Central Nervous System News and Research

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FDA's PDAC supports use of Brintellix for treating cognitive dysfunction in adults with MDD

Takeda Pharmaceutical Company Limited and H. Lundbeck A/S today announced that the U.S. Food and Drug Administration’s Psychopharmacologic Drugs Advisory Committee voted 8 to 2 that the companies presented substantial evidence to support the effectiveness of Brintellix (vortioxetine) for treating certain aspects of cognitive dysfunction in adults with Major Depressive Disorder (MDD).

5 Feb 2016

New approach to investigate how neurodevelopment influences diseases in adulthood

The Research Training Group, which builds on translational research training programmes and research structures such as the Molecular Medicine degree programme and the Interdisciplinary Centre for Clinical Research, will work on areas where basic research and clinical practice overlap. It will bring together 20 doctoral candidates from the natural sciences and 28 from medicine.

3 Feb 2016

TPC reports first cases of illness, deaths due to Dewshine mixture in Tennessee

A lethal concoction of racing fuel and Mountain Dew claimed the lives of two Tennessee teens and has sparked the Tennessee Poison Center to warn about the lethality of what has been called "Dewshine."

1 Feb 2016

Research offers novel insights into root causes of schizophrenia

Schizophrenia is a mysterious and devastating disorder that afflicts one percent of the adult population worldwide. Its symptoms — hallucinations, emotional withdrawal, and cognitive impairment — are chronic and typically emerge just as individuals are entering adulthood. Today's medications treat just one of these symptoms (psychosis); treatments for the underlying disease and its many other symptoms have been hard to develop, because no one really understands what causes the disorder.

31 Jan 2016

Clinicoradiological syndromes allow rapid recognition of EV71 neurological problems

Severe enterovirus 71 neurological disease in children predominantly involves the spinal cord and brainstem and can be quickly recognised using the World Health Organisation classification of clinicoradiological syndromes, study findings suggest.

29 Jan 2016

Researchers create new neuronal connections for the first time

That very fine hair-line object that you see being pulled across the screen is actually a neuron being made. A research team led by McGill University and the Montreal Neurological Institute has managed to create new functional connections between neurons for the first time. Apart from the fact that these artificial neurons grow over 60 times faster than neurons naturally do, they are indistinguishable from ones that grow naturally in our bodies.

29 Jan 2016

Neurocutaneous disorders affect skin, nervous system

One of the most common genetic disorders is a condition called neurofibromatosis, which causes brown spots on the skin and benign tumors on the brain, spinal cord and other parts of the nervous system.

25 Jan 2016

Positive bosutinib response for elderly blast phase CML patient

A case study suggests that the third-generation tyrosine kinase inhibitor bosutinib may be considered as induction therapy for blast phase chronic myeloid leukaemia in older patients.

22 Jan 2016

Oxeia accelerating development of neurometabolic treatments for concussions

Oxeia Biopharmaceuticals, Inc., a biotechnology company, is catalyzing the development of first-in-class neurometabolic treatments for concussions and other aspects of brain injury.

21 Jan 2016

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Hematology researchers have used a single injection of gene therapy to correct a rare bleeding disorder, factor VII deficiency, in dogs. This success in large animals holds considerable potential for a safe, effective and long-lasting new treatment in humans with the same bleeding disorder.

21 Jan 2016

Upsher-Smith, Saniona sign drug discovery and development agreement

Upsher-Smith Laboratories, Inc., through its wholly-owned subsidiary Proximagen Ltd., and Saniona, a leading biotech company in the field of ion channels, today announce that they have entered into a drug discovery and development collaboration.

20 Jan 2016

Physiotherapy and occupational therapy not effective in patients with Parkinson's disease

New research from the University of Birmingham has shown that physiotherapy and occupational therapy do not produce improvements in quality of life for patients with mild to moderate Parkinson's disease.

20 Jan 2016

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

In recent time, many epidemiological studies have proved very close links existing between diabetes and Alzheimer´s disease. In fact, it has been stated that diabetes is a significant risk factor for suffering from Alzheimer and vascular dementia, the two main causes of dementia.

12 Jan 2016

Salk Institute scientists find new target for glioblastoma multiforme treatment

Glioblastoma multiforme is a particularly deadly cancer. A person diagnosed with this type of brain tumor typically survives 15 months, if given the best care. The late Senator Ted Kennedy succumbed to this disease in just over a year.

11 Jan 2016

UC San Diego School of Medicine study compares payments among different specialties

The Physician Payments Sunshine Act, passed under the Affordable Care Act, requires all pharmaceutical and medical device companies to report payments to physicians, including consulting fees, gifts, speaking fees, meals, travel and research grants. This information is searchable to the public on a database called Open Payments, managed by the Centers for Medicare & Medical Services.

6 Jan 2016

Scientists demonstrate workings of CCL2 mechanism that stimulates nerve regeneration

The peripheral nervous system is a vast network of nerves that exists primarily outside of brain and spinal cord and connects to the far reaches of the body. The very expanse of peripheral nerves makes them highly vulnerable to injuries such as blunt-force blows, cuts, and leg and arm fractures, as well as diseases that attack peripheral nerves such as diabetes, Charcot-Marie-Tooth, and Guillain-Barre syndrome.

6 Jan 2016

Central Nervous System News and Research

FDA's PDAC supports use of Brintellix for treating cognitive dysfunction in adults with MDD

New approach to investigate how neurodevelopment influences diseases in adulthood

TPC reports first cases of illness, deaths due to Dewshine mixture in Tennessee

Research offers novel insights into root causes of schizophrenia

Clinicoradiological syndromes allow rapid recognition of EV71 neurological problems

Researchers create new neuronal connections for the first time

Neurocutaneous disorders affect skin, nervous system

Positive bosutinib response for elderly blast phase CML patient

Oxeia accelerating development of neurometabolic treatments for concussions

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Upsher-Smith, Saniona sign drug discovery and development agreement

Physiotherapy and occupational therapy not effective in patients with Parkinson's disease

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

Salk Institute scientists find new target for glioblastoma multiforme treatment

UC San Diego School of Medicine study compares payments among different specialties

Scientists demonstrate workings of CCL2 mechanism that stimulates nerve regeneration

CAMH researchers identify 428 distinct disease conditions that co-occur in people with FASD

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

Araim Pharmaceuticals forms new strategic collaboration with Vault Bioventures to market novel peptides

Personalised approach may help identify patients’ response to certain cancer treatments

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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