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Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases.

12 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Study outlines strategies people with visual impairment use to navigate social challenges

A recent study highlights the range of uncomfortable situations people living with blindness or visual impairment encounter due to interpersonal communication challenges, and outlines strategies people with visual impairment use to navigate these situations.

9 Aug 2022

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Early-life acquisition of antibiotic resistance in neonates from developing countries

Every year, almost 7 million potentially serious bacterial infections are estimated to occur in newborns, resulting in more than 550,000 annual neonatal deaths.

4 Aug 2022

Common viruses may play a role in some cases of Alzheimer's disease

Researchers from Oxford's Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer's disease (AD).

3 Aug 2022

Qualitative study aims to explore patients' perceptions of a teledermatology service

JMIR Publications recently published "Patients' Experiences of Telemedicine for Their Skin Problems: Qualitative Study" in JMIR Dermatology which reported that this qualitative study aimed to explore patients' perceptions of a teledermatology service linking public primary care clinics to the national specialist dermatology clinic in Singapore.

2 Aug 2022

Researchers unravel how one gut bacterium influences immunity

From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease.

27 Jul 2022

Survey: Telemedicine widely viewed as an effective means for delivering care

After experiencing a rapid expansion early in the COVID-19 pandemic, a new survey indicates that telemedicine is now widely viewed as an effective means for delivering care.

25 Jul 2022

Elephant genes could offer new clues to preventing cancer development

Scientists modeling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions - with implications for cancer treatments in humans.

19 Jul 2022

Grant funds research that investigates relationships between certain fungi and specific cancers

Dr. Iliyan D. Iliev, an associate professor of immunology and microbiology in the Division of Gastroenterology and Hepatology and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, has been awarded a five-year, $1.25 million CRI Lloyd J. Old STAR (Scientists Taking Risks) Program grant from Cancer Research Institute (CRI).

19 Jul 2022

Infection in early life can increase a baby's sensitivity to pain

Researchers from Oxford's Department of Pediatrics have discovered that infection can increase a baby's sensitivity to pain, which may last longer than the infection.

12 Jul 2022

University of Oxford begins recruiting for Phase I trial of new TB vaccine

The University of Oxford has begun recruiting for a Phase I trial with a tuberculosis vaccine in human volunteers at Oxford to develop a new way to test the efficacy of future TB vaccines - with the first volunteers being challenged today (Wednesday).

12 Jul 2022

Seeking to kick-start Biden’s agenda, Schumer unveils a bill for Medicare drug price negotiations

Democratic senators on Wednesday took a formal step toward reviving President Joe Biden's economic agenda, starting with a measure to let Medicare negotiate prices with drugmakers and to curb rising drug costs more broadly.

7 Jul 2022

How to get rid of medical debt — or avoid it in the first place

Lori Mangum was 32 when apple-size tumors sprouted on her head. Now — six years and 10 surgeries later — the skin cancer is gone. But her pain lives on, in the form of medical debt.

1 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

Patients to benefit from a super-charged clinical research system

Patients across the UK will benefit from a super-charged clinical research system, backed by £175 million of dedicated investment, which will save lives across the country.

30 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

The original SARS-CoV-2 viral strain that emerged in early 2020 was able to latch on to sugars known as sialic acids, found on the surface of human cells, an ability that later strains did not retain.

24 Jun 2022