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Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

New gene editing technique offers hope for millions

A team led by Mass Eye and Ear researchers has demonstrated for the first time a successful restoration of hearing through a novel, in vivo genome editing approach in an adult mouse model with a form of inherited deafness caused by mutations in microRNA.

11 Jul 2024

Gut bacteria-metabolized equol shows promise in cancer prevention

Researchers reviewed how soy isoflavones are metabolized by gut bacteria into equol, exploring its role in cancer prevention and treatment. They examined the molecular mechanisms and gut microbiota involved to understand equol's anti-tumor effects.

11 Jul 2024

Study finds disparities in heart bypass surgery for women

Women over the age of 65 who require complex heart surgery are more likely than men to receive care at low quality hospitals - where they also die in greater numbers following the procedure, a Michigan Medicine study finds.

11 Jul 2024

How Aloe vera's medicinal properties make it essential in medicine, cosmetics, and food products

Comprehensive review highlights Aloe vera's versatile biological activities and its potential applications in medicine and cosmetics while addressing its safety concerns.

11 Jul 2024

COVID-19 lockdown reduced childhood wheezing and bronchiolitis cases

Bronchiolitis cases dropped significantly during the COVID-19 lockdown, leading to fewer wheezing episodes and reduced respiratory medication use in children.

10 Jul 2024

Salads under scrutiny: Study reveals contamination risks and solutions in ready-to-eat salads

The research paper highlights critical contamination points in the production of ready-to-eat salads and discusses solutions to ensure microbiological safety and health.

10 Jul 2024

Scientists discover a molecular defect that promotes pathologic immune response in lupus

Northwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse the disease.

10 Jul 2024

Aging aggravates liver fibrosis in Down Syndrome, new study finds

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 12, entitled, "Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome."

10 Jul 2024

Novel molecule could inform new therapies for stroke-related brain injury

A newly developed molecule, LK-2, could inform new therapies for stroke-related brain injury, finds scientists at The Hospital for Sick Children (SickKids).

10 Jul 2024

New consortium receives NIH grant to accelerate development of effective TB treatments

A new consortium co-led by Weill Cornell Medicine, has been awarded a five-year, $31 million grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis (TB).

10 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Antibody fragment discovery could lead to much-needed treatment for light chain amyloidosis

In people with a rare condition called light chain amyloidosis, light chain proteins - which are a component of antibodies - mutate and build up in different organs.

10 Jul 2024

Chronic exposure to air pollutants may increase lupus risk, research shows

New research published in Arthritis & Rheumatology indicates that chronic exposure to air pollutants may increase the risk of developing lupus, an autoimmune disease that affects multiple organs.

10 Jul 2024

Improving acne symptoms with Mediterranean diet and omega-3 supplements

In a study in the Journal of Cosmetic Dermatology that included 60 individuals with mild to moderate acne, following the Mediterranean diet and taking omega-3 fatty acid supplements led to significant reductions in inflammatory and non-inflammatory skin lesions, as well as improved quality of life.

10 Jul 2024

Researchers uncover the incidence and prevalence of eosinophilic esophagitis in Japan

In one of the first studies of its kind in Japan, Osaka Metropolitan University-led researchers uncovered the incidence and prevalence of the chronic allergic disorder eosinophilic esophagitis, or EoE.

10 Jul 2024

Advocate Health selected for CMS GUIDE Model aimed at advancing dementia care

Advocate Health has been selected by the Centers for Medicare and Medicaid Services (CMS) to participate in the Guiding an Improved Dementia Experience (GUIDE) Model, aimed to support advanced dementia patients and their caregivers in bridging the gaps associated with inequalities in dementia care.

10 Jul 2024