Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals.

25 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

Study explores the effects of different diets on plasma proteins

Researchers investigated the relationship between diet and the proteome.

22 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023

Exploring developmental pathways and disease interactions in nervous and stomatognathic systems

Scientists discuss the intricate relationship between the nervous and stomatognathic systems.

21 Aug 2023

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Researchers used human transcriptomic data to differentiate the molecular mechanisms associated with two phenotypes of allergic rhinitis: rhinitis and rhinitis with asthma.

17 Aug 2023

Scientists develop new technique to "tattoo" living cells with nanomaterials

For now, cyborgs exist only in fiction, but the concept is becoming more plausible as science progresses.

10 Aug 2023

Lizards' ability to regenerate cartilage could lead to new treatments for osteoarthritis

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

10 Aug 2023

The immune-modulatory effect of lenvatinib investigated in new study

Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.

9 Aug 2023

Nanoscale tattoos for tracking the health of individual cells

Engineers have developed nanoscale tattoos - dots and wires that adhere to live cells - in a breakthrough that puts researchers one step closer to tracking the health of individual cells.

8 Aug 2023

Multifunctional Ga-based nanoparticles combine cancer phototherapy with immunotherapy

Researchers develop a novel cancer theranostic agent that can covert light energy to heat and in turn destroy cancer cells

4 Aug 2023

Researchers discover cause of cholesteatomas

Chronic inflammation of the middle ear can cause several problems and complications that can affect a person's hearing and balance.

3 Aug 2023

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma.

17 Jul 2023

Researchers identify a potential new drug for NASH-related fibrosis

Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with nonalcoholic steatohepatitis (NASH)-related fibrosis.

26 Jun 2023

COVID-19 susceptibility mechanism discovered using a newly created tool

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify genes and molecular pathways associated with disease risk that have previously been too complex to detect or interpret.

15 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023