Clinical Trial News and Research

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Review finds no proven clinical benefit to strict salt restriction for patients with heart failure

For decades, it's been thought that people with heart failure should drastically reduce their dietary salt intake, but some studies have suggested that salt restriction could be harmful for these patients.

26 Jun 2024

Extended-release ketamine tablets offer new hope for treatment-resistant depression

The BEDROC trial found that extended-release ketamine tablets (R-107) significantly improve depressive symptoms in treatment-resistant depression patients, with the 180 mg dose showing the most efficacy. The treatment was well-tolerated with minimal side effects.

26 Jun 2024

Prunes may protect bone structure and strength in postmenopausal women, study reveals

Dairy isn't the only food that's good for bone health. Prunes may also protect bone structure and strength in postmenopausal women, according to a new study led by Penn State researchers.

25 Jun 2024

New curative treatment for sickle cell disease shows promising results in international trial

Vanderbilt University Medical Center (VUMC) researchers are touting data from a multicenter, international phase 2 clinical trial showing a new, curative treatment for sickle cell disease (SCD).

25 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

New research challenges current practices for premature babies

Giving very premature babies high concentrations of oxygen soon after birth may reduce the risk of death by 50 percent, compared to lower levels of oxygen says new research led by University of Sydney researchers.

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

First child receives skull-mounted epilepsy device in UK clinical trial

Oran, who had been having severe epileptic seizures for eight years and often needed resuscitation, was the first child in the UK to have this device implanted at Great Ormond Street Hospital in October 2023, when he was 12 years old.

24 Jun 2024

Mouse studies suggest gestational CBD exposure alters offspring behavior and brain function

Cannabidiol (CBD), one of the active ingredients in cannabis, is thought to be safe as it does not cause a "high".

24 Jun 2024

New ketamine slow-release tablet shows promise in treating severe depression

A new tablet form of ketamine has shown promise in treating severe depression, offering a potential alternative to existing clinic-based treatments that can be expensive and lacking in convenience for some patients.

24 Jun 2024

Ketamine tablets offer new hope for treatment-resistant depression

For those suffering from treatment-resistant depression, the anaesthetic drug ketamine offers hope, but it has side effects and can be costly to access – a University of Otago-led clinical trial may change that.

24 Jun 2024

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

UQ-led project to test technology-driven solutions for rural skin cancer screening

A University of Queensland-led project will test a combination of technologies to improve the early detection of potentially fatal skin cancers in patients in regional and rural Australia.

24 Jun 2024

Intermittent fasting outperforms traditional drugs in managing early type 2 diabetes

Study shows that a 5:2 intermittent fasting meal replacement diet effectively controls blood glucose levels and reduces body weight in Chinese adults with early type 2 diabetes. This dietary intervention outperforms metformin and empagliflozin in managing diabetes and obesity.

24 Jun 2024

Mindfulness meditation curbs gaming addiction by altering brain responses

Mindfulness meditation significantly reduces gaming cravings and addiction severity in adults with Internet Gaming Disorder. The study reveals decreased activation in brain regions associated with craving, such as the lentiform nuclei and medial frontal gyrus.

23 Jun 2024

Novo Nordisk presents key findings from semaglutide trials at ADA scientific sessions 2024

Novo Nordisk today announced the presentation of 34 abstracts highlighting the breadth of its portfolio at the upcoming 84th Scientific Sessions of the American Diabetes Association (ADA).

22 Jun 2024

Transforming care for rheumatoid arthritis patients through symptom monitoring

Researchers at The University of Manchester are to trial a system that allows people living with rheumatoid arthritis to send their daily symptoms securely to their health record, in a first for the NHS.

22 Jun 2024

Tirzepatide emerges as first drug therapy for obstructive sleep apnea

Researchers at University of California San Diego School of Medicine and international collaborators have led a worldwide, advanced study demonstrating the potential of tirzepatide, known to manage type 2 diabetes, as the first effective drug therapy for obstructive sleep apnea (OSA), a sleep-related disorder characterized by repeated episodes of irregular breathing due to complete or partial blockage of the upper airway.

21 Jun 2024

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy has shown great promise as a new strategy against advanced lung cancer, based on results from a small clinical trial led by investigators at the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine.

21 Jun 2024

Combination therapy shows great promise as a new strategy against advanced lung cancer

21 Jun 2024

Clinical Trial News and Research

Review finds no proven clinical benefit to strict salt restriction for patients with heart failure

Extended-release ketamine tablets offer new hope for treatment-resistant depression

Prunes may protect bone structure and strength in postmenopausal women, study reveals

New curative treatment for sickle cell disease shows promising results in international trial

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

New research challenges current practices for premature babies

MicroRNAs shed light on aggressive youthful type 2 diabetes

First child receives skull-mounted epilepsy device in UK clinical trial

Mouse studies suggest gestational CBD exposure alters offspring behavior and brain function

New ketamine slow-release tablet shows promise in treating severe depression

Ketamine tablets offer new hope for treatment-resistant depression

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

UQ-led project to test technology-driven solutions for rural skin cancer screening

Intermittent fasting outperforms traditional drugs in managing early type 2 diabetes

Mindfulness meditation curbs gaming addiction by altering brain responses

Novo Nordisk presents key findings from semaglutide trials at ADA scientific sessions 2024

Transforming care for rheumatoid arthritis patients through symptom monitoring

Tirzepatide emerges as first drug therapy for obstructive sleep apnea

JAK1 inhibition and Anti-PD1 therapy enhance outcomes in advanced lung cancer

Combination therapy shows great promise as a new strategy against advanced lung cancer

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