immunity News and Research

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B lymphocytes play a pivotal role in promoting an emergent response during infection

An SOS signals a call for immediate action during an emergency to request a need for protection. The immune system, a network of defense mechanisms, enhances protection to recover the body's internal stability.

15 Feb 2023

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Bivalent booster recipients show slightly higher protection against infection and significantly higher protection against death than monovalent booster recipients

Researchers reported the immune protection conferred by monovalent COVID-19 vaccines and bivalent booster doses.

13 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Vaccine efficacy and booster dose combinations among 18.9 million adults in the early phase of Omicron

A new study in the journal Clinical Infectious Diseases aimed to determine the relative vaccine effectiveness (rVE) in three different recipient cohorts, those who received the Ad26.COV2.S vaccine followed by Ad26.COV2.S booster, those who received the Ad26.COV2.S vaccine followed by an mRNA booster, and those who received two doses of an mRNA vaccine followed by an mRNA booster.

12 Feb 2023

Study identifies a previously unknown role of 'natural killer' immune cells

Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of 'natural killer' (NK) immune cells.

10 Feb 2023

Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

One of the most terrifying aspects of the COVID pandemic has been its unpredictably severe impact on some children.

10 Feb 2023

Is gut microbiome lipid metabolism a determinant of human health?

Researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of immunity and metabolism. Note that commensal fungal species also produce lipid metabolites.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Pegylated interferon lambda shows good efficacy against COVID-19

In a recent study published in The New England Journal of Medicine, researchers used the TOGETHER platform trial protocol to perform a phase III randomized controlled trial (RCT) to evaluate the effectiveness of pegylated interferon (IFN) lambda (λ) therapy in outpatients with coronavirus disease 2019 (COVID-19) in Canada and Brazil.

9 Feb 2023

Maternal covid-19 vaccination during pregnancy may reduce risk of hospital admission in infants

Two doses of mRNA covid-19 vaccine during pregnancy are highly effective against delta and moderately effective against omicron infection, and are linked to a lower risk of hospital admission in infants under six months of age, finds a Canadian study published by The BMJ today.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.

9 Feb 2023

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Heterologous vaccination improves the neutralization of SARS-CoV-2 Omicron sub-variants.

9 Feb 2023

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Biochemist Jon Jacobs has analyzed the blood of patients with diseases and conditions such as Ebola, cancer, tuberculosis, hepatitis, diabetes, Lyme disease, brain injury and influenza.

9 Feb 2023

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

A researchers emphasized the need to reconsider mRNA COVID-19 vaccination strategies in the future,

9 Feb 2023

Research reveals differences in the gut microbiomes of people with ME/CFS

The study was led by scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health, as part of the Center for Solutions for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, an inter-disciplinary, inter-institutional research group dedicated to understanding the biology of the disease in order to develop effective means to diagnose, treat and prevent it.

8 Feb 2023

Community engagement efforts in Alabama identify priority communities for SARS-CoV-2 testing

Researchers promote SARS-CoV-2 testing among underserved communities in rural Alabama.

8 Feb 2023

immunity News and Research

B lymphocytes play a pivotal role in promoting an emergent response during infection

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

New insights into the role of T-cells during long COVID

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Bivalent booster recipients show slightly higher protection against infection and significantly higher protection against death than monovalent booster recipients

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Vaccine efficacy and booster dose combinations among 18.9 million adults in the early phase of Omicron

Study identifies a previously unknown role of 'natural killer' immune cells

Rockefeller scientists describe the genetics of severe SARS-CoV-2 infection in children

Is gut microbiome lipid metabolism a determinant of human health?

Casein-based diet found to protect diabetic mice against autoimmunity

Pegylated interferon lambda shows good efficacy against COVID-19

Maternal covid-19 vaccination during pregnancy may reduce risk of hospital admission in infants

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Protein activity found to be more dysregulated in the blood of patients with alcohol-associated hepatitis

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

Research reveals differences in the gut microbiomes of people with ME/CFS

Community engagement efforts in Alabama identify priority communities for SARS-CoV-2 testing

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