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Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

One in 7 (14%) adults with coronavirus infection developed at least one new condition that required medical care during the post-acute phase of illness, which is 5% higher than adults with no coronavirus infection in 2020, finds a US study published by The BMJ today.

21 May 2021

Study analyzes the risk of other medical conditions after recovery from COVID-19

Researchers analyzed data from a large insurance company in the United States. They found an increased risk of other medical conditions after recovering from COVID-19 irrespective of pre-existing conditions or age.

21 May 2021

Plant-produced COVID-19 vaccine shows potent immunogenic profile in humans

An interim report on a phase 2 clinical trial indicates both the safety and efficacy of a plant-produced virus-like particle vaccine candidate against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vaccine candidate has shown an acceptable safety profile and high potency in inducing humoral and cellular immune responses in adults (18 – 64 years) and elderly (65 years and above) individuals. The report is currently available on the medRxiv* preprint server.

20 May 2021

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Four months of multi-drug therapy that included rifapentine and moxifloxacin treated active tuberculosis (TB) as effectively as the standard six-month regimen in a multinational study, cutting treatment time by a third.

20 May 2021

Study addresses “leaky pipeline” that prevents Black medical students in reaching their residency goals

Self-affirmation, the practice of reflecting upon one's most important values, can aid Black medical students in reaching their residency goals. But conversely, it can lead to the perception that they are less qualified for a prestigious residency than their peers.

20 May 2021

New pan-European survey explores the effect of COVID-19 restrictions on physical, mental health

A new pan-European survey funded by the Institute for Scientific Information on Coffee exploring the impact of COVID-19 Lockdowns and associated restrictions (in those countries where there has been no Lockdown), has found that nearly two thirds of adults (61%) expressed concern about their worsening mood; two times higher than those concerned about physical inactivity (24%).

20 May 2021

Despite sufficient information on COVID-19, Central PA residents worry about mixed messages

Residents of central Pennsylvania had the information they needed to slow the spread of COVID-19 early on in the pandemic, but were overwhelmed with worries about mixed messages and distrust of some sources, according to Penn State College of Medicine researchers.

19 May 2021

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.

18 May 2021

A possible human-to-canine transmission of SARS-CoV-2

Now, researchers at the U.S. Centers for Disease Control and Prevention (CDC) identified a case of human to animal transmission when SARS-CoV-2 was detected in a healthy poodle dog living with four family members who had COVID-19.

18 May 2021

Pirfenidone significantly reduces a marker of heart muscle scarring

Patients with heart failure with preserved ejection fraction who took the antifibrotic drug pirfenidone saw a significant reduction in a marker of heart muscle scarring compared with patients who received a placebo, based on findings from an early-phase trial presented at the American College of Cardiology's 70th Annual Scientific Session.

18 May 2021

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin-converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks.

17 May 2021

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

Preliminary clinical trial results from an ongoing Phase 2/3 trial led by Laurent M. Humeau of Inovio Pharmaceuticals suggest the two-dose INO-4800 vaccine is safe for use in adults of varying ages. The results expand on phase 1 trial results that found the vaccine was safe and tolerable in 38 participants.

16 May 2021

A look at how coronavirus disease (COVID-19) affects Parkinson's

Earlier, herpes simplex virus (HSV), influenza virus A, measles virus, cytomegalovirus (CMV), and mumps virus have all been associated with after-effects of the virus that includes Parkinson's disease (PD). This list may now include SARS-CoV-2.

14 May 2021

Huge healthcare burden of post-COVID-19 symptoms likely, suggests new study

How well do patients who had COVID-19 recover after the virus is cleared from their systems? A new preprint reports on symptom profiles over the first nine months of the illness.

13 May 2021

Pfizer-BioNTech COVID-19 vaccine effective in patients with myeloproliferative neoplasms

Researchers in the UK have provided evidence that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces effective immune responses in patients with myeloproliferative neoplasms.

13 May 2021

Case study examines prescriptions and healthcare use in non-hospitalized COVID-19 recoverers

In a new study published in The Lancet, a team of researchers examined prescription drug and healthcare use after SARS-CoV-2 infection in those who did not require hospital admission.

12 May 2021

Study reveals acute immunologic changes in children with long COVID

Many reports are beginning to emerge on the ‘long COVID’ phenomenon. But a new study, released as a preprint on the medRxiv* server, describes, for the first time, immunologic changes observed in children with PASC.

11 May 2021

Cardiac complications found to be rare in college athletes who contracted COVID-19

In a small study, researchers found college athletes who contracted COVID-19 rarely had cardiac complications. Most had mild COVID symptoms that did not require treatment, and in a small percentage of those with abnormal cardiac testing, there was no evidence of heart damage on special imaging tests.

10 May 2021

Study identifies most persistent neurological problems during long COVID-19

Neuropsychiatric issues have been frequently reported in coronavirus disease 2019 (COVID-19) long-haulers. A new study on the medRxiv* preprint server has found which neurological symptoms are likely to persist after a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

10 May 2021

Increased heart rate as a physiological response to SARS-CoV-2 mRNA vaccine

Although widely publicized, evidence for physiological responses to the vaccines is currently scarce in published literature. Giogiro Quer and Matteo Gadaleta of the Scripps Research Translational Institute in California, USA, led an investigation to obtain tracking data for physiological responses to vaccine programs.

8 May 2021

Fatigue News and Research

Researchers evaluate risk of developing new clinical conditions after acute phase of COVID-19 infection

Study analyzes the risk of other medical conditions after recovery from COVID-19

Plant-produced COVID-19 vaccine shows potent immunogenic profile in humans

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Study addresses “leaky pipeline” that prevents Black medical students in reaching their residency goals

New pan-European survey explores the effect of COVID-19 restrictions on physical, mental health

Despite sufficient information on COVID-19, Central PA residents worry about mixed messages

Western diet impairs the gut immune system, could increase risk of inflammatory bowel disease

A possible human-to-canine transmission of SARS-CoV-2

Pirfenidone significantly reduces a marker of heart muscle scarring

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

A look at how coronavirus disease (COVID-19) affects Parkinson's

Huge healthcare burden of post-COVID-19 symptoms likely, suggests new study

Pfizer-BioNTech COVID-19 vaccine effective in patients with myeloproliferative neoplasms

Case study examines prescriptions and healthcare use in non-hospitalized COVID-19 recoverers

Study reveals acute immunologic changes in children with long COVID

Cardiac complications found to be rare in college athletes who contracted COVID-19

Study identifies most persistent neurological problems during long COVID-19

Increased heart rate as a physiological response to SARS-CoV-2 mRNA vaccine

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