Endothelial cell News and Research

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Research drug may one day be novel treatment for systemic inflammatory response syndrome

When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection.

11 Jun 2018

Researchers develop injectable bandage to stop fatal blood loss, activate wound healing

While several products are available to quickly seal surface wounds, rapidly stopping fatal internal bleeding has proven more difficult.

22 May 2018

Research leads to new potential treatment for Hereditary Hemorrhagic Telangiectasia

The work of researchers Francesc Viñals and Mariona Graupera at the Bellvitge Biomedical Research Institute - Catalan Institute of Oncology - University of Barcelona, together with Dr. Antoni Riera-Mestre, has led to a new potential treatment for Hereditary Hemorrhagic Telangiectasia or Rendu-Osler Syndrome, a rare disease that affects blood vessels and had no described treatment.

26 Apr 2018

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

A proof-of-concept study carried out at UCL Institute of Ophthalmology with funding from Fight for Sight has highlighted the potential of a targeted antisense oligonucleotide therapy to treat Fuchs endothelial corneal dystrophy patients with a mutation in the TCF4 gene.

12 Mar 2018

Elevated levels of chlorinated lipids linked to lung injury and death in sepsis patients

In a study published in the Journal of Clinical Investigation Insight, Saint Louis University scientists have found that elevated levels of chlorinated lipids are linked to sepsis, lung injury and death. The finding may offer a way to diagnosis and treat sepsis earlier, saving lives and avoiding serious side effects.

31 Jan 2018

Vitamin D3 could prevent and repair cardiovascular damage, finds study

A new study by researchers at Ohio University found that Vitamin D3 could prevent and restore damage caused by several cardiovascular diseases.

31 Jan 2018

Researchers uncover powerful new model for studying hallmark of vascular disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

9 Jan 2018

Oncologists discover cell type that gives rise to soft tissue cancer in children

St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children.

8 Jan 2018

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports.

21 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

Corneal donor tissue can be safely stored for longer period, study finds

Results from a large, national clinical trial show that corneal donor tissue can be safely stored for 11 days without negatively impacting the success of transplantation surgery to restore vision in people with diseases of the cornea.

10 Nov 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

Researchers reveal how certain nerves sustain prostate cancer growth

In a study in today's issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate.

20 Oct 2017

Scientists identify potential treatment target for diabetic retinopathy

In oxygen-compromising conditions like diabetes, the body grows new blood vessels to help, but the result is often leaky, dysfunctional vessels that make bad matters worse.

10 Oct 2017

Scientists reveal engineered fusion protein that could recover blood vessel health

Scientists from Boston Children's Hospital Vascular Biology Program have revealed an engineered fusion protein that could recover blood vessel health following the onset of hypertension, atherosclerosis, stroke, heart attack, and other cardiovascular diseases.

16 Aug 2017

Salivary peptide promotes wound healing, research reveals

A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere.

7 Aug 2017

Vascularized 3D bioprinted liver tissue offers more accurate system for drug toxicity testing

Artificially constructed human tissues and organs have been developed with a number of different purposes in mind, from advanced robotics and novel materials to drug screening.

3 Aug 2017

Researchers present novel gene-editing technique to prevent retinal angiogenesis

A research team from the Schepens Eye Research Institute of Massachusetts Eye and Ear has successfully prevented mice from developing angiogenesis of the retina--the sensory tissue at the back of the eye--using gene-editing techniques with CRISPR-Cas9.

25 Jul 2017

Lipoprotein abnormalities linked to vaso-occlusive events in patients with sickle cell disease

An article published in Experimental Biology and Medicine (Volume 242, Issue 12, June, 2017) links imbalances in lipoprotein metabolism with vaso-occlusive events in patients with sickle cell disease

23 Jun 2017