CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

New subtype of Castleman disease identified to improve diagnosis and treatment

A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years.

22 Apr 2025

Hospitals can play key role in treating alcohol use disorder

Nearly 30 million adults in the United States experience alcohol use disorder (AUD), but the vast majority of people with this condition do not receive treatment.

21 Apr 2025

Art as a tool for well-being in everyday life

Simply looking at visual art, visiting a museum, or having art in your hospital room can enhance well-being, particularly repeated engagement, which can increase the meaning we feel in life, according to a new international study led by researchers from the University of Vienna.

16 Apr 2025

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

CellVoyant leverages AI and live-cell imaging to predict cellular behavior, transforming cell therapy development and making it more accessible and efficient.

16 Apr 2025

Why measles is back in the U.S. and what doctors must know now

Measles is making a troubling comeback in the U.S., driven by declining vaccination rates and rising vaccine hesitancy. Pediatric infectious disease experts provide clinical guidance to help healthcare providers recognize, manage, and prevent measles in today’s outbreak-prone environment.

14 Apr 2025

ChatGPT improves exercise for neurodivergent kids

A University of Michigan research team has used AI to help deliver exercise "snacks" to kids with autism.

11 Apr 2025

New guidelines released for managing hypercholesterolemia in adults over 75

The National Lipid Association (NLA) and the American Geriatrics Society (AGS) have released a Joint Scientific Statement focused on the management of hypercholesterolemia in adults older than 75 years who do not have a history of atherosclerotic cardiovascular disease (ASCVD).

10 Apr 2025

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

10 Apr 2025

Treating SIBO holistically helps patients feel better, new study finds

A 90-day real-world study in Spain shows that a comprehensive, personalized treatment for SIBO significantly improves patients’ quality of life—even when breath tests remain abnormal.

7 Apr 2025

Heart failure linked to faster cognitive decline

There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study suggests.

3 Apr 2025

Blood cancer patients should continue BTKi therapy during COVID-19 vaccination

Blood cancer patients who receive a type of anti-cancer therapy should continue to take the drug while having COVID-19 vaccinations, a new study suggests.

2 Apr 2025

Terahertz imaging reveals cochlear structures with high resolution

Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions, this technology opens new possibilities for diagnosing hearing loss and other conditions.

27 Mar 2025

Unveiling leptin signaling in the DMH for metabolic effects

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use.

27 Mar 2025

Concierge approach enables more people to receive kidney transplants and erases disparities

Patients hoping for a kidney transplant must first undergo a battery of medical tests to determine whether they are suitable candidates for the procedure and healthy enough to take post-transplant immunosuppressant drugs to prevent organ rejection.

22 Mar 2025

Alzheimer's-modifying drug lecanemab's effectiveness may vary between genders

Since becoming only the second Alzheimer's-modifying drug to gain American Federal Drug Administration approval in 2023, sales of lecanemab, known by its brand name Leqembi, have risen steadily, reaching $87-million USD in the last quarter of 2024.

18 Mar 2025

Digitizing workflows: The role of AI and automation and how they are transforming efficiency in healthcare

The case for digitizing healthcare has never been more urgent. Hospitals are under pressure to deliver high-quality patient care, with demand increasing from an ageing population with complex healthcare needs.

18 Mar 2025

Denoised ultra-low dose CT offers safe pneumonia diagnosis for immunocompromised patients

Denoised ultra-low dose CT can effectively diagnose pneumonia in immunocompromised patients using only 2% of the radiation dose of standard CT, according to a study published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America.

13 Mar 2025

Enhancing pediatric health evaluations through improved PROMs

Children's health assessments differ significantly from adults due to varying cognitive abilities, language skills, and developmental stages. Patient-reported outcome measures (PROMs), which are self-reported questionnaires, offer valuable insights into a child's health status, but their design and implementation in pediatrics are complex.

10 Mar 2025

Can you trust TikTok for nutrition advice? Study exposes #WhatIEatinaDay

TikTok prioritizes engagement over accuracy, exposing young users to misleading nutrition content. Researchers urge stricter content moderation to curb misinformation.

26 Feb 2025