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Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Examining differences in neurological manifestations induced by SARS-CoV-2 variants in hamsters

Researchers evaluated the neurological complications due to SARS-CoV-2 D614G strain, and variants of concern, Delta and Omicron in a hamster model.

28 Mar 2022

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

A team of international scientists has developed an mRNA-based coronavirus disease 2019 (COVID-19) vaccine encoding the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant. The vaccine candidate has shown high efficacy in inducing neutralizing antibodies and protecting against delta infection in mice. The study is currently available on the bioRxiv* preprint server.

24 Mar 2022

IgG Fc glycosylation: A marker for severe COVID-19

Researchers suggest that low anti-spike IgG1 glycosylation, sialyation, and high bisection are markers of severe COVID-19.

24 Mar 2022

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

Researchers investigated how monoclonal antibodies, S309 and AZD7442, reduced lung infection in mice infected with the SARS-CoV-2 new variant of concern Omicron's BA.1, BA.1.1, and BA.2 sublineages.

23 Mar 2022

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Researchers analyze the available scientific evidence supporting vitamin D as a neuroprotective agent against the neurological sequelae of COVID-19.

14 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Using Hla-A*32 allele as a prognostic indicator of COVID-19 severity

In a new study, researchers evaluated the association between human leukocyte antigens alleles and the severity of COVID-19.

2 Mar 2022

Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

In a new study, researchers used deep transcriptome analysis to examine the coding and non-coding transcriptional landscape of lung cells infected with SARS-CoV-2.

1 Mar 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

A broad evaluation of autoimmune disease-associated autoantibodies that have been observed in COVID-19 patients was performed.

22 Feb 2022

Chemokines News and Research

Phenotypic changes in monocytes from COVID-19 patients

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Role of SARS-CoV-2 S1 subunit in severe COVID-19

The different actions of CBD in SARS-CoV-2 infection

Examining differences in neurological manifestations induced by SARS-CoV-2 variants in hamsters

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

IgG Fc glycosylation: A marker for severe COVID-19

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

CD4 T-cell immunity active six months into COVID-19 convalescence

Using Hla-A*32 allele as a prognostic indicator of COVID-19 severity

Dual therapeutic potential of zapnometinib against COVID-19

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Analyzing transcriptomic landscape of SARS-CoV-2-infected lung cells

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

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