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Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.

16 Dec 2019

Researchers receive £750,000 contract to investigate the use of laser light in animal research

Researchers at King's College London and the University of Southern Denmark have received a research contract of £750,000 to investigate the use of laser light in animal research.

16 Dec 2019

New concepts for efficient, reliable risk assessment of nanomaterials

From dyes to construction materials, and from cosmetic products to electronics and medicine, nanomaterials are found in many different applications. But what are these materials? "Nanomaterials are defined purely by their size," explains Dr Kristin Schubert from the Department of Molecular Systems Biology at UFZ.

16 Dec 2019

Modifying a cancer drug has created a new agent for multi-resistant infections

Researchers have modified a cancer drug to create an agent that is effective at treating multi-drug-resistant infections.

16 Dec 2019

Important discovery about male infertility could lead to new treatments

Using a new mouse model, Penn Medicine researchers have identified defects in the sperm epigenome that cause male infertility.

16 Dec 2019

New gene technology shows 100-fold efficiency in targeting antibiotic-resistant bacteria

Taking advantage of powerful advances in CRISPR gene editing, scientists at the University of California San Diego have set their sights on one of society's most formidable threats to human health.

16 Dec 2019

New Method of Creating Synthetic DNA Nanopores

A team has created a synthetic DNA nanopore that can translocate protein-sized macromolecules across lipid bilayers selectively.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Detection of mouth, throat cancer through saliva testing could become reality

Cancer of the throat and mouth (oropharyngeal cancers, OPC) are common, and are increasing in incidence especially among younger people. However, these are difficult to diagnose as they are not seen either by the patient or during routine medical examinations.

15 Dec 2019

Oversleeping puts you at risk of stroke

Stroke is one of the leading causes of mortality in the United States. A new study has found that sleeping too much, such as sleeping nine hours a day and having frequent naps may increase the risk of this cardiovascular disease.

15 Dec 2019

Novel HIV vaccine shows promise

There are millions living with HIV and researchers have been working towards making a successful vaccine against the deadly infection for the past 35 years with no success. Now a new blueprint is being developed to prevent the infection.

15 Dec 2019

Salk researchers uncover new function of mitochondria

Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off molecular alarms when cells are exposed to stress or chemicals that can damage DNA, such as chemotherapy.

15 Dec 2019

New structure for HIV-1 viral shell proposed

The matrix shell of the HIV-1 virus may have a different shape than previously thought, and a newly proposed model has significant implications for understanding how the virus functions, according to a new study by University of Alberta scientists.

14 Dec 2019

CSHLP releases new book on 'Metastasis: Mechanism to Therapy'

Cold Spring Harbor Laboratory Press announced the release of Metastasis: Mechanism to Therapy, available on its website in Hardcover format.

14 Dec 2019

New techniques could help neuroscientists track brain computations

Since the 1950s at least, researchers have speculated that the brain is a kind of computer in which neurons make up complex circuits that perform untold numbers of calculations every second. Decades later, neuroscientists know that these brain circuits exist, yet technical limitations have kept most details of their computations out of reach.

14 Dec 2019

Using new high-resolution imaging to track titin in real time

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into muscle development as well as treating damaged muscles and heart disease.

14 Dec 2019

New study improves understanding of widespread diseases

When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process.

14 Dec 2019

Researchers identify novel genes associated with severity of peanut allergy

Researchers at the Icahn School of Medicine at Mount Sinai have identified novel genes associated with the severity of peanut allergy, as well as ways in which these genes interact with other genes during allergic reactions.

14 Dec 2019

International project to preserve genetic resources of birds

The support is provided by the Russian Foundation for Basic Research and the Science and Innovation in East Asia Consortium. Kazan Federal University's partners are Mahidol University and Kumamoto University.

14 Dec 2019

Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is effective and well-tolerated against advanced ROS1 and NTRK fusion-positive non-small cell lung cancers (NSCLC).

14 Dec 2019