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Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future influenza vaccination strategies.

13 Aug 2024

New ultrasound-based tool offers precise measurement of lung diseases

Researchers have established a suite of parameters that can be determined using ultrasound to quantitatively measure different physical characteristics of the lung.

13 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to better understand the underlying mechanisms of cardiovascular disease.

8 Aug 2024

New bioactive material regenerates high-quality cartilage in the knee joints of large-animal model

Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model.

5 Aug 2024

Vanderbilt researchers illuminate white matter signals in the spinal cord

Injuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability. Some degree of recovery may be possible. The question is, how best to stimulate the regrowth and healing of damaged nerves.

2 Aug 2024

UVA researchers identify a potential treatment for respiratory symptoms of long COVID

University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs.

30 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

New study helps better understand the pathology of fatty liver disease MASH

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

24 Jul 2024

New study sheds light on irregular heartbeat risk

Two new, basic animal research studies shed light on alcohol consumption and the heart. The first study may help explain why binge drinking sometimes causes an irregular heartbeat and a possible way to prevent it. The second study investigated why alcohol may have a negative impact on heart function in women taking estrogen replacement therapy.

23 Jul 2024

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammaging', which is widely believed to be the root cause of many age-related diseases.

18 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

New technique could one day be used to target glioblastoma

Tackling brain cancer is complicated, but groundbreaking new research could help add another tool to the cancer-fighting arsenal.

17 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Animal Model News and Research

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

New ultrasound-based tool offers precise measurement of lung diseases

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

New $11.3 million grant to explore endothelial cell dysfunction in cardiovascular disease

New bioactive material regenerates high-quality cartilage in the knee joints of large-animal model

Vanderbilt researchers illuminate white matter signals in the spinal cord

UVA researchers identify a potential treatment for respiratory symptoms of long COVID

Researchers identify a potential therapeutic target for advanced multiple sclerosis

New study helps better understand the pathology of fatty liver disease MASH

New study sheds light on irregular heartbeat risk

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

New technique could one day be used to target glioblastoma

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Researchers identify brain region that tunes hearing to contextual needs

New nanosized sensor records the electrical activity of spinal neurons

Aging aggravates liver fibrosis in Down Syndrome, new study finds

Trinity College Dublin researchers uncover key to enhancing MRSA vaccine efficacy

Animal model sheds light on the role understudied brain organ in repairing stroke damage

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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