Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Acute myeloid leukemia (AML) is a cancer that affects blood cells in the bone marrow -; the spongy tissue inside certain bones, where new blood cells are made.

17 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Indiana University School of Medicine researchers have identified a promising new combination of drugs to treat juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer that affects children.

5 Apr 2023

Study explains why leukemia survivors experience negative effects on blood formation decades later

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia.

5 Apr 2023

New anticancer agent activated by ultrasound waves does not have strong side effects

Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumor tissue and is activated thereby ultrasound waves does not have this problem.

5 Apr 2023

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

With the aid of a near $3.2 million National Cancer Institute grant (R01CA277599) recently awarded, investigators from the state's leading cancer program, Rutgers Cancer Institute of New Jersey,  and Georgetown University's Lombardi Comprehensive Cancer Center, both NCI-designated Comprehensive Cancer Centers, will work to close racial disparity gaps in cancer care delivery by examining a novel approach to genetic testing and care based on community-identified needs.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

UW researchers identify a target that may make bone marrow transplants safer and more effective

A bone marrow transplant can be a lifesaving treatment for people with relapsed blood cancers, but a potentially lethal complication known as graft-versus-host disease put limitations on this procedure.

24 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

21 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

How to assess clinical response in multiple myeloma

In this interview, Cerba Research explains how its teams were able to assess clinical response in multiple myeloma (MM) patients that were receiving monoclonal antibodies treatment,

From Cerba Research 16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Bone Marrow News and Research

Further Reading

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Study highlights the potential long-term neurological effects post-COVID-19

Promising new combination of drugs identified to treat juvenile myelomonocytic leukemia

Study explains why leukemia survivors experience negative effects on blood formation decades later

New anticancer agent activated by ultrasound waves does not have strong side effects

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

Study shows how neutrophils play a key role in cancer immunotherapy success

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

How do viral infections cause autoimmune diseases?

UW researchers identify a target that may make bone marrow transplants safer and more effective

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Scientists develop a marker for therapy response in acute myeloid leukemia

How to assess clinical response in multiple myeloma

Scientists develop genetically defined mouse models for multiple myeloma subtypes

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Scientists identify the cause of leukemia in people with trisomy 21

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

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