high blood pressure and even improve the design of robotics and prosthetics.

11 May 2016

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Oxford spinout EvOx Therapeutics will harness the body’s own precision communications system to deliver drugs to specific parts of the body, with the aim of treating conditions which are currently untreatable including those affecting the brain, as well as autoimmune diseases and cancers.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research, an American Heart Association journal.

11 May 2016

Osaka University researchers find way for early detection of AD

Kichitaro Nakajima, a graduate student at the Graduate School of Engineering Science, Hirotsugu Ogi, Associate Professor at the Graduate School of Engineering Science, and Yuji Goto, Professor at Institute for Protein Research, Osaka University succeeded in increasing the velocity constant for a reaction in which proteins causing Alzheimer disease (AD) turn into toxic substances to 1,000 times by using optimum frequency of ultrasonic irradiation.

11 May 2016

Drugs News and Research

Combination of two compounds found in red grapes, oranges could treat diseases

New UHPLC columns and solvents provide advanced separation power, speed of analysis

Scientists identify new hots pots of antibiotic resistance

Brazilian strain of Zika virus can cause severe birth defects

Scientists find tau protein as better marker of Alzheimer's disease

Researchers discover true Diels-Alder enzyme on the Pacific seabed

Study explores neurological mechanisms in action during ketamine anesthesia

Comprehensive genomic characterizations of ACC provide potentially better treatment options

Fast, new way to rule out potentially dangerous drugs using optogenetics

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Human gut model HuMiX represents actual conditions, processes that occur within intestines

Repeat, low-dose ketamine infusions may quickly reduce suicidal thoughts in depressed outpatients

Graphene flakes can modulate synapses

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

Scientists make breakthrough in understanding senses of touch and movement

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Chronic use of antacid drugs may speed up aging of blood vessels

Osaka University researchers find way for early detection of AD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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