Central Nervous System News and Research

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Kanazawa University researchers identify molecular mechanism that links liver disease and obesity

Kanazawa University researchers find similarities in the impeded signalling between central insulin activity and glucose production in the liver for both obese mice and mice that have had the vagus nerve removed.

16 Mar 2016

Neural stem cells from T cell-derived iPSCs provide neurological disease model

Researchers in Japan report that neural stem cells derived from readily available T cell-derived iPSCs provide a neurological disease model when cultured in a novel protocol developed by them. The findings are important for the treatment of Parkinson’s disease and are published in Stem Cell Reports, March 2016.

16 Mar 2016

Scientists sort out mechanism of Alzheimer's disease development

A group of the Lomonosov Moscow State University scientists, together with their colleagues from the Institute of Molecular Biology, Russian Academy of Sciences and the King's College London, succeeded in sorting out the mechanism of Alzheimer's disease development and possibly distinguished its key trigger.

11 Mar 2016

Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

The research thoroughly reviews the importance of the blood-brain barrier (BBB) and the blood-tumor barrier (BTB) along with the current status and future perspectives of interesting physical and surgical strategies to circumvent these central nervous system (CNS) barriers in the treatment of malignant brain tumors.

10 Mar 2016

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). Although 5-HT is predominantly known as a neurotransmitter within the central nervous system, new evidence points to additional important functions for serotonin in the periphery.

10 Mar 2016

New discoveries reveal why smokers have increased risk of type 2 diabetes

Researchers at Lund University in Sweden have made two new discoveries with regard to the beta cells' ability to release insulin. The findings can also provide a possible explanation as to why smokers have an increased risk of type 2 diabetes.

9 Mar 2016

Immune cells play vital role in rewiring connections between nerve cells

A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells.

8 Mar 2016

Zika virus can cause a range of abnormalities in pregnant women, study finds

New research presents strong evidence that the Zika virus can indeed cause a range of abnormalities in pregnant women infected with the virus -- with the effects manifesting any time during pregnancy. Some of the abnormalities noted have not been reported in connection with the virus.

7 Mar 2016

Drinking more coffee may reduce risk of multiple sclerosis

Drinking a lot of coffee every day--more than 900 ml (30 fluid ounces) or around six cups--is linked to a reduced risk of multiple sclerosis (MS), finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

7 Mar 2016

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016

Promising therapeutic strategy for relieving neuropathic pain

A specific molecule involved in maintaining pain after a nerve injury has been identified and blocked in mice by Hiroshima University researchers. These results reveal a promising therapeutic strategy for treating neuropathic pain.

1 Mar 2016

Rockefeller research reveals vital new component of system responsible for regulating food intake

The molecular intricacies of hunger and satiety, pivotal for understanding metabolic disorders and the problem of obesity, are not yet fully understood by scientists. However, new research from The Rockefeller University reveals an important new component of the system responsible for regulating food intake: a hormone called amylin, which acts in the brain to help control consumption.

27 Feb 2016

New drug shows promise against Huntington's disease

A drug that would be the first to target the cause of Huntington's disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

27 Feb 2016

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

An international research team has identified four likely new subtypes of a rare brain tumor using molecular techniques that lay the foundation for more accurate diagnosis and tailored therapies for the hard-to-treat cancer. Scientists at St. Jude Children's Research Hospital and the German Cancer Research Center led the study, results of which appear today in the scientific journal Cell.

26 Feb 2016

New report reveals malignant brain tumors as most common cause of cancer-related deaths in young people

A new report published in the journal Neuro-Oncology and funded by the American Brain Tumor Association finds that malignant brain tumors are the most common cause of cancer-related deaths in adolescents and young adults aged 15-39 and the most common cancer occurring among 15-19 year olds.

25 Feb 2016

Vertical Pharmaceuticals launches breakthrough prenatal vitamin supplement: OB Complete Gold

OB Complete Gold is a breakthrough innovation in prenatal vitamin supplements that contains the advanced technology OmEGGa DHA, providing a novel egg-based DHA that comes from cage-free hens.

25 Feb 2016

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Cancer immunology is based upon boosting the body's own immune system to vanquish malignancies. It is among the fastest growing areas of oncology research. Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells - one of the immune system's primary weapons - to treat three different types of blood cancer that often defy existing therapies.

24 Feb 2016

Gamma Knife and RapidArc equally effective at eradicating cancer in the brain

While two advanced radiosurgery approaches — Gamma Knife and RapidArc — offer different strengths, they are equally effective at eradicating cancer in the brain, say researchers at Sidney Kimmel Cancer Center.

24 Feb 2016

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Researchers at the Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona (IBB-UAB), in collaboration with the biopharmaceutical company SOM Biotech, located in the Barcelona Science Park (PCB), have published, in Nature Communications, the results of a drug repositioning study in which they describe a powerful drug, SOM0226 (tolcapone) that could significantly improve the pharmacological treatment of familial transthyretin amyloidosis (ATTR).

24 Feb 2016

Longer, more intense period of rehabilitation may boost recovery after stroke or traumatic injury

Cognitive and functional recovery after a stroke or traumatic injury requires intense rehabilitative therapy to help the brain repair and restructure itself. New findings by researchers at University of California, San Diego School of Medicine report that not only is rehabilitation vital - in an animal model, rats with cortical injury that did not receive intensive rehab did not rebuild brain structure or recover function - but that a longer, even more intense period of rehabilitation may produce even greater benefit.

23 Feb 2016

Central Nervous System News and Research

Kanazawa University researchers identify molecular mechanism that links liver disease and obesity

Neural stem cells from T cell-derived iPSCs provide neurological disease model

Scientists sort out mechanism of Alzheimer's disease development

Research reviews importance of blood-brain barrier, blood-tumor barrier in treatment of brain tumors

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

New discoveries reveal why smokers have increased risk of type 2 diabetes

Immune cells play vital role in rewiring connections between nerve cells

Zika virus can cause a range of abnormalities in pregnant women, study finds

Drinking more coffee may reduce risk of multiple sclerosis

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

Promising therapeutic strategy for relieving neuropathic pain

Rockefeller research reveals vital new component of system responsible for regulating food intake

New drug shows promise against Huntington's disease

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

New report reveals malignant brain tumors as most common cause of cancer-related deaths in young people

Vertical Pharmaceuticals launches breakthrough prenatal vitamin supplement: OB Complete Gold

Researchers launch clinical trials to test novel cellular-immunotherapy to treat three types of blood cancer

Gamma Knife and RapidArc equally effective at eradicating cancer in the brain

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Longer, more intense period of rehabilitation may boost recovery after stroke or traumatic injury

Event guide: The 7th CNS Drug Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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