Animal Model News and Research

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Research team identifies previously unknown ability of the autonomic nervous system

The autonomic nervous system is known as the control center for involuntary bodily processes such as the beating of our hearts and our breathing.

11 Nov 2022

High-quality reference genome assembly of the Nile rat facilitates diabetes research

Model organisms are essential for biomedical research and have enabled many important scientific discoveries. The ability to sequence the genomes of these models is a powerful tool to study the genetic factors that impact human health.

9 Nov 2022

Repeated emotional stress in mice provokes irritable bowel syndrome-like symptoms

The evidence for the interconnection between emotional states and intestinal conditions has grown recently. These findings have led researchers to speculate about the association between the brain and the gut – the "gut-brain axis."

9 Nov 2022

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52% to only 6%.

7 Nov 2022

Scientists map neural pathways that lead to vomiting after eating contaminated food

A new study describes a system by which gut-brain pathways coordinate with brain circuits to initiate nausea and vomiting.

6 Nov 2022

Researchers shed light on the key functions of innate immune cells

Inflammation and increased mucus production are typical symptoms of worm infections and allergies. This immune response involves our innate immune cells, but their exact functions are not yet fully understood.

3 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

New probe design offers promises for many imaging applications in biological and biomedical research

Microendoscopes are the cornerstone of modern medical diagnostics - they allow us to see what we could not even describe two decades ago.

28 Oct 2022

Study identifies an animal model that shares many similarities with progressive MS

A new study from UCLA researchers identified an animal model that could be used to study treatments for improving disabilities in multiple sclerosis patients.

25 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Zinc could improve the brain defects caused by rare genetic disorder

Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene.

10 Oct 2022

Scientists develop an unprecedented animal model to investigate Ewing sarcoma

Ewing sarcoma is the second most frequent bone tumour in children, adolescents, and young adults. There is no specific treatment for this disease and current management is still limited to surgery, radiotherapy, and chemotherapy.

7 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Researchers determined the T cell response to the NVX-CoV2373, an adjuvanted recombinant full-length SARS-CoV-2 spike (S) trimer protein vaccine.

5 Oct 2022

Novel linear DNA SARS-CoV-2 vaccine using electroporation-aided vaccine delivery reveals lower viral shedding in ferrets

Researchers evaluated the efficacy, immunogenicity, and safety of a novel SARS-CoV-2 linear deoxyribonucleic acid vaccine in ferret models delivered using intramuscular injection and electroporation.

3 Oct 2022

Universal vaccine advancement through AI and recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng and Dr. Lurong Pan about how AI computing can be used in combination with high throughput production and screening to enhance the development process for potential universal vaccines.

From Sino Biological Inc. 3 Oct 2022

Brain stimulation combined with nasal spray containing nanoparticles can improve stroke recovery

In a recent study, researchers from Xi'an Jiaotong-Liverpool University and other universities in China have reported that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke in an animal model.

29 Sep 2022

Study may one day lead to a new treatment for preventing cerebral palsy

Severe brain injury that develops slowly after preterm births, causing the likes of cerebral palsy, may be treatable, new research from the University of Auckland finds.