Pituitary Gland News and Research

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Discovery of mutation in AIP gene associated with acromegaly

An indigenous family living in a mountainous area of Malaysian Borneo helped Van Andel Research Institute (VARI) researchers to discover information about genetic mutations associated with acromegaly, a form of gigantism that often results in enlarged hands, feet, and facial features.

24 Aug 2009

Giant pituitary adenoma can be safely removed through nasal route

It’s even worse than being told you have a brain tumor: having a tumor so large, it’s in a category all its own. Giant pituitary adenoma is a so-called “benign” tumor that can cause visual loss and impair many of the body’s most basic functions. But fortunately, even the largest of these giant tumors—which can grow to the size of an egg and invade nearby structures--can be treated effectively using a multimodality approach starting with minimally invasive surgery through the nose, according to a new study at the John Wayne Cancer Institute at Saint John’s Health Center.

12 Aug 2009

Review of endocrine disorders in the U.S.

A dogged review of the medical literature has produced what is believed to be the nation's first comprehensive estimate of the extent of dozens of endocrine disorders in the United States.

29 Jun 2009

Discovery of two proteins essential for ovulation

Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.

14 May 2009

Ferring Pharmaceuticals launches new trial of Degarelix for intermittent androgen deprivation therapy

Ferring Pharmaceuticals has announced the launch of a Phase IIIB clinical trial of degarelix for injection, a new injectable gonadotropin-releasing hormone (GnRH) receptor antagonist approved by the U.S. Food and Drug Administration (FDA) for the treatment of hormone sensitive advanced prostate cancer.

27 Apr 2009

First time portable CT used for skull base endoscopic transnasal surgery

When Susan Dailey was 11 years old, she was admitted to a hospital by her loving parents, who assumed she would get a routine tonsillectomy to cure her chronic sore throat.

20 Mar 2009

Protein that regulates hormones critical to women's health found in pituitary

University of Wisconsin-Madison researchers have solved the mystery surrounding a "rogue protein" that plays a role in the release of neurotransmitters and hormones in the brain.

12 Jan 2009

Schering-Plough announces European submission of fertility medicine Corifollitropin Alfa

Schering-Plough Corp. has announced that the European Medicines Agency (EMEA) has validated (accepted for review) its Marketing Authorization Application (MAA) for corifollitropin alfa, the company's experimental, sustained follicle stimulant (SFS).

1 Jan 2009

Degarelix prostate cancer drug makes testosterone levels fall dramatically and quickly

More than 95 per cent of men who took degarelix for prostate cancer saw their testosterone levels fall dramatically as early as three days after they started treatment, according to a paper in the December issue of BJU International.

3 Dec 2008

Study looks at investigational compound MK-677 in Alzheimer's disease

A new study shows that a drug that increases the release of growth hormone failed to slow the rate of progression of Alzheimer's disease in humans.

17 Nov 2008

Discovery of new gene responsible for puberty disorders

A new gene responsible for some puberty disorders has been identified by Medical College of Georgia researchers.

27 Oct 2008

Young type-2 diabetic men suffer low testosterone levels

Young men with type 2 diabetes have significantly low levels of testosterone, endocrinologists at the University at Buffalo have found -- a condition that could have a critical effect on their quality of life and on their ability to father children.

27 Aug 2008

Thyrotropin levels may be associated with coronary heart disease mortality in women

Women with increasing levels of thyrotropin within the normal range appear to have a higher risk of fatal coronary heart disease, according to a report in the April 28 issue of Archives of Internal Medicine.

28 Apr 2008

Scientists find distinct kind of stem cells in the pituitary gland

A team of researchers led by scientists at Cold Spring Harbor Laboratory have for the first time identified stem cells that allow the pituitary glands of mice to grow even after birth.

28 Apr 2008

Stress hormone impacts memory, learning in diabetic rodents

Diabetes is known to impair the cognitive health of people, but now scientists have identified one potential mechanism underlying these learning and memory problems.

18 Feb 2008

Human growth hormone abuse raises serious health risks

Human growth hormone (HGH), when medically necessary, is a safe and effective clinical treatment for children and adults.

13 Feb 2008

RNA interference therapy heals growth deficiency disorder in a live animal

A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal.

20 Dec 2007

New molecular evidence of the role of the hormone prolactin in breast cancer

They have found that prolactin, a pituitary hormone that normally stimulates breast development and milk production, initiates a new “signaling pathway” that may regulate the growth and survival of breast cancer cells.

29 Sep 2007

Exercise might actually increase the risk of developing ovarian cancer

Barcelona, Spain: A new study adds fuel to the debate over whether being fat or inactive affects the risk of developing ovarian cancer.

27 Sep 2007

Low birth weight children may be at a greater risk of stress-related health problems as adults

Findings from this study show that low birth weight (below the 10th percentile) can lead later in life to low concentrations of cortisol, a hormone that regulates stress response by adjusting blood pressure and blood sugar levels.

27 Sep 2007